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Clareo Health | Depression Clinical Trials in Houston | 166 Studies

Clinical Trials DepressionHouston

Depression Clinical Trials in Houston

Find 166 clinical trials for depression near Houston, Texas. Connect with research centers in your area.

All Depression trials nationwide All trials in Houston

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RecruitingNot yet recruitingActive, not recruitingEnrolling by invitationCompletedTerminated

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Early phase 1Phase 1Phase 1–2Phase 2Phase 2–3Phase 3Phase 4No phase

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Showing 141-160 of 166 trials

TerminatedA Study to Assess the Efficacy and Safety of REL-1017 as Adjunctive Treatment for Major Depressive Disorder (MDD)This is an outpatient, 2-arm, Phase 3, multicenter, randomized, double-blind, placebo-controlled study to assess the efficacy and safety of REL-1017 once daily (QD) as an…NCT04855747·Homewood, Alabama and 69 others

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Data from ClinicalTrials.govTerms

CompletedEfficacy of Lu AA21004 on Cognitive Dysfunction in Major Depressive DisorderThe purpose of this study is to evaluate the effects of Lu AA21004, once daily (QD), on cognitive dysfunction in patients with major depressive disorder.NCT01564862·Tucson, Arizona and 91 others

RecruitingEvaluation of Efficacy and Safety of Milsaperidone as Adjunctive Therapy in Patients With Major Depressive DisorderThe purpose of this study is to determine the efficacy and safety of milsaperidone compared to placebo as adjunctive therapy in patients with Major Depressive DisorderNCT06830044·Phoenix, Arizona and 52 others

CompletedBrexpiprazole (OPC-34712) as an Adjunctive Treatment in Active Adults, 18 to 35 Years Old, With Major Depressive Disorder Who Are in a School or Work EnvironmentTo investigate the efficacy and safety of flexibly dosed adjunctive brexpiprazole treatment in active adults with MDD, 18 to 35 years old, who are experiencing an inadequate…NCT02013609·Cerritos, California and 23 others

CompletedGoal Achievement After a Change to Vortioxetine in Adults With Major Depressive DisorderThe purpose of this study is to determine the effectiveness of treatment with vortioxetine on participant goal achievement after a change in antidepressant medication for the…NCT02972632·Costa Mesa, California and 24 others

CompletedTrial of Centanafadine Efficacy and Safety as Monotherapy or as Adjunct to SSRI in Adults With Major Depressive DisorderThis is a phase 2, multicenter, randomized, double-blind, placebo-controlled, parallel-arm trial to assess the efficacy, safety, and tolerability of centanafadine once-daily (QD)…NCT05536414·Yuma, Arizona and 61 others

CompletedStudy of the Effectiveness of Valbenazine on Patient- and Clinician-Reported Outcomes in Participants With Tardive DyskinesiaThis study will evaluate the effectiveness of valbenazine on patient- and clinician-reported outcomes assessing health-related quality of life, functioning, and treatment effect…NCT05859698·Bryant, Arkansas and 17 others

RecruitingCortical rTMS as a Treatment for DepressionDepression is a leading cause of disability worldwide with a 19% lifetime prevalence in the United States.NCT05487911·Houston, Texas

TerminatedStudy to Assess the Safety and Effectiveness of NMRA-335140-501This is a 52-week open-label extension (OLE) study that will evaluate the safety, tolerability, and effectiveness of NMRA-335140 in participants with major depressive disorder…NCT06029439·Huntsville, Alabama and 177 others

RecruitingStudy to Assess the Efficacy and Safety of NBI-1065845 as an Adjunctive Treatment in Participants With Major Depressive Disorder (MDD)The study will evaluate the efficacy of NBI-1065845 compared with placebo as an adjunctive treatment in participants with MDD on improving symptoms of depression.NCT06786624·Little Rock, Arkansas and 17 others

RecruitingClinical Assessment of Response in the Treatment of Depression With Daytime Sleepiness Using SolriamfetolCLARITY (Clinical Assessment of Response in the Treatment of Depression with Daytime Sleepiness Using Solriamfetol) is a Phase 3, double-blind, placebo-controlled, multicenter…NCT07484217·Tucson, Arizona and 39 others

TerminatedRandomized, Double-Blind, Placebo-Controlled Trial of REL-1017 as Adjunctive Treatment for MDDA Phase 3, randomized, double-blind, placebo-controlled, multicenter trial of REL-1017 in patients with major depressive disorder (MDD).NCT06011577·Dothan, Alabama and 35 others

CompletedA Comparison of Tolerability and Efficacy of Different Doses of Duloxetine for the Treatment of Major Depressive DisorderThe purpose of this study is to compare the tolerability and efficacy of different doses of duloxetine in patients with major depressive disorder.NCT00191061·Little Rock, Arkansas and 31 others

CompletedStudy to Evaluate the Efficacy and Safety of Once-Weekly Oral NBI-1065846 in the Treatment of Anhedonia in MDDTo evaluate the efficacy of NBI-1065846 compared with placebo on improving symptoms of anhedonia in participants with major depressive disorder (MDD).NCT05165394·Birmingham, Alabama and 22 others

CompletedA Study of Adjunctive Aripiprazole in Participants With Major Depressive DisorderThis trial is a 14 week, randomized, double-blind, placebo controlled study, to assess the safety and efficacy of aripiprazole as adjunctive treatment to an ongoing antidepressant…NCT00095758·Beverly Hills, California and 27 others

CompletedEfficacy and Safety Study of BHV-7000 Monotherapy in Major DepressionThe purpose of this study is to determine the efficacy and safety of BHV-7000 in participants with Major Depressive Disorder (MDD)NCT06419608·Phoenix, Arizona and 61 others

RecruitingStudy of Lumateperone as Adjunctive Therapy in the Treatment of Patients With Major Depressive DisorderThis is a multicenter, randomized, double-blind, placebo-controlled parallel-group, fixed-dose study in patients with a primary diagnosis of MDD according to criteria of the…NCT05850689·Huntsville, Alabama and 68 others

CompletedA Study of Aticaprant as Adjunctive Therapy in Adult Participants With Major Depressive Disorder (MDD) With Moderate-to-severe Anhedonia and Inadequate Response to Current Antidepressant TherapyThe purpose of this study is to evaluate the efficacy of aticaprant compared with placebo as adjunctive therapy to an antidepressant in improving depressive symptoms in adult…NCT05455684·Tucson, Arizona and 119 others

CompletedSPD489 in Adults With Persistent Executive Function Impairments (EFI) and Partial or Full Remission of Recurrent Major Depressive DisorderTo evaluate the efficacy of SPD489 for the treatment of executive function impairments (EFI) when used as an adjunct to stable, standard therapy in the setting of partial or full…NCT00985725·Imperial, California and 32 others

CompletedOpen-Label Treatment With Duloxetine Hydrochloride Once-Daily Dosing for Evaluation of Stabilization Dose in Patients With Major DepressionThe purposes of this study are to determine: The safety of duloxetine and any side effects that might be associated with it.NCT00042562·Carlsbad, California and 22 others

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