Clinical Trials in Boston

Showing 6701-6720 of 17,836 trials

Relationship Between Strain and Stroke Volume in Cardiac Surgery

NCT04694378

Patients undergoing coronary artery bypass grafting up tp 30% will develop postoperative right ventricle dysfunction. Its imperative for the physician to fully understand the severity of this complication in order to perform an early diagnosis and carry out the appropriate treatment. Aim: Investigate the correlation between echocardiographic measurements and hemodynamic changes at different time points in patients undergoing coronary artery bypass graft surgery Hypothesis: 1. Weak correlation between echocardiographic measurements and hemodynamic changes during coronary artery bypass graft surgery 2. Echocardiographic measurements would change across different time points during surgery independent of hemodynamic values.

Right Ventricular DysfunctionStroke Volume IndexLongitudinal Heart Strain

Tufts Medical Center30 participantsStarted Oct 2020

Boston, Massachusetts, United States

TERMINATEDPhase 1/2< 1 mile

A Study of Intraperitoneally Administered AVB-001 in Patients With Serous Adenocarcinoma of the Ovary

NCT05538624

This is an open-label, First-in-Human, Phase 1/2, multicenter study to evaluate the safety and efficacy of a single dose of AVB-001. AVB-001 is an encapsulated cell product engineered to produce native human interleukin-2 (hIL-2). It is delivered intraperitoneally (IP) to patients with high grade serous adenocarcinoma of the ovary, primary peritoneum, or fallopian tube.

Neoplasm, OvarianFallopian Tube CancerPrimary Peritoneal Cavity Cancer+5 more

Avenge Bio, Inc14 participantsStarted Dec 2022

Bethesda, Maryland, United States • Boston, Massachusetts, United States • Pittsburgh, Pennsylvania, United States +2 more locations

Relationship Between Strain and Stroke Volume in Cardiac Surgery

A Study of Intraperitoneally Administered AVB-001 in Patients With Serous Adenocarcinoma of the Ovary

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Effect of Acupuncture and Pain Medication on Radicular Pain Using QST

Expanded Access Protocol: Repeated Administration of Nurown® (Autologous MSC-NTF Cells) for the Treatment of ALS

PH 1 Biomarker Study of Nivolumab and Ipilimumab and Nivolumab in Combination With Ipilimumab in Advanced Melanoma

Safety and Tolerability of Patisiran (ALN-TTR02) in Transthyretin (TTR) Amyloidosis

Real-world Effectiveness and Cardiovascular Safety Study of Abaloparatide in Postmenopausal Women

Hydroxocobalamin Approach for Reducing of Calprotectin With Butyrate for Ulcerative Colitis Remission

The TESLA Trial: Thrombectomy for Emergent Salvage of Large Anterior Circulation Ischemic Stroke

Pilot Testing an Innovative Physical Activity Intervention for Parents Attending Their Children's Sport Practices

Recent-Onset Type 1 Diabetes Trial Evaluating Efficacy and Safety of Teplizumab

Mogamulizumab Q4week Dosing in Participants With R/R CTCL

A Study to Investigate the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics and Efficacy of Risdiplam (RO7034067) in Type 2 and 3 Spinal Muscular Atrophy (SMA) Participants

Understanding Decision Making in the Intensive Care Unit: a National Study

Efficacy and Safety of Circadin® in the Treatment of Sleep Disturbances in Children With Neurodevelopment Disabilities

Craniofacial Microsomia: Accelerating Understanding of the Significance and Etiology

Cerclage On LOw Risk Singletons: Cervical Cerclage for Prevention of Spontaneous Preterm Birth in Low Risk Singleton Pregnancies With Short Cervix

Efficacy and Safety of S95011 in Primary Sjögren's Syndrome Patients

The Effect of Intrawound Vancomycin Powder in Spine Surgery

A Trial to Evaluate the Effect of Food on LEO 152020