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Clinical TrialsLung Cancer

Lung Cancer Clinical Trials

Browse 8,028 clinical trials for lung cancer. Find studies that match your criteria and connect with research centers.

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Showing 1-20 of 8,028 trials

CompletedA Study to Assess Safety of Nivolumab in Routine Oncology Practice in ChinaThe purpose of this study is to assess the safety of nivolumab in routine cancer practice in China.NCT04825873·Beijing, Beijing Municipality and 1 other CompletedMEK Inhibitor and Thoracic Radiotherapy TrialTwo thirds of non small cell lung cancer patients present with locally advanced tumours (stage III) or metastatic disease (stage IV) and radiotherapy plays a major role in their…NCT01146756·Manchester, Greater Manchester

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Data from ClinicalTrials.govTerms

CompletedTrial of PI-88 With Docetaxel in Advanced Non-Small-Cell Lung Cancer (NSCLC)PI-88 is a new experimental drug that inhibits tumour growth by reducing the formation of new blood vessels into tumours.NCT00097851·Camperdown, New South Wales and 12 others

CompletedDisease Characteristics, Treatment Patterns and Clinical Outcomes in Patients With Newly Diagnosed Unresectable Stage IIIB/IV Non-Small Cell Lung Cancer (NSCLC) in ChinaThe purpose of this observational study is to describe patient and disease characteristics as well as treatment patterns in Chinese patients with unresectable stage IIIB or IV…NCT02458651·Beijing and 10 others

CompletedPembrolizumab/Vibostolimab Coformulation (MK-7684A) or Pembrolizumab/Vibostolimab Coformulation Plus Docetaxel Versus Docetaxel for Metastatic Non Small Cell Lung Cancer (NSCLC) With Progressive Disease After Platinum Doublet Chemotherapy and Immunotherapy (MK-7684A-002, KEYVIBE-002)The main purpose of this study is to compare pembrolizumab/vibostolimab coformulation (MK-7684A) plus docetaxel or pembrolizumab/vibostolimab coformulation to normal saline…NCT04725188·Los Angeles, California and 94 others

CompletedEvaluate the Impact of Afatinib on Quality of Life and Symptom Burden of Greek Subjects With Advanced NSCLC in Routine Patient Care SettingsThis non-interventional study will include a representative sample of patients with locally advanced or metastatic NSCLC harboring Epidermal Growth Factor Receptor…NCT02440854·Alexandroupoli and 6 others

Active not recruitingSacituzumab Tirumotecan (MK-2870) Versus Pemetrexed and Carboplatin Combination Therapy in Participants With Epidermal Growth Factor (EGFR)-Mutated, Advanced Nonsquamous Non-small Cell Lung Cancer (NSCLC) Who Have Progressed on Prior EGFR Tyrosine Kinase Inhibitors (MK-2870-009)The purpose of this study is to evaluate sacituzumab tirumotecan versus pemetrexed in combination with carboplatin for the treatment of epidermal growth factor receptor…NCT06305754·Oakland, California and 155 others

Active not recruitingA Study to Evaluate First-line Ipilimumab + Nivolumab in Patients With Locally Advanced or Metastatic Non-Small Cell Lung CancerThe purpose of this study is to collect and evaluate real-world data to describe the outcomes, patient characteristics, safety profile and treatment patterns of first-line…NCT06487156·Naples

RecruitingObservation or Upfront Cranial RT in Oncogene Mutated NSCLC With Asymptomatic BM: A Phase III RCTTyrosine Kinase Inhibitors (TKIs) especially higher generation TKI have higher CNS penetration rates and have shown favorable response rates in brain metastases.NCT05236946·Mumbai, Maharashtra

TerminatedRidaforolimus With Cetuximab: Adv Non-Small Cell Lung, Colorectal, Head & Neck CancerThe main purpose of this study is to evaluate the best dose, safety and side effects of ridaforolimus when given with cetuximab for patients with head and neck, lung and colon…NCT01212627·Pawtucket, Rhode Island and 1 other

TerminatedA Study Evaluating RO5479599 in Combination With Carboplatin and Paclitaxel in Participants With Advanced or Metastatic Non-Small-Cell Lung Cancer (NSCLC) of Squamous HistologyA multi-center Phase Ib/II study of the combination of RO5479599 with carboplatin and paclitaxel once in every 3 week (q3w) regimen to evaluate the safety and tolerability.NCT02204345·Toronto, Ontario and 5 others

SuspendedAdjuvant ctDNA-Adapted Personalized Treatment in Early Stage NSCLC (ADAPT-E)In this study circulating tumor DNA (ctDNA) blood testing is used to detect the residual blood cancer.NCT04585477·Stanford, California

CompletedTemozolomide for Treatment of Brain Metastases From Non-Small Cell Lung Cancer (Study P03247)The purpose of this study is to demonstrate improvement in overall survival for the combination of whole brain radiation therapy (WBRT) plus temozolomide (TMZ) versus WBRT alone.NCT00076856

UnknownLow-dose Radiotherapy Combined With Conventional Fractionated Radiotherapy in Lung Cancer After Immunotherapy ResistancePre-clinical and clinical studies have shown that low-dose radiation therapy has good immune regulatory effects, activates different anti-tumor immune pathways, and regulates…NCT05906329·Jinan, In Shandong Province

CompletedA Study of BIO-11006 in the Treatment of Advanced Non-Small Cell Lung CancerThis Phase 2 is a randomized study in advanced Non-Small Cell lung cancer patients to evaluate safety and efficacy of aerosolized BIO-11006 in conjunction with chemotherapy.NCT03472053·Surat, Gujarat and 10 others

Active not recruitingCAN-2409 Plus Prodrug With Standard of Care Immune Checkpoint Inhibitor for Stage III/IV NSCLCThe purpose of this clinical trial is to evaluate the effects of adding CAN-2409 + prodrug for stage III/IV NSCLC patients who are on standard of care first line immune checkpoint…NCT04495153·Phoenix, Arizona and 13 others

UnknownWHENII - Early Response Evaluation With FDG-PET/CT and Liquid Biopsy in Patients With NSCLCResponse evaluation with FDG-PET and free circulating DNA in patients with inoperable lung cancer of non small cell type during first treatment with chemotherapy or immunotherapy.NCT03481101·Copenhagen and 1 other

CompletedFirst-in-Human Study of JNJ-74699157 in Participants With Tumors Harboring the KRAS G12C MutationThe purpose of this study is to determine the maximum tolerated dose (MTD) and recommended Phase 2 dose (RP2D) of JNJ-74699157 in participants with advanced solid tumors harboring…NCT04006301·Sarasota, Florida and 6 others

CompletedAn epidemiOlogy Study to deteRmine the Prevalence of EGFR (Epidermal Growth Factor Receptor) muTations in RUSsian Patients With Advanced NSCLC (Non-Small Cell Lung Cancer).This is a multicentre, non-interventional, prospective study to be carried out in representative oncology departments / institutions in order to determine the prevalence of EGFR…NCT02321046·Khanti-Manskiysk, Russia and 25 others

TerminatedMobile Devices to Detect Early Pneumonitis in Stage III NSCLC Patients on Durvalumab.A study of whether mobile devices can improve the detection of pulmonary AEs (including pneumonitis) in stage III NSCLC patients post-CRT, while on durvalumab.NCT04381494·Long Beach, California and 17 others

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Clareo Health | Lung Cancer Clinical Trials | 8,028 Studies Recruiting