Kidney Disease Clinical Trials

Showing 941-960 of 3,346 trials

A Study of LY3473329 in Participants With Impaired and Normal Renal Function

NCT05778864

The main purpose of this study is to assess the amount of study drug (LY3473329) that reaches the bloodstream and the time it takes for the body to get rid of it when given to participants with renal (kidney) impairment compared to participants with normal renal function. The safety and tolerability of LY3473329 will also be evaluated in these participants. The study will last up to 8 weeks including screening period.

Renal Insufficiency

Eli Lilly and Company47 participantsStarted Mar 2023

Edgewater, Florida, United States • Miami, Florida, United States • Orlando, Florida, United States +1 more locations

WITHDRAWNPhase 2

MRI-Guided Radiation Therapy for the Treatment of Early-Stage Kidney Cancer, the MRI-MARK Trial

NCT04580836

This phase II trial investigates how well MRI-guided stereotactic body radiation therapy works in treating patients with early-stage kidney cancer. Radiation therapy uses high energy radiation to kill tumor cells and shrink tumors. Stereotactic body radiation therapy uses special equipment to position a patient and deliver radiation to tumors with high precision. This method may kill tumor cells with fewer doses over a shorter period and cause less damage to normal tissue. This method of radiation delivery is further refined through the incorporation of a MRI into the radiation machine to create a device known as a MRI linear accelerator. During treatment with MRI linear accelerator, continuous MRI images are obtained to allow for real-time treatment monitoring and the ability to adjust treatment plans if minor deviations in anatomy are noted. Giving MRI-guided stereotactic body radiation therapy may help treat patients with early-stage kidney cancer.

Renal Cell CarcinomaStage I Renal Cell Cancer AJCC v8Stage II Renal Cell Cancer AJCC v8

M.D. Anderson Cancer CenterStarted Aug 2020

Houston, Texas, United States

A Study of LY3473329 in Participants With Impaired and Normal Renal Function

MRI-Guided Radiation Therapy for the Treatment of Early-Stage Kidney Cancer, the MRI-MARK Trial

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