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Clinical Trials in Philadelphia | 20,904 Studies Near You | Clareo Health

Clinical Trials LocationsPhiladelphia

Clinical Trials in Philadelphia

Discover 20,904 clinical trials near Philadelphia, Pennsylvania. Find research studies in your area.

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Showing 19261-19280 of 20,904 trials

TERMINATEDPhase 2/3< 1 mile

Pilot Study of Varenicline (Chantix®) in the Treatment of Friedreich's Ataxia

NCT00803868

The purpose of this study is to determine if varenicline is effective in treating symptoms of Friedreich's ataxia.

Friedreich's Ataxia

University of South Florida28 participantsStarted May 2009

Tampa, Florida, United States • Philadelphia, Pennsylvania, United States

COMPLETEDPhase 3< 1 mile

Safety of Tobramycin Inhalation Powder (TIP) vs Tobramycin Solution for Inhalation in Patients With Cystic Fibrosis

NCT00388505

This study compares the safety of the tobramycin solution for inhalation with the tobramycin dry powder formulation, used with a simple inhaler

Cystic Fibrosis

Novartis Pharmaceuticals517 participantsStarted Feb 2006

Hartford, Connecticut, United States • Atlanta, Georgia, United States • Chicago, Illinois, United States +69 more locations

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Breast Cancerin Philadelphia Lung Cancerin Philadelphia Prostate Cancerin Philadelphia Colorectal Cancerin Philadelphia Melanomain Philadelphia Leukemiain Philadelphia Lymphomain Philadelphia Pancreatic Cancerin Philadelphia Ovarian Cancerin Philadelphia Brain Cancerin Philadelphia

Data from ClinicalTrials.govTerms

COMPLETEDPhase 2< 1 mile

ADX10059 as an add-on Therapy to Proton Pump Inhibitors (PPIs) in Patients With Gastroesophageal Reflux (GERD)

NCT00810485

The purpose of this study is to evaluate the effect of ADX10059 in patients with gastroesophageal reflux disease who are partial responders to proton pump inhibitors

Gastroesophageal Reflux

Addex Pharma S.A.298 participantsStarted Dec 2008

Little Rock, Arizona, United States • Tucson, Arizona, United States • Anaheim, California, United States +37 more locations

COMPLETEDPhase 3< 1 mile

CRESTOR Athero Imaging Head to Head IVUS Study

NCT00620542

A 104-week, randomized, double-blind, parallel group, multi-center Phase IIIb study comparing the effects of treatment with rosuvastatin 40 mg or atorvastatin 80 mg on atherosclerotic disease burden as measured by intravascular ultrasound in patients with coronary artery disease.

Coronary Atherosclerosis

AstraZeneca2,333 participantsStarted Jan 2008

Huntsville, Alabama, United States • Los Angeles, California, United States • Mountain View, California, United States +192 more locations

COMPLETEDNA< 1 mile

Managed Problem Solving to Increase Treatment Adherence in Individuals With HIV

NCT00130273

This study will determine whether a managed problem solving intervention can help patients with HIV better follow their anti-HIV drug regimen and can control HIV better than the standard of care.

University of Pennsylvania180 participantsStarted Jul 2005

Philadelphia, Pennsylvania, United States

COMPLETEDPhase 312 miles

Evaluation of Efficacy, Safety and Tolerability of Targretin Capsules in Patients With Advanced or Metastatic Non-small Cell Lung Cancer

NCT00050960

This study evaluates the use of Targretin capsules (bexarotene) in combination with standard chemotherapy for the treatment of metastatic Non-Small Cell Lung Cancer (NSCLC) in patients who have not yet received chemotherapy for their lung cancer.

Non-small Cell Lung Cancer

Eisai Inc.612 participantsStarted May 2002

Montgomery, Alabama, United States • Tucson, Arizona, United States • Concord, California, United States +151 more locations

UNKNOWN13 miles

"Assessing Barriers to ADA Guideline Adherence"

NCT00503464

This project involves a comprehensive assessment of barriers to diabetes guidelines adherence across 25 practices in the Crozer-Keystone primary care PBRN. A Barrier Assessment Tool (BAT) will be validated to correlate with provider and practice adherence to diabetes care guidelines. The network is part of the Crozer-Keystone Health System located in Delaware County, Pennsylvania, in the southeast quadrant of the Philadelphia metropolitan region.

