Clinical Trials in Pittsburgh

Showing 6501-6520 of 21,047 trials

Multiple Dosing of Mesenchymal Stromal Cells in Patients With ARDS (COVID-19)

NCT04466098

This is a multi-center, randomized, placebo controlled, interventional phase 2A trial to evaluate the safety profile and potential efficacy of multi-dosing of mesenchymal stromal cells (MSC) for patients with SARS-CoV-2 associated Acute Respiratory Distress Syndrome (ARDS). After informed consent, treatment assignment will be made by computer-generated randomization to administer either MSC or vehicle placebo control with a 2:1 allocation to the MSC: placebo arm.

Acute Respiratory Distress SyndromeARDS (Moderate or Severe)COVID-19 Pneumonia

Masonic Cancer Center, University of Minnesota8 participantsStarted Jul 2020

Minneapolis, Minnesota, United States • Pittsburgh, Pennsylvania, United States

COMPLETEDPhase 2< 1 mile

A 12-Week Placebo-Controlled Study to Investigate the Efficacy, Safety, and Tolerability of RO7017773 in Participants Aged 15-45 Years With Autism Spectrum Disorder (ASD)

NCT04299464

This study will investigate the efficacy, safety, tolerability, and pharmacokinetics of RO7017773 in participants aged 15-45 years who have been diagnosed with ASD with a score of \>/=50 on the Wechsler Abreviated Scale of Intelligence (WASI-II).

Autism Spectrum Disorder (ASD)

Hoffmann-La Roche104 participantsStarted Mar 2021

Phoenix, Arizona, United States • New Haven, Connecticut, United States • Orlando, Florida, United States +18 more locations

Multiple Dosing of Mesenchymal Stromal Cells in Patients With ARDS (COVID-19)

A 12-Week Placebo-Controlled Study to Investigate the Efficacy, Safety, and Tolerability of RO7017773 in Participants Aged 15-45 Years With Autism Spectrum Disorder (ASD)

Find Trials by Condition in Pittsburgh

Study of the Safety and Efficacy of MR-100A-01 in Approximately 1200 Healthy Women for up to 13 Cycles

The PROMISE Study: Duavee in Women With DCIS

Deep Brain Stimulation Effects in Patients With Chronic Refractory Obesity

B244 Topical Spray for the Treatment of Pruritus in Adults With a History of Atopic Dermatitis

PerQseal® Clinical Study

Trial of LAVA-051 in Patients with Relapsed/refractory CLL, MM, or AML

Prospective Research in Infants With Mild Encephalopathy

Intermediate Expanded Access Protocol CNMAu8.EAP04

Efatutazone Dihydrochloride in Treating Patients With Previously Treated Myxoid Liposarcoma That Cannot Be Removed by Surgery

Trilaciclib in Patients Receiving Sacituzumab Govitecan-hziy for Triple Negative Breast Cancer

Multi-Center Study on Performance of the Ponto Implant System Using Minimally Invasive Ponto Surgery (in Adult Patients)

A Phase 1 Study of ADA-011 for Subjects With Advanced Solid Tumors

A Study to Evaluate Molnupiravir (MK-4482; MOV) in Participants With Severe Renal Impairment (MK-4482-003)

A Study to Evaluate Molnupiravir (MK-4482) in Participants With Moderate Hepatic Impairment (MK-4482-016)

Technology Development for Noninvasive Prenatal Genetic Diagnosis Using Whole Fetal Cells From Maternal Peripheral Blood

Efficacy, Safety and Tolerability of the Combination of Tropifexor & Licogliflozin and Each Monotherapy, Compared With Placebo in Adult Patients With NASH and Liver Fibrosis.

RGX-121 Gene Therapy in Children 5 Years of Age and Over With MPS II (Hunter Syndrome)

Islatravir and Methadone Pharmacokinetics (MK-8591-029)