Hypertension Clinical Trials

Showing 21-40 of 3,518 trials

A Phase 3 Study of Extended-release Tacrolimus in Subjects With Pulmonary Arterial Hypertension and Functional Limitations

NCT07612657

This study evaluates the effects of VI-0106 (an extended-release formulation of tacrolimus) in participants with pulmonary arterial hypertension (PAH) who continue to have functional limitations despite being on optimized background PAH therapy. Participants will be randomly assigned with equal chance to receive either VI-0106 or placebo in a double-blind fashion to assess whether VI-0106 improves outcomes in this population.

Pulmonary Arterial HypertensionPulmonary Arterial Hypertension (PAH)Pulmonary Arterial Hypertension (PAH) (WHO Group 1 PH)+2 more

VIVUS LLC300 participantsStarted May 2026

RECRUITING

Regional Innovation in Chronic Disease and Elderly Care

NCT07578090

This project aims to develop a community-based health promotion intervention model for populations at potential risk of metabolic syndrome. Through exercise training and lifestyle modifications, the project seeks to improve cardiopulmonary function and disease control, align with current public health policies, and establish an evidence-based model with strong potential for broader implementation.

HypertensionCardiovascular DiseaseHyperlipidemia+1 more

Fu Jen Catholic University1,000 participantsStarted May 2026

New Taipei City, Taiwan

COMPLETEDPhase 1

Clinical Trial to Evaluate the Pharmacokinetics and Safety Between the Single Administration of HL1113 and the Concomitant Administration of HL1113R1 and HL1113R2 for Healthy Subjects in Fasting State

NCT07568652

This clinical trial is a randomized, open-label, single oral dose, two-sequence, and two-period crossover study to evaluate the pharmacokinetics and safety between the single administration of HL1113 and the concomitant administration of HL1113R1 and HL1113R2 for healthy subjects in fasting state

HypertensionDiabete Type 2

Hanlim Pharm. Co., Ltd.37 participantsStarted Oct 2024

Seoul, South Korea

A Phase 3 Study of Extended-release Tacrolimus in Subjects With Pulmonary Arterial Hypertension and Functional Limitations

Regional Innovation in Chronic Disease and Elderly Care

Clinical Trial to Evaluate the Pharmacokinetics and Safety Between the Single Administration of HL1113 and the Concomitant Administration of HL1113R1 and HL1113R2 for Healthy Subjects in Fasting State

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A Study to Compare the Pharmacokinetics and Safety of the ATB-U101 and ATB-U1011+ATB-U1012 and ATB-1011+ATB-1012 in Healthy Caucasian Participants

Microplastics, Cirrhosis and Portal Hypertension

Self-Management and Resilience Trajectories in African American Adults With Hypertension

Treatment Outcomes for Portal Hypertension Esophageal and Gastric Varices

A Clinical Study of Sotatercept (MK-7962) in People With Pulmonary Arterial Hypertension (MK-7962-038)

Natural History of Noncirrhotic Portal Hypertension

Evaluation of Physical Fitness and Hemodynamics Across a Diverse Population

Riociguat in Children With Pulmonary Arterial Hypertension (PAH)

An Adaptive Program of IKT-001 in Pulmonary Arterial Hypertension (PAH)

Effects of Laser Acupuncture Treatment in Hypertension Haemodialysis Patients

A Study of Selexipag as Add-On Treatment to Standard of Care in Children With Pulmonary Arterial Hypertension

Is the Two-minute Step Test an Alternative to the Six-minute Walk Test in Pulmonary Hypertension?

The Use of Virtual Reality and Music Therapy for Hypertensive Urgency

A Study of Macitentan in Japanese Pediatric Participants With Pulmonary Arterial Hypertension

Spyral InSight Study

The PreEclampsia Postpartum Prevention Trial

Supporting VETerans With Kidney Disease Through Food As Medicine