Clinical Trials in Boston

Showing 2941-2960 of 15,299 trials

The Physiology of Human Brown Adipose Tissue

NCT04352244

Brown fat is a type of fat, found in both children and adults, which can produce heat and regulate the body's metabolism and energy use. White fat is the more common type of fat which is used to store extra calories. Understanding more about differences between brown and white fat may allow us to develop new approaches to improve the body's metabolism.

Adipose Tissue, BrownAdipose TissueObesity

Beth Israel Deaconess Medical Center40 participantsStarted Mar 2020

Boston, Massachusetts, United States

COMPLETEDPhase 3< 1 mile

Pivotal, Open-label, Randomized Study of Radiosurgery With or Without Tumor Treating Fields (TTFields) for 1-10 Brain Metastases From Non-small Cell Lung Cancer (NSCLC).

NCT02831959

The study is a prospective, randomized controlled phase III trial, to test the efficacy, safety and neurocognitive outcomes of advanced NSCLC patients, following stereotactic radiosurgery (SRS) for 1 inoperable brain metastasis or 2-10 brain metastases, treated with NovoTTF-200M and supportive treatment compared to supportive treatment alone. The device is an experimental, portable, battery operated device for chronic administration of alternating electric fields (termed TTFields or TTF) to the region of the malignant tumor, by means of surface, insulated electrode arrays.

Brain Metastases From Non-small Cell Lung Cancer (NSCLC)

NovoCure GmbH298 participantsStarted Jul 2016

Birmingham, Alabama, United States • Birmingham, Alabama, United States • Mobile, Alabama, United States +125 more locations

The Physiology of Human Brown Adipose Tissue

Pivotal, Open-label, Randomized Study of Radiosurgery With or Without Tumor Treating Fields (TTFields) for 1-10 Brain Metastases From Non-small Cell Lung Cancer (NSCLC).

Find Trials by Condition in Boston

BTX-A51 in Patients With Liposarcoma or CIC-rearranged Sarcoma

Duvelisib Plus Docetaxel In Recurrent/Metastatic HNSCC

Comparative Effectiveness of Tirzepatide Versus Sitagliptin in Individuals at Cardiovascular Risk (TIRZSITA-CVOT)

To Evaluate Safety and Tolerability of the Fixed- Dose Combination of Obeticholic Acid and Bezafibrate

Efficacy and Safety of Encaleret Compared to Standard of Care in Participants With ADH1

SARC044: A Phase II Trial of Bezuclastinib in Combination With Sunitinib in Patients With GIST

PROSTATE-IQ: Parallel RandOmized STudy of Personalized Apalutamide Treatment and Evaluation to Improve Quality of Life in Post-Operative Radiation With Androgen Axis Suppression. A Phase III Multi-center Study for Men With Detectable PSA After Prostatectomy for Prostate Cancer.

OCS Heart Perfusion Post-Approval Registry

The CALERIE™ Legacy Study

Skeletal Health and Bone Marrow Composition in Adolescents With Cystic Fibrosis

A Phase 2a Proof-of-Concept Trial of Bempikibart (ADX-914) for the Treatment of Severe Alopecia Areata (SIGNAL-AA)

Designing a Mobile App to Support Academic Success for Student Veterans

Paclitaxel, Carboplatin, and Bevacizumab or Paclitaxel, Carboplatin, and Temsirolimus or Ixabepilone, Carboplatin, and Bevacizumab in Treating Patients With Stage III, Stage IV, or Recurrent Endometrial Cancer

Gastrointestinal Response of Pediatric Cystic Fibrosis Patients on Mediterranean Diet

Post-Market Study to Assess iTind Safety in Comparison to UroLift

A Study to Evaluate the Efficacy and Safety of Pegcetacoplan in Patients With Cold Agglutinin Disease (CAD)

Multicenter Assessment of the Pancreas in Type 1 Diabetes

Phase 3, Randomized, Placebo-Controlled Study of Tinlarebant to Explore Safety and Efficacy in Adolescent Stargardt Disease