Clinical Trials in Boston

Showing 6721-6740 of 17,836 trials

Safety and Tolerability of Patisiran (ALN-TTR02) in Transthyretin (TTR) Amyloidosis

NCT01617967

This was a multiple dose, dose escalation study designed to determine the safety, tolerability, pharmacokinetics and pharmacodynamics of patisiran (ALN-TTR02) in participants with transthyretin (TTR) mediated amyloidosis (ATTR).

TTR-mediated Amyloidosis

Alnylam Pharmaceuticals29 participantsStarted May 2012

Boston, Massachusetts, United States • Rio de Janeiro, Brazil • Le Kremlin-Bicêtre, France +7 more locations

UNKNOWNNA< 1 mile

DuraSorb® in Prosthetic Breast Reconstruction

NCT04646057

This study compares outcomes of prospective mesh-based breast reconstructions to historical control breast reconstructions with no mesh.

Breast Reconstruction

Surgical Innovation Associates, Inc.168 participantsStarted Jan 2021

Chicago, Illinois, United States • Chicago, Illinois, United States • Evanston, Illinois, United States +4 more locations

TERMINATEDPhase 3< 1 mile

A Study to Evaluate the Efficacy and Safety of Recombinant Human Pentraxin-2 (rhPTX-2; PRM-151) in Participants With Idiopathic Pulmonary Fibrosis

NCT04552899

This phase III study will evaluate the efficacy, safety and pharmacokinetics (PK) of recombinant human pentraxin-2 (rhPTX-2; PRM-151) zinpentraxin alfa, compared with placebo in participants with idiopathic pulmonary fibrosis (IPF).

Idiopathic Pulmonary Fibrosis

Hoffmann-La Roche665 participantsStarted Mar 2021

Birmingham, Alabama, United States • Phoenix, Arizona, United States • Phoenix, Arizona, United States +357 more locations

Safety and Tolerability of Patisiran (ALN-TTR02) in Transthyretin (TTR) Amyloidosis

DuraSorb® in Prosthetic Breast Reconstruction

A Study to Evaluate the Efficacy and Safety of Recombinant Human Pentraxin-2 (rhPTX-2; PRM-151) in Participants With Idiopathic Pulmonary Fibrosis

Find Trials by Condition in Boston

Evaluation of Dalteparin for Long-term (One Year) Treatment of Blood Clots in Subjects With Cancer

A Study to Evaluate PF-06730512 in Adults With Focal Segmental Glomerulosclerosis (FSGS)

SL-401 in Combination With Pomalidomide and Dexamethasone in Relapsed or Relapsed and Refractory Multiple Myeloma

Preliminary Study 2 to Test the Effects of Ambulatory Voice Biofeedback

A Study to Assess the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of AG-946 in Healthy Volunteers and in Participants With Sickle Cell Disease

Impact of Decision Aids in Urogynecology

Study To Evaluate The Efficacy And Safety Of Balovaptan In Adults With Post-Traumatic Stress Disorder (PTSD)

A Study to Evaluate the Effect of Dupilumab on Exercise Capacity in Adult Patients With Asthma

A Study to Test if TVB-009P is Effective in Relieving Postmenopausal Osteoporosis

A Study to Evaluate the Efficacy and Safety of Bintrafusp Alfa (M7824) Monotherapy in Metastatic or Locally Advanced Urothelial Cancer

Study of Efficacy and Safety of CTL019 in Adult DLBCL Patients

A Study to Evaluate the Efficacy, Safety, and Pharmacokinetics of BFKB8488A Compared With Placebo in Participants With Non-Alcoholic Steatohepatitis

Prospective Multicenter Evaluation of a New Predictive Model for the Progression of Adolescent Idiopathic Scoliosis

Combination Chemotherapy and Cyclosporine Followed by Focal Therapy for Bilateral Retinoblastoma

Evaluation of Efficacy and Safety of Iloperidone in the Acute Treatment of Manic or Mixed Episodes Associated With Bipolar I Disorder

OPTIMISE-CKD Drug Utilization

Epigenetics, Vitamin C, and Abnormal Blood Cell Formation - Vitamin C in Patients With Low-Risk Myeloid Malignancies