Clinical Trials in Seattle

Showing 2341-2360 of 8,049 trials

Closed-loop Spinal Stimulation for Restoration of Upper Extremity Function After Spinal Cord Injury

NCT05267951

The purpose of this study is to assess the efficacy of non-invasive (transcutaneous) closed-loop electrical spinal cord stimulation for recovery of upper limb function (Aim 1) and spasticity (Aim 2) following spinal cord injury.

Spinal Cord Injuries

University of Washington9 participantsStarted Oct 2022

Seattle, Washington, United States

TERMINATEDPhase 2< 1 mile

A Study to Evaluate the Anti-inflammatory Effects of Letermovir (Prevymis) in Adults With Human Immunodeficiency Virus (HIV)-1 and Asymptomatic Cytomegalovirus (CMV) Who Are on Suppressive Antiretroviral Therapy, Plus Its Effect on Chronic Inflammation, HIV Persistence and Other Clinical Outcomes.

NCT04840199

This was an open-label, controlled study, conducted at US sites to evaluate the anti-inflammatory effectiveness of the study drug letermovir in adults with HIV and asymptomatic cytomegalovirus (CMV) who were on antiretroviral therapy (ART)-mediated suppression. Participants were randomly assigned to receive either letermovir once daily or no anti-CMV treatment, for 48 weeks. The primary hypothesis of this study was that letermovir would cause a greater reduction in plasma soluble receptor for tumor necrosis factor type II (sTNFRII) levels than no anti-CMV treatment at weeks 46/48.

HIV InfectionsCytomegalovirusCMV

National Institute of Allergy and Infectious Diseases (NIAID)44 participantsStarted Apr 2022

San Diego, California, United States • San Francisco, California, United States • Aurora, Colorado, United States +12 more locations

Closed-loop Spinal Stimulation for Restoration of Upper Extremity Function After Spinal Cord Injury

A Study to Evaluate the Anti-inflammatory Effects of Letermovir (Prevymis) in Adults With Human Immunodeficiency Virus (HIV)-1 and Asymptomatic Cytomegalovirus (CMV) Who Are on Suppressive Antiretroviral Therapy, Plus Its Effect on Chronic Inflammation, HIV Persistence and Other Clinical Outcomes.

Find Trials by Condition in Seattle

Lipoic Acid for Progressive Multiple Sclerosis (MS)

Improving BP Control in Diverse Populations Using BP MAP

PROACTIVE-HF IDE Trial Heart Failure NYHA Class III

TAEK-VAC-HerBy Vaccine for Brachyury and HER2 Expressing Cancer

A Phase 2 Study of IW-3300 for the Treatment of Bladder Pain in Subjects With Interstitial Cystitis/Bladder Pain Syndrome

A Study of AK104, a PD-1/CTLA-4 Bispecific Antibody in Subjects With Recurrent/Metastatic Cervical Cancer

Azacitidine and Combination Chemotherapy in Treating Infants With Acute Lymphoblastic Leukemia and KMT2A Gene Rearrangement

Comparison of Chronocort Versus Standard Hydrocortisone Replacement Therapy in Participants Aged 16 Years and Over With Congenital Adrenal Hyperplasia

S1014 Abiraterone Acetate in Treating Patients With Prostate Cancer Who Have Undergone Initial Hormone Therapy

A Trial to Evaluate the Effects of Bifidobacterium Longum NCC3001 on Intestinal and Psychological Symptoms in Subjects With Irritable Bowel Syndrome

Oral EPI-7386 in Patients with Castration-Resistant Prostate Cancer

Safety and Efficacy of Oral GKT137831 in Patient With Type 2 Diabetes and Albuminuria

MGD019 DART® Protein in Unresectable/Metastatic Cancer

Study of Lanreotide Autogel in Non-functioning Entero-pancreatic Endocrine Tumours

EPI-7386 in Combination with Enzalutamide Compared with Enzalutamide Alone in Subjects with MCRPC

A Double-blind Study to Investigate Efficacy and Safety of Buntanetap Compared With Placebo in Participants With Early PD

Hokusai Study in Pediatric Patients With Confirmed Venous Thromboembolism (VTE)

Screening Protocol for Tumor Antigen Expression Profiling and HLA Typing for Eligibility Determination