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Clareo Health | Depression Clinical Trials in Houston | 166 Studies

Clinical Trials DepressionHouston

Depression Clinical Trials in Houston

Find 166 clinical trials for depression near Houston, Texas. Connect with research centers in your area.

All Depression trials nationwide All trials in Houston

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RecruitingNot yet recruitingActive, not recruitingEnrolling by invitationCompletedTerminated

Phase

Early phase 1Phase 1Phase 1–2Phase 2Phase 2–3Phase 3Phase 4No phase

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Showing 101-120 of 166 trials

Active not recruitingDBS for DepressionThe goal of the study is to address the unmet need of TRD patients by identifying brain networks critical for treating depression and to use next generation precision DBS with…NCT03437928·Dallas, Texas and 1 other CompletedOpen-Label Safety Study of AXS-05 in Subjects With DepressionAn open-label, long-term, safety study of AXS-05 in patients with major depressive disorder (MDD), including treatment resistant depression.NCT04039022·Phoenix, Arizona and 50 others

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Data from ClinicalTrials.govTerms

RecruitingTreatment ResistAnt Depression Subcallosal CingulatE Network DBS (TRANSCEND)The goal of this clinical trial is to evaluate the effectiveness and safety of bilateral stimulation of the subcallosal cingulate white matter (SCCwm) using Deep Brain Stimulation…NCT06423430·Birmingham, Alabama and 25 others

CompletedA Safety, Efficacy and Tolerability Study of SEP-225289To determine the safety, efficacy and tolerability of SEP-225289 in subjects with Major Depressive DisorderNCT00584974·Little Rock, Arkansas and 50 others

CompletedA Study to Assess the Efficacy and Safety of AXS-05 in Subjects With Treatment Resistant Major Depressive DisorderTo evaluate the efficacy and safety of AXS-05 relative to bupropion in subjects with treatment resistant major depressive disorder (MDD).NCT02741791·Phoenix, Arizona and 73 others

CompletedEscitalopram in Adult Patients With Major Depressive DisorderThis is a short-term study to evaluate the efficacy, safety, and tolerability of escitalopram in adult patients (18 to 65 years of age) with moderate to severe depression.NCT00668525·Phoenix, Arizona and 44 others

TerminatedThe UTHealth Ketamine ProjectThe primary objective of this study is to determine the effectiveness of serial infusions of intravenous (IV) ketamine in adults with treatment resistant depression (TRD).NCT02882711·Houston, Texas

CompletedTreatment-Resistant Depression RegistryThis registry will collect information about patients with treatment-resistant depression (TRD) who are currently in a major depressive episode.NCT00320372·Tucson, Arizona and 54 others

CompletedStudy to Evaluate the Effects of Oral NMRA-335140 Versus Placebo in Participants With Major Depressive DisorderThis is a randomized, double blind, placebo controlled, multi-center study to evaluate the effects of NMRA-335140 (formerly BTRX 335140) on symptoms of depression in participants…NCT06029426·Huntsville, Alabama and 63 others

CompletedEfficacy, Safety and Tolerability of Agomelatine in the Treatment of Major Depressive DisorderThis study will assess efficacy, safety and tolerability of agomelatine (AGO178) 25 mg and 50 mg in patients with Major Depressive Disorder (MDD).NCT00411099·Scottsdale, Arizona and 43 others

CompletedSafety and Efficacy Study of Vortioxetine (Lu AA21004) in Adults With Major Depressive DisorderThe purpose of this study is to evaluate the efficacy, safety and tolerability of vortioxetine, once daily (QD), compared with placebo in adults with major depressive disorder.NCT01179516·Little Rock, Arkansas and 60 others

CompletedPD, PK, and Safety of ALTO-203 in Patients With MDDThe goal of this clinical trial is to determine the pharmacodynamic effects of ALTO-203 in patients with MDD in a randomized, placebo-controlled, single-dose crossover treatment…NCT06391593·Tucson, Arizona and 14 others

CompletedStudy Evaluating Desvenlafaxine Succinate Sustained-Release (DVS SR) In The Treatment Of Peri- And Postmenopausal Women With Major Depressive Disorder (DVS 3364)A multicenter, 10-week study to evaluate the efficacy and safety of 50 mg of desvenlafaxine succinate sustained-release formulation (DVS SR) versus placebo in the treatment of…NCT01121484·Birmingham, Alabama and 43 others

CompletedComparative Effectiveness Research Trial for Antidepressant Incomplete and Non-responders With TRDThis is a multi-site, randomized, open-label, effectiveness trial comparing three treatment arms for Major Depressive Disorder (MDD) patients with TRD who are currently on…NCT02977299·Birmingham, Alabama and 12 others

CompletedA Multicenter, Relapse Prevention Study With Levomilnacipran Extended Release (ER) in Participants With Major Depressive DisorderThis study evaluates the efficacy, safety and tolerability of levomilnacipran extended-release (ER) compared with placebo in the prevention of depression relapse in major…NCT02288325·Birmingham, Alabama and 46 others

TerminatedOpen-label Long Term (52 Weeks) Safety and Tolerability of Agomelatine Sublingual Tablets in Major Depressive Disorder (MDD)The study will assess safety and tolerability of 0.5 mg/day and 1 mg/day of sublingual (under the tongue) formulation of agomelatine (AGO178) in patients with Major Depressive…NCT01156415·Birmingham, Alabama and 97 others

CompletedA Placebo- and Paroxetine-controlled Study of the Efficacy, Safety and Tolerability of Agomelatine (25 or 50 mg) in the Treatment of Major Depressive Disorder (MDD)This study will evaluate the efficacy, safety and tolerability of agomelatine 25 mg or 50 mg per day and will compare agomelatine and paroxetine tolerability.NCT00463242·Phoenix, Arizona and 46 others

CompletedLong-term Safety and Tolerability of Cariprazine as an Adjunctive Treatment to Antidepressant Therapy in Patients With Major Depressive DisorderThe objective of this study is to evaluate the long-term safety and tolerability of cariprazine as an adjunctive treatment to antidepressant therapy (ADT) in patients with Major…NCT01838876·Tucson, Arizona and 89 others

CompletedMechanistic Evaluation of Response in TRD (MERIT)To evaluate the relapse prevention of AXS-05 relative to placebo in subjects with treatment resistant depression (TRD).NCT04608396·Little Rock, Arkansas and 19 others

CompletedEfficacy, Safety and Tolerability of Agomelatine in the Prevention of Relapse of Major Depressive DisorderThis study will demonstrate the efficacy of agomelatine (AGO178) 25 mg and 50 mg in the prevention of relapse in patients with Major Depressive Disorder (MDD).NCT00467402·Birmingham, Alabama and 77 others

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