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Clareo Health | Depression Clinical Trials in Houston | 166 Studies

Clinical Trials DepressionHouston

Depression Clinical Trials in Houston

Find 166 clinical trials for depression near Houston, Texas. Connect with research centers in your area.

All Depression trials nationwide All trials in Houston

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RecruitingNot yet recruitingActive, not recruitingEnrolling by invitationCompletedTerminated

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Early phase 1Phase 1Phase 1–2Phase 2Phase 2–3Phase 3Phase 4No phase

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Showing 81-100 of 166 trials

CompletedA Study of the Safety and Efficacy of SP-624 in the Treatment of Adults With Major Depressive DisorderThis is a Phase 2 clinical study evaluating the safety and effectiveness of SP-624 as compared to placebo in the treatment of adults with Major Depressive Disorder.NCT04479852·Phoenix, Arizona and 38 others

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Data from ClinicalTrials.govTerms

CompletedStudy to Evaluate the Efficacy and Safety of Adjunctive Pimavanserin in Major Depressive Disorder (CLARITY)To assess the efficacy of pimavanserin compared to placebo when given adjunctively to a selective serotonin reuptake inhibitor (SSRI)/serotonin-norepinephrine reuptake inhibitor…NCT03018340·Birmingham, Alabama and 35 others

CompletedEfficacy and Safety of Vortioxetine (Lu AA21004) in Treating Adults With Major Depressive DisorderThe purpose of this study is to determine the efficacy and safety of once daily vortioxetine (Lu AA21004) in adults with major depressive disorder.NCT00672958·Birmingham, Alabama and 32 others

RecruitingA Study to Evaluate the Efficacy and Safety of Esketamine for Reduction of Symptoms of Major Depressive DisorderThe purpose of this study is to evaluate how well JNJ-54135419 works (efficacy) in addition to comprehensive standard of care (SoC) in rapidly reducing the symptoms of major…NCT07227454·Birmingham, Alabama and 43 others

CompletedLong-term Safety Study of Rapastinel as Adjunctive Therapy in Patients With Major Depressive DisorderThis study will evaluate the long-term safety and tolerability of rapastinel as an adjunctive to antidepressant therapy (ADT) in patients with major depressive disorder (MDD).NCT03002077·Birmingham, Alabama and 127 others

CompletedGenomics Used to Improve DEpression DecisionsEvaluate the impact of GeneSight Psychotropic on response to psychotropic treatment as judged by the mean change in the 17-item Hamilton Depression (HAM-D17) score from baseline…NCT02109939·Birmingham, Alabama and 60 others

SuspendedPramipexole Versus Escitalopram to Treat Major Depressive Disorder (MDD) and Comorbid MDD With Mild Neurocognitive Disorder (MND) in Persons With HIVA phase II, randomized, open-label, two-arm clinical trial evaluating the safety and efficacy of pramipexole extended release (ER) versus escitalopram for the treatment of major…NCT06705478·Birmingham, Alabama and 40 others

CompletedDepression Study In Elderly PatientsMajor Depressive Disorder (MDD) Study in Elderly OutpatientsNCT00067444·Little Rock, Arkansas and 45 others

TerminatedA Study to Assess the Safety and Effect of TC-5214 in Patients With Major Depressive Disorder.The purpose of this study is to assess the safety and effect of TC-5214 as a single therapy in patients with major depressive disorder who exhibit inadequate response to…NCT01288079·Beverly Hills, California and 62 others

CompletedELEKT-D: Electroconvulsive Therapy (ECT) vs. Ketamine in Patients With Treatment Resistant Depression (TRD)The goal of the study is to conduct a comparative randomized trial of electroconvulsive therapy (ECT) vs. ketamine for patients with treatment resistant depression (TRD) in a real…NCT03113968·New Haven, Connecticut and 4 others

CompletedNeuroStar TMS Therapy System: Utilization and OutcomesThe major objective of this observational study is to describe clinical outcomes of patients receiving treatment with the NeuroStar TMS Therapy system in routine clinical practice.NCT01114477·Phoenix, Arizona and 43 others

CompletedXEN1101 for Major Depressive DisorderThis project is designed to examine the neuronal KCNQ2/3 potassium (K+) channel subtype as a novel treatment target for mood disorders through the administration of the…NCT04827901·New York, New York and 1 other

TerminatedStudy of Adjunctive or Monotherapy Rapastinel Treatment in Patients With Major Depressive Disorder (MDD)Multicenter, open-label, long-term extended access treatment protocol in adult patients with a primary diagnosis of MDD.NCT03668600·Birmingham, Alabama and 73 others

CompletedReal-life Effectiveness of Vortioxetine in DepressionWorldwide Major Depressive Disorder (MDD) has significant negative personal, societal and economic consequences.NCT03555136·Dothan, Alabama and 105 others

CompletedAdaptive Design Study of NEST sTMS in Subjects With Major Depressive DisorderThis is a double-blind, sham controlled, multi-center study to confirm the safety and efficacy of synchronized transcranial magnetic stimulation (sTMS) for the treatment of…NCT03288714·La Jolla, California and 13 others

RecruitingPhase 3 Study of Adjunctive Treatment With Seltorexant in Adult and Elderly Participants With Major Depressive Disorder and Insomnia SymptomsThe purpose of this study is to know how well seltorexant works, and also to evaluate safety and maintenance effect of seltorexant compared with placebo as an adjunctive therapy…NCT06559306·Birmingham, Alabama and 204 others

CompletedA Study of Flexible or Fixed Dose LY2216684 as Adjunctive Treatment for Participants With Major Depressive Disorder Who Have Had a Partial Response to Selective Serotonin Reuptake Inhibitor (SSRI) TreatmentThe purpose of this study is to assess if LY2216684 (flexible dose of 12 to 18 milligrams \[mg\] or fixed dose of 6 mg once daily) is superior to placebo once daily in the…NCT01187407·Birmingham, Alabama and 53 others

CompletedA Study of Vilazodone in Pediatric Patients With Major Depressive DisorderThe purpose of this study is to evaluate the long-term safety and tolerability of vilazodone for the treatment of MDD in pediatric outpatients (7-17 years).NCT02436239·Birmingham, Alabama and 55 others

CompletedBrexpiprazole as Adjunctive Treatment in Patients With Major Depressive Disorder With an Inadequate Response to Antidepressant TreatmentTo evaluate the long-term efficacy and safety of brexpiprazole as an adjunctive treatment to an antidepressant treatment (ADT) for adult patients with Major Depressive Disorder…NCT01838681·Little Rock, Arkansas and 106 others

Active not recruitingSmoking Cessation for Depressed SmokersObjectives: Primary Aim: To conduct a preliminary randomized trial in smokers with current recurrent major depressive disorder (MDD), current MDD with a single episode of 2…NCT00494728·Houston, Texas

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