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Clareo Health | Lung Cancer Clinical Trials in Philadelphia | 480 Studies

Clinical Trials Lung CancerPhiladelphia

Lung Cancer Clinical Trials in Philadelphia

Find 480 clinical trials for lung cancer near Philadelphia, Pennsylvania. Connect with research centers in your area.

All Lung Cancer trials nationwide All trials in Philadelphia

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RecruitingNot yet recruitingActive, not recruitingEnrolling by invitationCompletedTerminated

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Early phase 1Phase 1Phase 1–2Phase 2Phase 2–3Phase 3Phase 4No phase

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Showing 441-460 of 480 trials

CompletedAn Open-Label, Randomized, Phase 3 Trial of Nivolumab Versus Investigator's Choice Chemotherapy as First-Line Therapy for Stage IV or Recurrent PD-L1+ Non-Small Cell Lung Cancer (CheckMate 026)The purpose of this study is to show that Nivolumab will improve progression free survival in subjects with strongly Stage IV or Recurrent PD-L1+ non-small cell lung cancer when…NCT02041533·Mobile, Alabama and 140 others

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Data from ClinicalTrials.govTerms

TerminatedEvaluate BL-M17D1 in Patients w/HER2-Expressing/Mutant Advanced or Metastatic Solid TumorsThe objective of this study to evaluate the safety, tolerability, pharmacokinetics, and efficacy of BL-M17D1 in patients with HER2-Expressing or HER2-Mutant Advanced or Metastatic…NCT06714617·Denver, Colorado and 8 others

RecruitingTocilizumab and Atezolizumab in Adults With Locally Advanced or Metastatic Non-Small Cell Lung Cancer Refractory to 1st Line Immune Checkpoint Inhibitor-Based TherapyThis is a research study to evaluate the safety and effectiveness of tocilizumab in combination with atezolizumab to treat non-small cell lung cancer.NCT04691817·Philadelphia, Pennsylvania

CompletedTrastuzumab Plus Chemotherapy in Treating Patients With Advanced Non-small Cell Lung CancerRATIONALE: Monoclonal antibodies can locate tumor cells and either kill them or deliver tumor-killing substances to them without harming normal cells.NCT00003881·Scottsdale, Arizona and 70 others

CompletedS0702: Osteonecrosis of the Jaw in Patients With Cancer Receiving Zoledronic Acid for Bone MetastasesRATIONALE: Gathering information about how often osteonecrosis of the jaw occurs in patients receiving zoledronic acid for bone metastases may help doctors learn more about the…NCT00874211·Anniston, Alabama and 452 others

Active not recruitingPhase II Randomized Trial of Carboplatin+Pemetrexed+Bevacizumab+/- Atezolizumab in Stage IV NSCLCWhile cigarette smoking remains the primary cause of most lung cancer cases, lung carcinoma in never smokers account for nearly 20 percent of cases.NCT03786692·Philadelphia, Pennsylvania

CompletedStudy of Bevacizumab and Erlotinib in Patients With Advanced Non-small Cell Lung CancerThis study will evaluate the combination of bevacizumab and erlotinib in elderly patients with advanced non-small cell lung cancer.NCT00553800·Galloway, New Jersey and 6 others

CompletedPembrolizumab, Paclitaxel, Carboplatin, and Radiation Therapy in Treating Patients With Stage II-IIIB Non-Small Cell Lung CancerThis phase I trial studies the side effects, best dose, and best way to give pembrolizumab when given together with paclitaxel, carboplatin, and radiation therapy in treating…NCT02621398·New Haven, Connecticut and 2 others

CompletedNivolumab, Cabozantinib S-Malate, and Ipilimumab in Treating Patients With Recurrent Stage IV Non-small Cell Lung CancerThis partially randomized phase II trial studies how well nivolumab, cabozantinib s-malate, and ipilimumab work in treating patients with stage IV non-small cell lung cancer that…NCT03468985·Anchorage, Alaska and 467 others

