Saves the questions and what to expect into your notes, next to the visit they belong to.
Keep this study
Lead
Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
Letter to investigator dated 18 June 2012 that study was to be terminated. Study terminated due to evolved and widespread use of standard of care, relevance of study questioned. No safety reasons or issues.
Age
0–0
Sex
ALL
Healthy volunteers
Not accepted
You may be eligible if
72 hours of age; and \> or = to 34 weeks gestational age.
Persistent Pulmonary Hypertension of the Newborn or Hypoxic respiratory failure associated with:
1. Idiopathic PPHN or
2. Meconium aspiration syndrome or
3. Sepsis or
4. Pneumonia
Oxygenation Index (OI) \>15 and \<60 calculated
You may not be if
Patients already receiving inhaled nitric oxide (iNO) on referral.
Prior or immediate need for full Cardio Pulmonary Resuscitation or Extracorporeal Membrane Oxygenation (ECMO).
Life threatening or lethal congenital anomaly.
Large left to right intracardiac or ductal shunting (diagnosed from echocardiogram on admission to GOSH).
Clinically significant active seizures as per clinical judgment.
Bleeding diathesis as per clinical judgment
Clareo Health | Study To Investigate Safety And Efficacy Of Sildenafil In The Newborns With Persistent Pulmonary Hypertension (PPHN)
