Clinical Trials in Miami

Showing 5701-5720 of 11,431 trials

Ph1 Administration of VSV-IFNβ-NIS Monotherapy and in Combination With Avelumab in Pts With Refractory Solid Tumors

NCT02923466

This is a three-part open label phase 1 study designed to determine the safety profile, MTD, PK and tumor and biomarker response after IT or IV administration of a single dose of VSV-IFNβ-NIS, or combined IT followed by IV VSV-IFNβ-NIS, with or without IV avelumab every two weeks, in patients with refractory advanced/metastatic solid tumors.

Malignant Solid Tumour

Vyriad, Inc.76 participantsStarted Apr 2017

Miami, Florida, United States • Minneapolis, Minnesota, United States • Columbus, Ohio, United States +3 more locations

WITHDRAWNPhase 3< 1 mile

To Assess Effects of Arbaclofen ER Tablets Compared With Placebo on Sperm Parameters in Male Subjects With MS

NCT02869425

This study is designed to assess the effects of a therapeutic dose of arbaclofen extended release (ER) tablets compared with placebo on human sperm concentration, motility, and morphology in male subjects with multiple sclerosis (MS).

Multiple SclerosisSperm

RVL Pharmaceuticals, Inc.Started Jul 2016

Miami, Florida, United States • Tampa, Florida, United States

COMPLETEDPhase 2< 1 mile

Linaclotide Safety and Efficacy in 2 to 5-Year-Old Participants With Functional Constipation

NCT04110145

The purpose of this study is to evaluate the dose response, safety, and efficacy of linaclotide when compared with placebo in pediatric participants, 2 to 5 years of age, with Functional Constipation.

Functional Constipation

Allergan35 participantsStarted Oct 2019

Birmingham, Alabama, United States • Hot Springs, Arkansas, United States • Little Rock, Arkansas, United States +15 more locations

Ph1 Administration of VSV-IFNβ-NIS Monotherapy and in Combination With Avelumab in Pts With Refractory Solid Tumors

To Assess Effects of Arbaclofen ER Tablets Compared With Placebo on Sperm Parameters in Male Subjects With MS

Linaclotide Safety and Efficacy in 2 to 5-Year-Old Participants With Functional Constipation

Find Trials by Condition in Miami

A Study to Evaluate the Safety and Efficacy of CR845 in Hemodialysis Patients With Moderate-to-Severe Pruritus (KALM-1)

Convalescent Plasma to Stem Coronavirus (CSSC-001)

Efficacy and Safety of AMR101 (Ethyl Icosapentate) in Patients With Fasting Triglyceride (Tg) Levels ≥ 500 and ≤ 2000 mg/dL

Sotagliflozin Bioequivalence Study

A Bioequivalence Study Testing Two Formulations of Sotagliflozin in Healthy Male and Female Subjects Under Fasted Conditions

Effect of AMR101 (Ethyl Icosapentate) on Triglyceride (Tg) Levels in Patients on Statins With High Tg Levels (≥ 200 and < 500 mg/dL)

Effect of Venglustat in Patients With Renal Impairment

Well-Being and Physical Activity Study

The ADAPT Study: Assessment of the DiAgnostic Performance of DeepVessel FFR in SuspecTed Coronary Artery Disease

An Extension Study in Participants With Moderate to Severe Rheumatoid Arthritis

Efficacy Study of Arbaclofen to Treat Spasticity in Multiple Sclerosis

One Year, Open Label, Dose Escalation Long-term Safety Study in Multiple Sclerosis (MS) Subjects With Spasticity

Ph 1-2 Study ADI-PEG 20 Plus FOLFOX in Subjects With Advanced GI Malignancies Focusing on Hepatocellular Carcinoma

Integrase and Maraviroc Intensification in Neurocognitive Dysfunction (InMIND)

Safety and Tolerability of WVE-120102 in Patients With Huntington's Disease

Twelve -Month Study Observing How Insulin-naïve Patients With Type 2 Diabetes Mellitus Manage Diabetes Using Toujeo® After Oral Antidiabetic Drug Failure, the Side Effect of Toujeo®, and The Cost.

A Study of the Efficacy and Safety of Hematopoietic Stem Cells Transduced With Lenti-D Lentiviral Vector for the Treatment of Cerebral Adrenoleukodystrophy (CALD)