Agency for Healthcare Research and Quality (AHRQ)Started Sep 2006

Upland, Pennsylvania, United States

COMPLETEDPhase 340 miles

Study of the Effects of Ciclesonide Hydrofluoroalkane (HFA) Nasal Aerosol on Hypothalamic-Pituitary-Adrenal (HPA) Axis

NCT01033825

To demonstrate the effects of ciclesonide applied as a nasal aerosol and ciclesonide aqueous (AQ) nasal spray on hypothalamic-pituitary-adrenal axis.

Perennial Allergic Rhinitis

Sumitomo Pharma America, Inc.310 participantsStarted Jan 2010

Stockbridge, Georgia, United States • North Dartmouth, Massachusetts, United States • Minneappolis, Minnesota, United States +3 more locations

COMPLETEDPhase 375 miles

A Study of Factor XIII Concentrate in Subjects With Congenital Factor XIII Deficiency

NCT00885742

Congenital deficiency of factor XIII (FXIII) is an extremely rare inherited disorder associated with potentially life-threatening bleeding. Factor XIII Concentrate is given to patients whose blood is lacking factor XIII. Factor XIII Concentrate works by assisting blood in the usual clotting process, thereby preventing bleeding. In this study, patients will be treated with FXIII Concentrate (Human) and followed closely to determine that they receive the dose that will best minimize the chance of bruising and bleeding.

Factor XIII Deficiency

CSL Behring41 participantsStarted Aug 2009

Dothan, Alabama, United States • Oakland, California, United States • Orange, California, United States +20 more locations

TERMINATEDPhase 381 miles

Calfactant for Direct Acute Respiratory Distress Syndrome

NCT00682500

This study will determine if administration of an suspension of calfactant, a lung surfactant, intratracheally in patients with Direct Acute Respiratory Distress Syndrome within 48 hours of requiring mechanical ventilation can decrease the mortality in patients with lethal disease and shorten the course of respiratory failure in patients with sub-lethal disease.

Respiratory Distress Syndrome, Adult

Pneuma Pharmaceuticals Incorporated332 participantsStarted May 2008

Gainesville, Florida, United States • Orlando, Florida, United States • Chicago, Illinois, United States +29 more locations

WITHDRAWNNA81 miles

Comparison Study for Safety and Efficacy of Two Devices for the Treatment of the Great Saphenous Vein

NCT01173419

This is a multi center, randomized, comparison study using two already cleared methods of treatment of the great saphenous vein (GSV). The hypothesis to be tested is that the use of the Venacure EVLT NeverTouch procedure is no worse than the RF ClosureFAST procedure for treatment of the GSV. Evaluation of post operative pain and bruising, quality of life assessments, adverse event assessments, confirmation of long term GSV closure, use of medications are criteria that will be evaluated during the course of this study.

Varicose VeinsVenous Insufficiency

Angiodynamics, Inc.Started Jul 2010

Sacramento, California, United States • Bradenton, Florida, United States • Melrose Park, Illinois, United States +3 more locations

COMPLETEDPhase 381 miles

Peripheral Facilitated Antegrade Steering Technique in Chronic Total Occlusions

NCT01246505

Study of the BridgePoint Medical System in the crossing of chronic total occlusions of the lower extremities.

Chronic Total Occlusion

BridgePoint Medical105 participantsStarted Jul 2011

Phoenix, Arizona, United States • Los Angeles, California, United States • Torrance, California, United States +7 more locations

COMPLETEDPhase 190 miles

Safety and Tolerability Study to Evaluate MEDI-534 in Children 6 to < 24 Months of Age

NCT00493285

The overall objective of the MEDI-534 clinical development program is to evaluate the safety, efficacy and tolerability of MEDI-534 for the prevention of serious RSV and PIV3 disease in young infants.

Respiratory Viral InfectionsRespiratory Syncytial Virus InfectionsParainfluenza Virus 3, Human

MedImmune LLC49 participantsStarted Jul 2007

Conway, Arkansas, United States • Little Rock, Arkansas, United States • Aurora, Colorado, United States +27 more locations

COMPLETEDPhase 397 miles

Evaluation of Clinical Endpoints of Two Diclofenac Sodium Gel 1%

NCT01456611

The objective of this study is to evaluate the clinical equivalence and safety of the Test formulation of diclofenac sodium topical gel 1% (Anchen Pharmaceuticals, Inc.) compared to the marketed formulation Voltaren® Gel (diclofenac sodium topical gel) 1% (Novartis) in patients with osteoarthritis of the knee. The efficacy of both the Test and Reference formulations will also be compared to the Placebo gel to determine Superiority.

