Hypertension Clinical Trials

Showing 3021-3040 of 3,518 trials

Urine Chloride/Creatinine Ratio for Estimation of Urine Sodium

NCT00324883

We plan to assess the accuracy of a new means of estimating urine sodium excretion. We will compare the chloride to creatinine ratio obtained by titrator sticks with urine sodium measured by a standard laboratory. If found to approximate sodium excretion, the titrator sticks could provide a convenient means for doctors and patients to monitor their salt intake.

Hypertension

Weill Medical College of Cornell University81 participantsStarted Mar 2006

New York, New York, United States

TERMINATEDPhase 2

Safety and Efficacy of Brinzolamide/Brimonidine Fixed Combination

NCT00961649

The purpose of this study was to compare the safety and intraocular pressure (IOP)-lowering efficacy of a new fixed combination of brinzolamide/brimonidine (Brinz/Brim) to: * its individual components (Brinz and Brim), and * the concomitant administration of Brinz and Brim (Brinz+Brim).

Open-Angle GlaucomaOcular Hypertension

Alcon Research195 participantsStarted Oct 2009

COMPLETEDPhase 3

Three Month Efficacy/Safety Study With a 3-Month Safety Extension of Brinzolamide 1%/Brimonidine 0.2% vs. Brinzolamide 1% or Brimonidine 0.2%

NCT01297920

The purpose of this study was to evaluate the safety and efficacy of a new ophthalmic suspension (Brinz/Brim) in lowering intraocular pressure (IOP) relative to its individual active components in subjects with open-angle glaucoma and/or ocular hypertension.

Open-Angle GlaucomaOcular Hypertension

Alcon Research1,062 participantsStarted Mar 2011

COMPLETEDPhase 4

The Effect of a Peroxisome Proliferator-activated Receptor (PPAR) Alpha Agonist on Cytochrome P450 (CYP) Monooxygenase Activity in Humans

NCT00872599

The hypothesis is to test to see if the drug fenofibrate will increase important chemicals in the body and specifically in the kidney, help to rid the body of salt by the kidneys, decrease blood pressure and improve insulin sensitivity during high-salt intake in individuals with hypertension.

Hypertension

Vanderbilt University75 participantsStarted Sep 2009

Nashville, Tennessee, United States

Urine Chloride/Creatinine Ratio for Estimation of Urine Sodium

Safety and Efficacy of Brinzolamide/Brimonidine Fixed Combination

Three Month Efficacy/Safety Study With a 3-Month Safety Extension of Brinzolamide 1%/Brimonidine 0.2% vs. Brinzolamide 1% or Brimonidine 0.2%

The Effect of a Peroxisome Proliferator-activated Receptor (PPAR) Alpha Agonist on Cytochrome P450 (CYP) Monooxygenase Activity in Humans

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