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Clareo Health | Lung Cancer Clinical Trials in Philadelphia | 480 Studies

Clinical Trials Lung CancerPhiladelphia

Lung Cancer Clinical Trials in Philadelphia

Find 480 clinical trials for lung cancer near Philadelphia, Pennsylvania. Connect with research centers in your area.

All Lung Cancer trials nationwide All trials in Philadelphia

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RecruitingNot yet recruitingActive, not recruitingEnrolling by invitationCompletedTerminated

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Early phase 1Phase 1Phase 1–2Phase 2Phase 2–3Phase 3Phase 4No phase

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Showing 461-480 of 480 trials

RecruitingA Phase 1 Study of LNCB74 in Advanced Solid TumorsThis is an open-label, phase 1, dose escalation and dose expansion study to determine safety and tolerability, and to determine the maximum tolerated dose and / or recommended…NCT06774963·Newport Beach, California and 13 others CompletedSafety and Efficacy Study of Abraxane in Combination With Carboplatin to Treat Advanced NSCL Cancer in the ElderlyStudy comparing two regimens of nab-paclitaxel and carboplatin combination in elderly subjects (≥ 70 years old) with advanced NSCLCNCT02151149·Tucson, Arizona and 54 others

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Data from ClinicalTrials.govTerms

TerminatedSurgery With or Without Internal Radiation Therapy Compared With Stereotactic Body Radiation Therapy in Treating Patients With High-Risk Stage I Non-Small Cell Lung CancerRATIONALE: Surgery with or without internal radiation therapy may be an effective treatment for non-small cell lung cancer.NCT01336894·Birmingham, Alabama and 52 others

CompletedUnderstanding Evidence-Based Practice Patterns in Advanced NSCLCThe overarching objective of this study is to close clinical knowledge and performance gaps by providing oncology clinicians with the latest advances and emerging research in the…NCT03107156·Philadelphia, Pennsylvania

TerminatedSerial [18F]Thymidine (FLT)PET/CT as a Biomarker of Response in Pemetrexed Therapy for Non-Small Cell Lung CancerThe investigators will test the hypothesis that positron emission tomography (PET) imaging with the imaging agent 18F-thymidine (FLT) can rapidly assess treatment response in…NCT02274038·Philadelphia, Pennsylvania

TerminatedPolyglutamate Paclitaxel Compared With Docetaxel in Treating Patients With Progressive Non-Small Cell Lung CancerRATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die.NCT00054184·Hoover, Alabama and 34 others

RecruitingFirst-In-Human Study of STX-721/PFL-721 in Participants With Locally Advanced or Metastatic Non-Small Cell Lung Cancer Harboring EGFR or HER2 Exon 20 Insertion MutationsStudy STX-721-101/PFL-721CI101 is an open label, Phase 1/2 study evaluating the safety, tolerability, pharmacokinetic (PK) exposure, and preliminary antitumor activity of…NCT06043817·Duarte, California and 24 others

Active not recruitingA Study of Oral LOXO-292 (Selpercatinib) in Pediatric Participants With Advanced Solid or Primary Central Nervous System (CNS) TumorsThis is an open-label, multi-center Phase 1/2 study of oral LOXO-292 in pediatric participants with an activating rearranged during transfection (RET) alteration and an advanced…NCT03899792·Los Angeles, California and 25 others

RecruitingRadiotherapy to Block Oligoprogression In Metastatic Non-Small-Cell Lung CancerThis study is being done to answer the following question: Can the chance of lung cancer growing or spreading be lowered by adding targeted radiotherapy to the usual combination…NCT06686771·Phoenix, Arizona and 74 others

RecruitingTesting the Addition of High Dose, Targeted Radiation to the Usual Treatment for Locally-Advanced Inoperable Non-Small Cell Lung CancerThis phase III trial compares the effect of adding stereotactic body radiation therapy (SBRT) to the usual treatment (conventional image guided radiation therapy \[IGRT\] and…NCT05624996·Birmingham, Alabama and 476 others

