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Avelumab Program Rollover Study | Clinical Trials | Clareo Health

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Active Not RecruitingPhase 3NCT03815643

Avelumab Program Rollover Study

The main purpose of this study is to monitor the safety and tolerability of avelumab in participants with solid tumors who continue treatment with avelumab under the same treatment regimen as in the p...

Lead sponsor: EMD Serono Research & Development Institute, Inc.•26 U.S. locations•View source on ClinicalTrials.gov

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Sponsors

Lead Sponsor

EMD Serono Research & Development Institute, Inc.

Collaborators

Merck KGaA, Darmstadt, Germany

Age

18 - No limit years

Sex

ALL

Healthy Volunteers

No

Inclusion Criteria

•Participants under enrollment and treatment in an avelumab clinical study under the sponsorship of EMD Serono Research \& Development Institute, Inc. / Merck KGaA, Darmstadt, Germany
•* Merck Serono Co., Ltd (Japan)
•Participants currently enrolled in an avelumab parent study and are on active treatment with avelumab or in long-term survival follow-up after treatment
•Participants on active treatment must agree to continue to use highly effective contraception (that is, methods with a failure rate of less than 1% per year) for both male and female participants if the risk of conception exists

Exclusion Criteria

•Participants who are pregnant or breastfeeding
•Participants still on active treatment: Known hypersensitivity to any of the study intervention ingredients
•Participant has been enrolled in the comparator arm of avelumab parent study
•Participant has been withdrawn from avelumab parent study for any reason
•Any other reason that, in the opinion of the Investigator, precludes the participant from participating in the study

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Data from ClinicalTrials.govLast updated on ClinicalTrials.gov: December 4, 2025Terms

Trial snapshot

StatusACTIVE_NOT_RECRUITING

PhasePHASE3

Enrollment205

Start dateMar 2019

Last updatedDec 4, 2025

Condition

Locations shown

HonorHealth Research Institute

Scottsdale, Arizona

Highlands Oncology Group

Fayetteville, Arkansas

University of California Davis Health System - Comprehensive Cancer Center

Sacramento, California

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Data Source & Attribution

This clinical trial information is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.

ClinicalTrials.gov last update: December 4, 2025Data synced to Clareo: May 25, 2026

Modifications: This data has been reformatted for display purposes. Eligibility criteria have been parsed into inclusion/exclusion sections. Location data has been geocoded to enable distance-based search. For the authoritative and most current information, please visit ClinicalTrials.gov.

Neither the United States Government nor Clareo Health make any warranties regarding the data. Check ClinicalTrials.gov frequently for updates.

View ClinicalTrials.gov Terms and Conditions