Clinical Trials in Seattle

Showing 4161-4180 of 9,312 trials

A Study of Daratumumab in Patients With Relapsed or Refractory Waldenström Macroglobulinemia

NCT03187262

This research study is studying Daratumumab as a possible treatment for Waldenström Macroglobulinemia.

Dana-Farber Cancer Institute13 participantsStarted Nov 2017

Boston, Massachusetts, United States • Boston, Massachusetts, United States • Rochester, Minnesota, United States +2 more locations

COMPLETEDPhase 4< 1 mile

Management of Pleural Space Infections

NCT03873766

Currently, there is no high-quality evidence comparing the clinical outcomes and cost effectiveness of surgical drainage combined with antibiotics versus dual-agent intrapleural fibrinolytic therapy (IPFT) catheter drainage of pleural space infections with concomitant antibiotic therapy. The absence of comparative data is a challenge for surgical and medical services in clinical decision-making for this common and morbid condition. This is a pilot study comparing surgical drainage of the pleural space in complex pleural effusions to bedside chest tube drainage using dual agent IPFT with the intent to inform on study algorithm and endpoint performance in anticipation of a multi-institutional randomized clinical trial.

Empyema, PleuralParapneumonic Effusion

Swedish Medical Center26 participantsStarted Apr 2019

Seattle, Washington, United States

A Study of Daratumumab in Patients With Relapsed or Refractory Waldenström Macroglobulinemia

Management of Pleural Space Infections

Find Trials by Condition in Seattle

THE ALIGN-AR EFS TRIAL: JenaValve Pericardial TAVR Aortic Regurgitation Study

Self-Management Interventions for Chronic Pain Relief With Cancer Survivors

A Phase III Trial of Niraparib Versus Physician's Choice in HER2 Negative, Germline BRCA Mutation-positive Breast Cancer Patients

Therapeutic Autologous Lymphocytes, Aldesleukin, and Denileukin Diftitox in Treating Patients With Stage III-IV Melanoma

A Study of Polatuzumab Vedotin (DCDS4501A) in Combination With Rituximab or Obinutuzumab Plus Bendamustine in Participants With Relapsed or Refractory Follicular or Diffuse Large B-Cell Lymphoma

Pembrolizumab With Talimogene Laherparepvec or Placebo in Unresected Melanoma

TruGraf® Long-term Clinical Outcomes Study

Tumor-Infiltrating Lymphocytes After Combination Chemotherapy in Treating Patients With Metastatic Melanoma

Sotrovimab Expanded Access Treatment Protocol (COVID-19)

A Study of Escitalopram in the Treatment of Children and Adolescents With Generalized Anxiety Disorder

Long-Term Study of Hydrocodone Bitartrate Controlled-release Capsules in Subjects With Chronic Pain

LAPLACE-TIMI 57: Low-density Lipoprotein Cholesterol (LDL-C) Assessment With PCSK9 monoclonaL Antibody Inhibition Combined With Statin thErapy

Predictive Assay for Decision Making in Adjuvant Therapy

Topical Ruxolitinib Evaluation in Chronic Hand Eczema Study 2

Proof-of-Concept Study to Assess the Efficacy, Safety and Tolerability of SAR440340 (Anti-IL-33 mAb) in Patients With Moderate-to-severe Chronic Obstructive Pulmonary Disease (COPD)

Effect of Adaptive Servo Ventilation (ASV) on Survival and Hospital Admissions in Heart Failure

Safety, Tolerability, and Efficacy of IONIS-GHR-LRx in Participants With Acromegaly Being Treated With Long-acting Somatostatin Receptor Ligands

A Platform Study of Novel Immunotherapy Products in Participants With Previously Treated Unresectable or Metastatic Cutaneous Melanoma