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1–20 of 660
Completed
Impact of the Novel UC-TREAT Diet on the Gut Microbiome and Its Acceptability in Healthy Adults and Adults With Quiescent Ulcerative Colitis
This will be an open-label dietary intervention study recruiting both healthy adults (≥16y) and adults with quiescent Ulcerative Colitis (UC).
NCT06998277
·
Glasgow
Terminated
Javelin Parp Medley: Avelumab Plus Talazoparib In Locally Advanced Or Metastatic Solid Tumors
Avelumab in combination with talazoparib will be investigated in patients with locally advanced (primary or recurrent) or metastatic solid tumors, including non-small cell lung…
NCT03330405
·
Fayetteville, Arkansas and 65 others
Recruiting
Umbilical Cord Mesenchymal Stem Cell Therapy for Biliary Atresia
Biliary atresia is a progressive liver disease in infants where liver transplantation is often the only long-term option once cirrhosis develops.
NCT07797673
·
Jakarta Pusat, DKI Jakarta
Recruiting
Safety and Efficacy of hUC-MSC for the Treatment of Cartilage Damage in the Knee Joint
Testing the safety and efficacy of MSC from umbilical cord tissue (UC-MSC) for the treatment of cartilage damage in the knee joint
NCT06981741
·
Altenburg and 6 others
Enrolling by invitation
Predictive Efficacy of Fecal Calprotectin Assay by Magnetic Particle Chemiluminescence for Mucosal Healing in Moderate-to-Severe Ulcerative Colitis Patients Undergoing Initial Biologic Therapy（PRECAL）
This is a national prospective, multicenter, observational study. A total of 200 eligible patients will be enrolled from 10 hospitals across the country.
NCT07721441
·
Beijing, Beijing Municipality and 9 others
Unknown
Adipose Mesenchymal Stem Cells (AMSC) for Treatment of Ulcerative Colitis
Ulcerative colitis is a form of inflammatory bowel disease characterized by diffuse inflammation of the colonic mucosa.
NCT03609905
·
Liaocheng, Shandong
Active not recruiting
A Comparative Study of Neoadjuvant Chemotherapy Versus Upfront Radical Surgery for Upper Tract Urothelial Carcinoma
This is a single-center, open-label, non-randomized controlled trial comparing the efficacy and safety of neoadjuvant chemotherapy (NAC) followed by radical surgery versus upfront…
NCT07155044
·
Shanghai, Shanghai Municipality
Not yet recruiting
FAPI PET Imaging - An Exploratory Study
This study is testing a new imaging tracer called \[18F\]FAPI-74 with PET scans.
NCT07705074
·
Baden, Canton of Aargau and 4 others
Recruiting
Using Liquid Biopsy Testing to Identify, Monitor, Predict Recurrence in Urothelial Carcinoma
Application of Multi-Component Liquid Biopsy (ctDNA, utDNA, Exosomes, and Protein Biomarkers in Blood and Urine) for Auxiliary Diagnosis, Therapeutic Response Evaluation, and…
NCT07441499
·
Tianjin
Withdrawn
An Open-Label, Randomized Pilot Study Comparing the Safety of a Single Dose of TNX-1300 to Usual Care (UC) Alone for the Treatment of Signs and Symptoms of Acute Cocaine Intoxication in Male Emergency Department (ED) Subjects
An Open-Label, Randomized Pilot Study Comparing the Safety of a Single Dose of TNX-1300 to Usual Care (UC) Alone for the Treatment of Signs and Symptoms of Acute Cocaine…
NCT04996056
·
Detroit, Michigan and 1 other
Suspended
Use of Autologous, Adult Adipose-Derived Stem/Stromal Cells in Inflammatory Bowel Disease
Inflammatory Bowel Disease (IBD) is a group of inflammatory conditions of the small bowel and colon. Main types include Ulcerative Colitis and Crohn's Disease.
NCT02952131
·
Stevensville, Montana
Not yet recruiting
hucMSCs Exosomes for the Treatment of Active Ulcerative Colitis
To evaluate the safety and efficacy of hUC-MSCs-Exos in the treatment of ulcerative colitis.
NCT06853522
·
Shanghai, Shanghai Municipality
Completed
Oral Etrasimod Versus Placebo for the Treatment of Moderately to Severely Active Ulcerative Colitis in Adult Japanese Participants (ELEVATE UC 40 JAPAN)
The purpose of this study is to determine whether oral etrasimod is a safe and effective treatment in adult Japanese participants with moderately to severely active ulcerative…
NCT04706793
·
Nagoya, Aichi-ken and 37 others
Active not recruiting
Avelumab Program Rollover Study
The main purpose of this study is to monitor the safety and tolerability of avelumab in participants with solid tumors who continue treatment with avelumab under the same…
NCT03815643
·
Scottsdale, Arizona and 103 others
Recruiting
IBD Biomarker Discovery and Validation Platform
The goal of this observational study is to establish a multicenter prospective clinical and biospecimen platform for biomarker discovery and validation in inflammatory bowel…
NCT07686406
·
Guangzhou, Guangdong and 1 other
Recruiting
Imaging Study in Metastatic UC, HR+ and HER2- Breast Cancer, TNBC, and NSCLC
This imaging study aims to assess the feasibility, biodistribution, and dosimetry of the imaging agent in subjects with metastatic UC, HR+ and HER2- breast cancer, TNBC, or NSCLC.
NCT07671092
·
St Leonards, New South Wales and 5 others
Not yet recruiting
Nebulized UC-EVs for Recurrent or Refractory IMIDs With Lung Involvement
Immune-mediated inflammatory diseases (IMIDs) are systemic inflammatory disorders driven by dysregulated immune responses that can affect multiple organs, including the lungs.
NCT07806045
·
Beijing
Recruiting
A Study to Evaluate the Efficacy, Safety, and Pharmacokinetics (PK) of RO7837195 in Participants With Moderately to Severely Active Ulcerative Colitis (UC)
The purpose of this study is to evaluate the efficacy of RO7837195 compared with placebo in participants with moderately to severely active ulcerative colitis for whom prior…
NCT06979336
·
Lancaster, California and 107 others
Enrolling by invitation
Ulcerative Colitis Permeability
Study aim: To investigate whether the values of zonulin and lipopolysaccharide-binding protein (LBP) as biomarkers of intestinal permeability are related to the degree of liver…
NCT07662902
·
Zagreb
Not yet recruiting
Evaluating the Efficacy and Safety of Mirikizumab in Adults Over 60 With Moderate to Severe Crohn's Disease and Ulcerative Colitis
This research study looks at how safe and effective a medicine called Mirikizumab is for treating older adults (aged 60 and above) who have moderate to severe Crohn's disease (CD)…
NCT07059130
·
Lawrence, Massachusetts
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