Osteo Arthritis of the Knee

Anchen Pharmaceuticals, Inc749 participantsStarted Sep 2011

Birmingham, Alabama, United States • Huntsville, Alabama, United States • Chandler, Arizona, United States +54 more locations

COMPLETEDPhase 397 miles

Study Of Gemcitabine Plus AG-013736 Versus Gemcitabine For Advanced Pancreatic Cancer.

NCT00471146

The purpose of this study is to determine whether investigational study drug, AG-013736, and gemcitabine are effective in the first-line treatment of advanced pancreatic cancer.

Carcinoma, Pancreatic Ductal

Pfizer630 participantsStarted Jul 2007

Antioch, California, United States • Corona, California, United States • Glendora, California, United States +201 more locations

COMPLETEDPhase 1/2200 miles

Safety Study Using Weekly Infusions of BB-10901 in Patients With Small Cell Lung Cancer

NCT00065429

This study was a Phase I/II trial primarily focused on efficacy of BB-10901 in relapsed small cell lung cancer and other solid tumors.

Small Cell Lung Cancer

ImmunoGen, Inc.64 participantsStarted Apr 2003

Denver, Colorado, United States • Ocoee, Florida, United States • Springfield, Massachusetts, United States +8 more locations

COMPLETEDPhase 3332 miles

Cisplatin With or Without Raltitrexed in Treating Patients With Malignant Mesothelioma of the Pleura

NCT00004920

RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. It is not yet known whether receiving cisplatin with raltitrexed is more effective than cisplatin alone for malignant mesothelioma. PURPOSE: Randomized phase III trial to compare the effectiveness of cisplatin with or without raltitrexed in treating patients who have malignant mesothelioma of the pleura.

Malignant Mesothelioma

European Organisation for Research and Treatment of Cancer - EORTC256 participantsStarted Nov 1999

Leuven, Belgium • Hamilton, Ontario, Canada • London, Ontario, Canada +23 more locations

COMPLETEDPhase 1332 miles

Multiple Dose Study In Cancer Patients: Safety and Tolerability of BMS-754807 in Combination With Paclitaxel and Carboplatin in Patients With Advanced or Metastatic Solid Tumors

NCT00793897

A Phase I dose escalation study to determine the safety, tolerability, pharmacodynamics and preliminary anti-tumor activity of BMS-754807 in combination with chemotherapy drugs, paclitaxel and carboplatin, in patients with advanced or metastatic solid tumors. In addition, the study is expected to identify the recommended dose or dose range of BMS-754807 in combination with paclitaxel and carboplatin for Phase 2 studies

Advanced Solid TumorsMetastatic Solid Tumors

Bristol-Myers Squibb21 participantsStarted Apr 2009

East Melbourne, Victoria, Australia • Parville, Victoria, Australia • Edmonton, Alberta, Canada +2 more locations

COMPLETEDPhase 1/2339 miles

Combination Study of BMS-754807 and Herceptin® in Patients With Advanced or Metastatic Her-2-positive Breast Cancer

NCT00788333

This is a Phase I/II study to evaluate the safety profile, tolerability, pharmacokinetics and pharmacodynamics following daily oral doses of 50 to 200 mg of BMS-754807 in combination with trastuzumab (Herceptin®) in subjects with advanced or metastatic Her-2-positive breast cancer. In addition, the study is expected to identify the recommended dose or dose range of BMS-754807 in combination with trastuzumab for Phase II studies and provide preliminary evidence of anti-tumor activity in Her-2-positive breast cancer subjects after trastuzumab failure

Bristol-Myers Squibb40 participantsStarted Jul 2009

Kurralta Park, South Australia, Australia • Frankston, Victoria, Australia • Geelong, Victoria, Australia +6 more locations

COMPLETEDPhase 1993 miles

Study of the Safety & PK of INX-08189 in Chronically-infected HCV, Treatment-naïve Subjects

NCT01250366

The purpose of this study is to determine the Safety and Pharmacokinetics of Multiple Ascending Oral Doses of INX-08189 in Chronically-infected Genotype 1 HCV, Treatment-naïve Subjects.

HCV (Genotype 1)

Bristol-Myers Squibb70 participantsStarted Oct 2010

Los Angeles, California, United States • Plymouth, Minnesota, United States • San Antonio, Texas, United States +1 more locations

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