Liver cirrhosis:diagnosed based on histology or unequivocal clinical, sonographic, and laboratory findings
19≤age≤75
Hepatic venous pressure gradient \> 12 mmHg
Informed consent
You may not be if
Shock status requiring vasopressor
Active infection, for example Spontaneous bacterial peritonitis
Acute renal failure patients of any cause
Clinically relevant coronary artery disease(NYHA functional angina classification III/IV),congestive heart failure NYHA III/IV), clinically relevant cardiomyopathy, history of myocardial infarction in the past 12 months
Poorly controlled hypertension (BP 150/100mmHg)
Hepatocellular carcinoma
History of another primary malignancy ≤ 3years
Medical or psychological conditions that would not permit the subject to complete thte study or sign informed consent
Pregnancy or lactation period
Serum creatinine ≧ 6mg/dL
Involvement in the conduct of other study within 30 days
Known hypersensitivity to Rifaximin or propranolol
Dysarrhythmia, inappropriate for study on investigator's judgment
