About Pricing FAQs Providers Trials Blog

Login Get started

Finding studies

Your health journey, clearly organized.

Questions? [email protected]

Product

How it works
Pricing
For Providers
Trials

Company

About
Blog
FAQ

Legal

Privacy Policy
Terms of Service

© 2026 Clareo Health. All rights reserved.

Clareo Health | Depression Clinical Trials in Houston | 166 Studies

Clinical Trials DepressionHouston

Depression Clinical Trials in Houston

Find 166 clinical trials for depression near Houston, Texas. Connect with research centers in your area.

All Depression trials nationwide All trials in Houston

Order

Status

RecruitingNot yet recruitingActive, not recruitingEnrolling by invitationCompletedTerminated

Phase

Early phase 1Phase 1Phase 1–2Phase 2Phase 2–3Phase 3Phase 4No phase

Who can join

Healthy volunteers too

Showing 121-140 of 166 trials

CompletedCombination Deplin® and Antidepressant Therapy for a Major Depressive Episode (MDE)- a Retrospective AnalysisThis is a retrospective chart review study to determine if Deplin® 7.5mg-15mg combined with an antidepressant is better than an antidepressant alone in adults with major…NCT01001559·Houston, Texas CompletedA Trial of the Safety and Efficacy of SEP-363856 in the Treatment of Adults With Major Depressive DisorderDemonstrate ability of SEP-363856 to be superior to placebo as an adjunctive therapy to ADT in change from baseline in depressive symptoms (MADRS \& CGI-S) in MDD patients who had…NCT05593029·Birmingham, Alabama and 76 others

Depression Trials in Other Cities

New York Los Angeles Chicago Phoenix Philadelphia San Antonio

Data from ClinicalTrials.govTerms

CompletedLong-term Safety Study of BHV-7000 in Participants With Major Depressive Disorder (MDD)The purpose of this study is to evaluate the long-term safety and tolerability of BHV-7000, in participants with Major Depressive Disorder (MDD).NCT06423781·Chandler, Arizona and 65 others

CompletedA Study of Rapastinel as Adjunctive Therapy in Major Depressive Disorder (RAP-MD-03)This study will evaluate the efficacy, safety, and tolerability of rapastinel 450 milligrams (mg) compared to placebo adjunctive to antidepressant therapy (ADT) in patients with…NCT02943577·Dothan, Alabama and 39 others

CompletedA Study of Rapastinel as Adjunctive Therapy in the Prevention of Relapse in Patients With Major Depressive DisorderThis study will evaluate the efficacy, safety and tolerability of rapastinel 450 milligrams (mg) intravenous (IV) once weekly or once every 2 weeks versus placebo as an adjunctive…NCT02951988·Birmingham, Alabama and 136 others

CompletedDouble-Blind, Placebo-Controlled Trial of Ketamine Therapy in Treatment-Resistant Depression (TRD)This study is looking at the efficacy, durability, safety, and tolerability of multiple single doses of Ketamine vs. active placebo for treating patients with treatment resistant…NCT01920555·Palo Alto, California and 5 others

CompletedStudy to Treat Major Depressive Disorder With a New MedicationThis project is designed to examine the neuronal KCNQ2/3 potassium (K+) channel subtype as a novel treatment target for mood disorders through the administration of the…NCT03043560·New York, New York and 1 other

CompletedA Study of Seltorexant Compared to Quetiapine XR as Adjunctive Therapy to Antidepressants in Adult and Elderly Participants With Major Depressive Disorder With Insomnia Symptoms Who Have Responded Inadequately to Antidepressant TherapyThe purpose of this study is to assess the efficacy of seltorexant compared with quetiapine extended-release (XR) as adjunctive therapy to an antidepressant drug in treatment…NCT04513912·Birmingham, Alabama and 174 others

CompletedA Study of Rapastinel as Adjunctive Therapy in Major Depressive Disorder (RAP-MD-02)This study will evaluate the efficacy, safety, and tolerability of two doses of rapastinel, 225 milligrams (mg) and 450 mg, compared to placebo adjunctive to antidepressant…NCT02943564·Birmingham, Alabama and 65 others

CompletedPhase 2b Study of ALTO-100 in MDDThe purpose of this study is to determine efficacy differences between ALTO-100 and placebo, used either as monotherapy or adjunctively to an antidepressant, related to patient…NCT05712187·Birmingham, Alabama and 33 others

CompletedA Long-Term Study of Aripiprazole in Patients With Major Depressive DisorderThis trial is a 52-week safety study to evaluate the safety of adjunctive aripiprazole in outpatients with major depressive disorder who have experienced an incomplete response to…NCT00095745·Mesa, Arizona and 57 others

CompletedEfficacy and Safety of Quetiapine Fumarate Sustained Release (SEROQUEL SR) in Combination With an Antidepressant in the Treatment of Major Depressive DisordersThe purpose of this study is to evaluate the efficacy of quetiapine SR in combination with an antidepressant versus an antidepressant alone in patients with MDD with inadequate…NCT00326105·Phoenix, Arizona and 55 others

RecruitingSelf Neuro-modulation Therapy for Major Depressive Disorder (MDD) With AnhedoniaThe purpose of this research is to learn more about a new treatment for individuals with Major Depressive Disorder (MDD) with heightened symptoms of anhedonia (i.e. loss of…NCT06982820·Providence, Rhode Island and 2 others

CompletedEEG Biomarkers for Predicting Response to Antidepressant TherapyThe purpose of this study is to evaluate the potential early EEG predictors of an individual's response to treatment with antidepressant medications.NCT00289523·Los Angeles, California and 9 others

CompletedAn Efficacy and Safety Study of Sirukumab in Participants With Major Depressive DisorderThe purpose of this study is to evaluate the efficacy of sirukumab as adjunctive treatment to antidepressant therapy (monoaminergic antidepressant) where sirukumab (administered…NCT02473289·Birmingham, Alabama and 45 others

CompletedStudy to Evaluate Potential Predictors of Relapse in Participants With Major Depressive Disorder (MDD)The purpose of this study is to identify if there are self-reported or objective measures related to mood parameters that can predict near-term relapse (within 1 month or at…NCT02489305·Birmingham, Alabama and 24 others

CompletedEfficacy, Safety, and Tolerability of Levomilnacipran ER in Pediatric Patients (7-17 Years) With Major Depressive DisorderThe objective of this study is to evaluate the efficacy, safety, and tolerability of levomilnacipran compared with placebo in pediatric outpatients (7-17 years) with major…NCT03569475·Little Rock, Arkansas and 50 others

CompletedOpen-Label Study of Duloxetine in the Treatment of Children and Adolescents With Major Depressive DisorderThe primary purpose of your participation in this study is to help answer the following research question, and not to provide you treatment for your condition.NCT00529789·Dothan, Alabama and 21 others

RecruitingZelquistinel or Placebo for the Reduction of Symptoms of Major Depressive DisorderThe goal of this clinical trial is to learn if zelquistinel works to treat depression in adults. It will also learn about the safety of zelquistinel.NCT06547489·Birmingham, Alabama and 33 others

CompletedOptimization of IV Ketamine for Treatment Resistant DepressionExisting treatments for major depressive disorder (MDD) generally take weeks to months to exert their maximal benefit.NCT00768430·New York, New York and 1 other

PreviousPage 7 of 9Next

Other Conditions in Houston

Breast Cancer Lung Cancer Prostate Cancer Colorectal Cancer Melanoma Leukemia