CompletedNelfinavir, Radiation Therapy, Cisplatin, and Etoposide in Treating Patients With Stage III Non-Small Cell Lung Cancer That Cannot Be Removed By SurgeryRATIONALE: Nelfinavir may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth. Radiation therapy uses high energy x-rays to kill tumor cells.NCT00589056·Philadelphia, Pennsylvania

CompletedBortezomib With or Without Docetaxel in Treating Patients With Relapsed or Refractory Advanced Non-Small Cell Lung CancerRATIONALE: Drugs used in chemotherapy such as docetaxel use different ways to stop tumor cells from dividing so they stop growing or die.NCT00064012·Birmingham, Alabama and 20 others

CompletedStudy to Evaluate CCS1477 in Advanced TumoursA Phase 1/2a study to assess the safety, tolerability, PK and biological activity of CCS1477 in patients with metastatic castration resistant prostate cancer, metastatic breast…NCT03568656·Boston, Massachusetts and 18 others

CompletedStudy of Nivolumab (BMS-936558) in Combination With Gemcitabine/Cisplatin, Pemetrexed/Cisplatin, Carboplatin/Paclitaxel, Bevacizumab Maintenance, Erlotinib, Ipilimumab or as Monotherapy in Subjects With Stage IIIB/IV Non-small Cell Lung Cancer (NSCLC) (CheckMate 012)* The study is evaluating the safety and tolerability of Nivolumab (BMS-936558) when combined with three platinum-based doublet chemotherapy regimens (Cisplatin/Gemcitabine…NCT01454102·Los Angeles, California and 11 others

Active not recruitingAssess Efficacy & Safety of Selumetinib in Combination With Docetaxel in Patients Receiving 2nd Line Treatment for v-Ki-ras2 Kirsten Rat Sarcoma Viral Oncogene Homolog (KRAS) Positive NSCLCThe purpose of this study is to assess the efficacy of selumetinib in combination with docetaxel (75mg/m2) vs placebo in combination with docetaxel (75mg/m2) in patients with…NCT01933932·Aurora, Colorado and 196 others

CompletedA Study of XmAb®20717 in Subjects With Selected Advanced Solid TumorsThis is a Phase 1, multiple dose, ascending dose escalation study to define a MTD/RD and regimen of XmAb20717, to describe safety and tolerability, to assess PK and…NCT03517488·Los Angeles, California and 16 others

Active not recruitingNivolumab After Surgery and Chemotherapy in Treating Patients With Stage IB-IIIA Non-small Cell Lung Cancer (An ALCHEMIST Treatment Trial)This phase III ALCHEMIST treatment trial studies how well nivolumab after surgery and chemotherapy work in treating patients with stage IB-IIIA non-small cell lung cancer.NCT02595944·Birmingham, Alabama and 883 others

CompletedPrinted Education Materials in Patients Who Are Finishing Treatment for Stage I, Stage II, or Stage IIIA Breast Cancer, Colorectal Cancer, Prostate Cancer, or Chest CancerRATIONALE: Printed educational materials, such as the Facing Forward Series: Life After Cancer Treatment manual, may help make the transition from cancer patient to cancer…NCT00372840·Philadelphia, Pennsylvania

RecruitingA Study of IDE892 as Monotherapy and Combination in MTAP-deleted Advanced Solid TumorsThis is a multicenter clinical study to evaluate the safety, efficacy, and Pharmacokinetics (PK) of IDE892 as monotherapy and in combination with other agents including IDE397 in…NCT07277413·Goodyear, Arizona and 22 others

RecruitingThe Evaluation of PC14586 in Patients With Advanced Solid Tumors Harboring a TP53 Y220C Mutation (PYNNACLE)The Phase 2 monotherapy portion of this study is currently enrolling and will evaluate the efficacy and safety of PC14586 (INN rezatapopt) in participants with locally advanced or…NCT04585750·Irvine, California and 75 others

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Other Conditions in Philadelphia

Breast Cancer Prostate Cancer Colorectal Cancer Melanoma Leukemia Lymphoma