Clinical Trials in Arizona

Showing 5041-5060 of 16,770 trials

TAEK-VAC-HerBy Vaccine for Brachyury and HER2 Expressing Cancer

NCT04246671

A Phase 1 open label trial of intravenous administration of TAEK-VAC-HerBy vaccine in patients with advanced brachyury and/or HER2- expressing cancer. The study will be completed in 2 stages. In Stage 1 patients will be enrolled and treated according to a 3+3 dose escalation scheme. Up to 4 dose levels will be explored to determine the recommended dose of TAEK-VAC-HerBy for Stage 2 of the trial. Stage 2 will enroll either chordoma patients for treatment with TAEK-VAC-HerBy alone, or HER2- positive breast cancer patients for combination treatment of TAEK-VAC-HerBy vaccine and therapeutic HER2 antibodies (trastuzumab). Patients in both stages will receive TAEK-VAC-HerBy intravenously, every three weeks, three administrations in total.

ChordomaHER2-positive Breast Cancer

Bavarian Nordic37 participantsStarted Aug 2020

Scottsdale, Arizona, United States • Santa Monica, California, United States • Jacksonville, Florida, United States +6 more locations

TERMINATEDPhase 231 miles

A Phase 2 Study of IW-3300 for the Treatment of Bladder Pain in Subjects With Interstitial Cystitis/Bladder Pain Syndrome

NCT05740007

The aim of this study is to assess whether IW-3300 is safe and works for the treatment of interstitial cystitis/bladder pain syndrome (IC/BPS). The main question the study aims to answer is whether IW-3300 helps bladder pain and other symptoms (for example, bladder burning, pressure and discomfort). Subjects will be assigned to receive either the study drug or placebo by chance.

Interstitial CystitisBladder Pain Syndrome

Ironwood Pharmaceuticals, Inc.98 participantsStarted Mar 2023

Mobile, Alabama, United States • Mobile, Alabama, United States • Scottsdale, Arizona, United States +50 more locations

TAEK-VAC-HerBy Vaccine for Brachyury and HER2 Expressing Cancer

A Phase 2 Study of IW-3300 for the Treatment of Bladder Pain in Subjects With Interstitial Cystitis/Bladder Pain Syndrome

Find Trials by Condition in Arizona

Azacitidine and Combination Chemotherapy in Treating Infants With Acute Lymphoblastic Leukemia and KMT2A Gene Rearrangement

A Phase 2b Study of Icosabutate in Fatty Liver Disease

Phase 2 Trial to Evaluate Belzupacap Sarotalocan (AU-011) Via Suprachoroidal Administration in Subjects With Primary Indeterminate Lesions and Small Choroidal Melanoma

Safety and Efficacy of Oral GKT137831 in Patient With Type 2 Diabetes and Albuminuria

EPI-7386 in Combination with Enzalutamide Compared with Enzalutamide Alone in Subjects with MCRPC

XB2001 in Combination With ONIVYDE + 5-FU/LV (+Folinic Acid) in Advanced Pancreatic Cancer

Hokusai Study in Pediatric Patients With Confirmed Venous Thromboembolism (VTE)

Safety and Effectiveness Study of Endovascular Abdominal Aortic Aneurysm Repair Using the Nellix® System

Oral EPI-7386 in Patients with Castration-Resistant Prostate Cancer

Combination of BTL-785F and HPM-6000UF Devices for Women's Intimate Wellness

A Study of AK104, a PD-1/CTLA-4 Bispecific Antibody in Subjects With Recurrent/Metastatic Cervical Cancer

A Phase II, Randomized, Double-blind, Placebo-controlled Study to Assess MEDI3506 in Participants With COPD and Chronic Bronchitis

First-in-human Study of DB-1305/BNT325 for Advanced/Metastatic Solid Tumors

TREAT-BE Study (Treatment With Resection and Endoscopic Ablation Techniques for Barrett's Esophagus)

A Safety Trial of Lisocabtagene Maraleucel (JCAR017) for Relapsed and Refractory (R/R) B-cell Non-Hodgkin Lymphoma (NHL) in the Outpatient Setting (TRANSCEND-OUTREACH-007)

Cardiovascular Risk Screening and Risk Reduction in Women Vets

Lipoic Acid for Progressive Multiple Sclerosis (MS)

An Observational Study to Assess Change in Disease Activity and Adverse Events of Upadacitinib in Adult Participants With Moderate to Severe Ulcerative Colitis (UC) in Real-World Practice