Clinical Trials in Philadelphia

Showing 13701-13720 of 20,904 trials

Safety and Efficacy of CEM-102 With Rifampin Compared to Standard Therapy in Patients With Prosthetic Joint Infections or Spacer Infection

NCT01756924

To determine if oral antibiotic treatment with CEM-102 and Rifampin is as effective and safe as the standard of care antibiotic therapy for the treatment of hip and knee prosthetic joint or spacer infections

Prosthetic Joint Infections of HipProsthetic Joint Infections of KneeInfected Spacers

Arrevus Inc.14 participantsStarted Dec 2012

Sarasota, Florida, United States • Tamarac, Florida, United States • Savannah, Georgia, United States +10 more locations

COMPLETEDPhase 1/2< 1 mile

FOLFOX/Bevacizumab/Hydroxychloroquine (HCQ) in Colorectal Cancer

NCT01206530

In this Phase I/II clinical trial, the investigators seek to pilot the addition of hydroxychloroquine (HCQ) to the standard front-line therapy of colorectal cancer, FOLFOX/bevacizumab. In toxicity terms, the investigators previous studies lead them to believe that a full dose (800mg) of HCQ will be well-tolerated in this setting. By starting at 600 mg, the investigators will ensure that the full dose is approached with an eye to safety, and if needed, the investigators will use the lower dose. Both doses achieve autophagy inhibition in our current studies.

Rectal CancerColon CancerMetastasis+1 more

Abramson Cancer Center at Penn Medicine50 participantsStarted Sep 2010

Philadelphia, Pennsylvania, United States

Safety and Efficacy of CEM-102 With Rifampin Compared to Standard Therapy in Patients With Prosthetic Joint Infections or Spacer Infection

FOLFOX/Bevacizumab/Hydroxychloroquine (HCQ) in Colorectal Cancer

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Effects of Implicit Messaging by Cigarette Pack Color on Smoking Behaviors

Combination Chemotherapy in Treating Patients With Stage III or Stage IV Ovarian Epithelial Cancer or Primary Peritoneal Cancer

The Effects of Guarding on the Outcomes of the Six Minute Walk Test

24 Week Efficacy and 3-year Safety and Efficacy of Secukinumab in Active Psoriatic Arthritis

EXTEND Exercise Trial

Safety and Efficacy Evaluation of DOTAREM® in MRI of Central Nervous System (CNS) Lesions

Assessment of nanOss Bioactive 3D in the Posterolateral Spine

10003 PRO Current Products

Hybrid Closed Loop Pivotal Trial in Type 1 Diabetes

A Randomized Trial of Effects of Parent Mentors on Insuring Minority Children

Long-Term Patient Satisfaction of Facial Aesthetic Treatment With BOTOX®

Safety and Tolerability of PF-05230907 in Intracerebral Hemorrhage

Clinical Study to Assess the Long-term Safety, Tolerability, and Efficacy of Macitentan in Subjects With Eisenmenger Syndrome

Safety and Efficacy of Entospletinib (ENTO [GS-9973]) Combined With Vincristine (VCR) in Adult Participants With Relapsed or Refractory B-cell Non-Hodgkin Lymphoma (NHL)

Sym004 vs Standard of Care in Subjects With Metastatic Colorectal Cancer

Safety and Efficacy Study of Dexamethasone Versus Ranibizumab in Patients With Diabetic Macular Edema

Evaluation of AGN-150998 in Exudative Age-related Macular Degeneration (AMD)

Pulmonary Tuberculosis Patients With Diabetes Mellitus