Clinical Trials in Seattle

Showing 5261-5280 of 9,312 trials

A Dose-escalation Pharmacokinetic Study of Intravenous ASA404 in Adult Advanced Cancer Patients With Impaired Renal Function and Patients With Normal Renal Function

NCT01278758

The purpose of this study is to evaluate the safety and pharmacokinetics of ASA404 in patients with refractory or relapsed metastatic cancer with impaired renal function and with normal renal function. It is very possible that patients with renal impairment will show differences in renal excretion of parent ASA404 and its metabolites, warranting a study that leads to a better pharmacokinetic assesssment in this population.

Metastatic Cancer

Novartis Pharmaceuticals7 participantsStarted Mar 2010

Indianapolis, Indiana, United States • Rockville, Maryland, United States • Detroit, Michigan, United States +1 more locations

COMPLETEDNA< 1 mile

Pilot Trial of the First Conversational Agent for Smoking Cessation (QuitBot)

NCT03585231

Conversational agents (CAs) are computer-powered digital coaches designed to form long-term social-emotional connections with users through conversations. We have developed a CA for cigarette smoking cessation. In a pilot randomized trial (N = 415), we will compare the experimental messaging program (n = 155) with the standard of care national government smoking cessation messaging program (n = 157), and then we will compare immediate (n=51) versus delayed (n=51) access to the the experimental messaging program, to assess 12-week usability, receptivity, and preliminary cessation results in adults in western Washington State and nationally across the US who want to quit smoking.

Smoking Cessation

Fred Hutchinson Cancer Center404 participantsStarted Sep 2018

Seattle, Washington, United States

A Dose-escalation Pharmacokinetic Study of Intravenous ASA404 in Adult Advanced Cancer Patients With Impaired Renal Function and Patients With Normal Renal Function

Pilot Trial of the First Conversational Agent for Smoking Cessation (QuitBot)

Find Trials by Condition in Seattle

Study of Epratuzumab Versus Placebo in Subjects With Moderate to Severe General Systemic Lupus Erythematosus (SLE)

MMF for HIV Reservoir Reduction

Follow-up of the PEPITES Study to Evaluate Long-term Efficacy and Safety of Viaskin Peanut in Children

Combination Immunotherapy With Herceptin and the HER2 Vaccine NeuVax

The Assessment of Copper Parameters in Wilson Disease Participants on Standard of Care Treatment

Clinical Evaluation of PROMIS in CKD

Effects of Oxytocin on Bleeding Outcomes During Dilation and Evacuation

Interdisciplinary Case-Control Study of Non-Hodgkin's Lymphoma

Levofloxacin in Preventing Infection in Young Patients With Acute Leukemia Receiving Chemotherapy or Undergoing Stem Cell Transplantation

Canadian Humira Post Marketing Observational Epidemiological Study: Assessing Effectiveness in Ankylosing Spondylitis

Fixation Using Alternative Implants for the Treatment of Hip Fractures (FAITH-2)

Endoscopic Ultrasound (EUS)-Guided Fine Needle Aspiration (FNA) With Rapid On-site Evaluation (ROSE) of Cytopathology vs. EUS-guided Fine Needle Biopsy (FNB) Alone in the Diagnosis of Pancreatic Solid Lesions

Conventional Versus RF Needle Transseptal Puncture for Cryoballoon Ablation

A Phase 2 Study to Evaluate the Safety, Efficacy, Pharmacokinetics and Pharmacodynamics of PF-06252616 in Duchenne Muscular Dystrophy

MRI Biomarkers in ALS

Fluid Responsiveness Evaluation in Sepsis-associated Hypotension

Safety and Efficacy of Turoctocog Alfa in Prevention and Treatment of Bleeds in Previously Untreated Children With Haemophilia A

Safety and Efficacy of Exenatide as Monotherapy and Adjunctive Therapy to Oral Antidiabetic Agents in Adolescents With Type 2 Diabetes