Clinical Trials in Boston

Showing 2961-2980 of 15,299 trials

Study of Disease Progression in Adults With Inherited Forms of Spastic Paraplegia

NCT05008874

The course of AMN-related disabilities over time is poorly or incompletely understood due to a limited number of patients and lack of treatments. This study will help obtain a better understanding of the progression of disease with AMN and facilitate efficient clinical development of future interventional medications.

AMNAMN Gene MutationX-ALD

SwanBio Therapeutics, Inc.65 participantsStarted Jun 2021

Stanford, California, United States • Boston, Massachusetts, United States • New York, New York, United States +3 more locations

RECRUITINGNA< 1 mile

Gut Mini-Pill Study

NCT07220369

The purpose of this proof-of-concept study in humans is to determine if a noninvasive, ingestible device, called a "mini-pill", can collect gastrointestinal (GI) luminal content samples from 2 different locations along the GI tract after consumption of diets differing in protein source (meat and plant-based meat alternatives). The mini-pills will be recovered in the stool. We will analyze the microbial profile of the mini-pill contents and in stool, and also measure blood biomarkers related to cardiometabolic risk, to better understand the relationship between diet, microbiota and health.

Gut Microbiota

Tufts University30 participantsStarted Sep 2025

Boston, Massachusetts, United States

Active Not Recruiting< 1 mile

The CALERIE™ Legacy Study

NCT05651620

The purpose of the CALERIE Legacy Study is to follow up on the health and wellness of participants from phase 2 of the Comprehensive Assessment of Long-term Effects of Reducing Intake of Energy (CALERIE) trial, which was conducted from 2007 to 2011.

Calorie Restriction

Tufts University216 participantsStarted Apr 2023

Baton Rouge, Louisiana, United States • Boston, Massachusetts, United States • St Louis, Missouri, United States

Study of Disease Progression in Adults With Inherited Forms of Spastic Paraplegia

Gut Mini-Pill Study

The CALERIE™ Legacy Study

Find Trials by Condition in Boston

Telemedicine-Delivered Unified Protocol for Cognitive Behavioral Therapy for Anxiety and Depression

Extended Treatment Protocol for Subjects Continuing to Benefit From Ibrutinib.

Pragmatic Implementation Trial of a CF Primary Palliative Care Intervention

OCS Heart Perfusion Post-Approval Registry

Dose-Ranging Safety, Tolerability, and Efficacy Study of AZD2373 in Participants With APOL1-Mediated Kidney Disease

Stimulant Therapy Targeted to Individualized Connectivity Maps to Promote ReACTivation of Consciousness

Biology of Young Lung Cancer Study: The YOUNG LUNG Study

Non-Invasive Monitoring Methods in Patients With Acute Brain Injury

Study to Compare the Safety and Efficacy of IDP-126 Gel to Epiduo® Forte Gel and Vehicle Gel

KYSA-1: A Study of Anti-CD19 Chimeric Antigen Receptor T-Cell (CD19 CAR T) Therapy, in Subjects With Refractory Lupus Nephritis

Musical Playlist of the Grief Journey

Study to Assess Adverse Events and Change in Disease Activity in Adult Participants With Advanced Solid Tumors Receiving Intravenous (IV) ABBV-400 as Monotherapy and in Combination With IV Bevacizumab

A Study to Evaluate the Efficacy and Safety of Pegcetacoplan in Patients With Cold Agglutinin Disease (CAD)

Study of Ulevostinag (MK-1454) Alone or in Combination With Pembrolizumab (MK-3475) in Participants With Advanced/Metastatic Solid Tumors or Lymphomas (MK-1454-001)

A Study of Pembrolizumab (MK-3475) in Relapsed or Refractory Classical Hodgkin's Lymphoma (rrcHL) or Relapsed or Refractory Primary Mediastinal Large B-cell Lymphoma (rrPMBCL) (MK-3475-B68)

Study of Intratumoral (IT) Ulevostinag (MK-1454) in Combination With Intravenous (IV) Pembrolizumab (MK-3475) Compared to IV Pembrolizumab Alone as the First Line Treatment of Metastatic or Unresectable, Recurrent Head and Neck Squamous Cell Carcinoma (HNSCC) (MK-1454-002)

Evaluation of Liver Stiffness Performance, by FibroScan®, to Detect Elevated Central Venous Pressure (CVP)