CompletedA Study of Chemotherapy and Ramucirumab Versus Chemotherapy Alone in Second Line Non-Small Cell Lung Cancer (NSCLC) Participants Who Received Prior First Line Platinum-based ChemotherapyThe purpose of the study is to compare the survival of participants who receive chemotherapy and ramucirumab versus chemotherapy alone as second line treatment for NSCLC after…NCT01168973·Phoenix, Arizona and 230 others

RecruitingA Study to Evaluate INCB161734 in Participants With Advanced or Metastatic Solid Tumors With KRAS G12D MutationThis study is conducted to determine the safety and tolerability of INCB161734 as a single agent or in combination with other anticancer therapies.NCT06179160·Phoenix, Arizona and 33 others

CompletedThe Detection Of Circulating Tumor Cells (CTC) In Patients With NSCLC Undergoing Definitive Radiotherapy Or ChemoradiotherapyCTC levels collected pre-surgery will be correlated with pathological samples.NCT02135679·Philadelphia, Pennsylvania

TerminatedBempegaldesleukin and Pembrolizumab With or Without Chemotherapy in Locally Advanced or Metastatic Solid TumorsThis study is to assess the safety and tolerability, and to assess the preliminary clinical benefit of NKTR-214 when combined with pembrolizumab (KEYTRUDA®) with or without…NCT03138889·Fayetteville, Arkansas and 37 others

TerminatedTivantinib Plus Erlotinib Versus Placebo Plus Erlotinib for the Treatment of Non-squamous, Non-small-cell Lung CancerThis study is to determine if the combination regimen of tivantinib with erlotinib will improve overall survival relative to erlotinib alone in subjects with locally advanced or…NCT01244191·Tucson, Arizona and 303 others

TerminatedEF5 and Motexafin Lutetium in Detecting Tumor Cells in Patients With Abdominal or Non-Small Cell Lung CancerThis clinical trial is studying the amount of EF5 and motexafin lutetium present in tumor cells and/or normal tissues of patients with abdominal (such as ovarian, colon, or…NCT00087191·Philadelphia, Pennsylvania

CompletedChemotherapy, Amifostine, and Radiation Therapy in Treating Patients With Non-small Cell Lung CancerRATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die.NCT00003089·Philadelphia, Pennsylvania

CompletedA Study of CDX-1140 (CD40) as Monotherapy or in Combination in Patients With Advanced MalignanciesThis is a study to determine the maximum tolerated dose (MTD) for CDX-1140 (CD40 antibody), either alone or in combination with CDX-301 (FLT3L), pembrolizumab, or chemotherapy and…NCT03329950·Scottsdale, Arizona and 10 others

TerminatedMulticenter Study of Rociletinib Administered to Patients With Previously Treated Mutant EGFR Non-small Cell Lung CancerThe purpose of this study is to evaluate the safety and anti-tumor effect of rociletinib.NCT02147990·Alhambra, California and 90 others

CompletedChemotherapy and Radiation Therapy With or Without Metformin Hydrochloride in Treating Patients With Stage III Non-small Cell Lung CancerThis randomized phase II trial studies how well chemotherapy and radiation therapy given with or without metformin hydrochloride works in treating patients with stage III…NCT02186847·Tuscaloosa, Alabama and 222 others

TerminatedStudy CB-839 in Combination With Nivolumab in Patients With Melanoma, Clear Cell Renal Cell Carcinoma (ccRCC) and Non-Small Cell Lung Cancer (NSCLC)This study is an open-label Phase 1/2 evaluation of CB-839 in combination with nivolumab in participants with clear cell renal cell carcinoma, melanoma, and non-small cell lung…NCT02771626·Scottsdale, Arizona and 16 others

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Other Conditions in Philadelphia

Breast Cancer Prostate Cancer Colorectal Cancer Melanoma Leukemia Lymphoma