Clinical Trials in Pittsburgh

Showing 11301-11320 of 21,047 trials

Neuromuscular Electrical Stimulation for Jaw-closing Dystonia

NCT03889704

6 patients with jaw-closing dystonia will be treated with neuromuscular electrical stimulation over 8 weeks. The distance the mouth can be opened voluntarily and the oro-mandibular dystonia questionnaire (OMDQ-25) will be employed to determine whether there is any objective change in jaw opening or evidence of functional improvement.

Muscle Dystonia

Edward Burton2 participantsStarted May 2019

Pittsburgh, Pennsylvania, United States

COMPLETEDPhase 2< 1 mile

Obeticholic Acid (OCA) in Primary Sclerosing Cholangitis (PSC)

NCT02177136

This was a phase 2, double-blind (DB), placebo-controlled trial in participants with primary sclerosing cholangitis to evaluate the effect of obeticholic acid on liver biochemistry, in particular, serum alkaline phosphatase; and, safety. The long-term safety extension (LTSE) phase was conducted to evaluate the safety, tolerability, and efficacy of long-term, open-label use of OCA in participants with PSC who had completed the DB phase of the study.

Primary Sclerosing Cholangitis (PSC)

Intercept Pharmaceuticals77 participantsStarted Feb 2015

Phoenix, Arizona, United States • Phoenix, Arizona, United States • Sacramento, California, United States +33 more locations

Neuromuscular Electrical Stimulation for Jaw-closing Dystonia

Obeticholic Acid (OCA) in Primary Sclerosing Cholangitis (PSC)

Find Trials by Condition in Pittsburgh

A Safety and Efficacy Trial of Multiple Dosing Regimens of ABT-719 for the Prevention of Acute Kidney Injury in Subjects Undergoing High Risk Cardiac Surgery

Efficacy and Safety of Liraglutide in Combination With Metformin Compared to Metformin Alone, in Children and Adolescents With Type 2 Diabetes

A Phase 3 Study of VX-445 Combination Therapy in Cystic Fibrosis (CF) Subjects Heterozygous for F508del and a Gating or Residual Function Mutation (F/G and F/RF Genotypes)

Dysport in Hallux Abducto Valgus (HAV) Phase IIa

SAR650984, Pomalidomide and Dexamethasone in Combination in RRMM Patients

Multicenter Study Of CPX-1 (Irinotecan HCl: Floxuridine) Liposome Injection In Patients With Advanced Colorectal Cancer

Product Performance of a New Silicone Hydrogel Contact Lens

A Study of Elotuzumab in Combination With Pomalidomide and Low Dose Dexamethasone and Elotuzumab in Combination With Nivolumab in Patients With Multiple Myeloma Relapsed or Refractory to Prior Treatment With Lenalidomide.

Temozolomide,Thiotepa and Carboplatin With Autologous Stem Cell Rescue Followed by 13-cis-retinoic Acid in Patients With Recurrent/Refractory Malignant Brain Tumors

Phase I Study to Determine the Maximum Tolerable Dose of BAY94-9343 in Patients With Advanced Solid Tumors.

Functional Epiphora Management Via Different Dacryocystorhinostomy (DCR) Techniques

Efficacy and Tolerability of STI571 (Imatinib Mesylate) for the Treatment of Fibrosis in Participants With Systemic Sclerosis

A Study to Evaluate ABT-126 for the Treatment of Cognitive Deficits in Schizophrenia

Evaluation of Safety and Efficacy of Lumason/SonoVue in Subjects Undergoing Pharmacologic Stress BR1-142

Viable Allograft Supplemented Disc Regeneration in the Treatment of Patients With Low Back Pain

A CD8 Positron Emission Tomography With Computed Tomography (PET/CT) Study Using ⁸⁹Zr Df-IAB22M2C in Patients With Metastatic Melanoma Receiving Bempegaldesleukin (NKTR-214) and Nivolumab

Comparative Effectiveness of Two Treatments for Veterans With PTSD

Long Term Study of Canakinumab (ACZ885) in Patients With Gout