Clinical Trials in Philadelphia

Showing 13641-13660 of 20,904 trials

Open-label Extension Study of NEOD001 in Subjects With Light Chain (AL) Amyloidosis

NCT02613182

The rationale for this study is to provide additional treatment with NEOD001 for subjects who complete Study NEOD001-001, and to continue to evaluate long term safety and tolerability. All subjects in the current NEOD001 trials are being dosed at 24 mg/kg, which will be continued in this study.

AL Amyloidosis

Prothena Biosciences Ltd.34 participantsStarted Feb 2016

Stanford, California, United States • Boston, Massachusetts, United States • Detroit, Michigan, United States +2 more locations

COMPLETEDPhase 1< 1 mile

BAY1436032 in Patients With Mutant IDH1(mIDH1) Advanced Acute Myeloid Leukemia (AML)

NCT03127735

To determine the maximum tolerated and / or recommended Phase II dose of oral mutant IDH1 (mIDH1) inhibitor BAY1436032 and to characterize its safety, tolerability, pharmacokinetics, pharmacodynamics, and preliminary clinical efficacy in patients with mIDH1-R132X advanced acute myeloid leukemia (AML)

Leukemia, Myeloid, Acute

Bayer27 participantsStarted Jun 2017

Buffalo, New York, United States • New York, New York, United States • The Bronx, New York, United States +10 more locations

Open-label Extension Study of NEOD001 in Subjects With Light Chain (AL) Amyloidosis

BAY1436032 in Patients With Mutant IDH1(mIDH1) Advanced Acute Myeloid Leukemia (AML)

Find Trials by Condition in Philadelphia

A Study of CK-2017357 in Patients With Amyotrophic Lateral Sclerosis (ALS)

Development of an Algorithm That Predicts Hypoventilation Due to an Opioid Overdose

A Behavioral Economics-Based Telehealth Intervention to Improve Post-MI Medication Adherence

Handheld Vibrator Versus Topical Eye Drops as Anesthesia for Intravitreal Injections

A Study With an Open-label Extension Phase to Evaluate the Effect of Perampanel (E2007) on Cognition, Growth, Safety, Tolerability, and Pharmacokinetics in Adolescents

A 6-month Clinical Study to Evaluate the Effect of a Digital Disease Management Tool in Patients With T2DM

Mobile App With Patient Financial Incentives for Adherence to Heart Failure Medications & Daily Self-Weighing

A Phase 2a, Proof-of-Concept Study of GIC-1001 in the Management of Visceral Pain During Sedation-Free, Full Colonoscopy

A Randomized, Double-Blind, Placebo-Controlled Study of Idelalisib in Combination With Rituximab for Previously Treated Chronic Lymphocytic Leukemia (CLL)

Efficacy and Safety Study of Cenicriviroc for the Treatment of Nonalcoholic Steatohepatitis (NASH) in Adult Participants With Liver Fibrosis

Safety Study of Enzalutamide (MDV3100) in Patients With Incurable Breast Cancer

ST266 Versus Standard Care In Treating Partial Thickness Burns

Fenzian Asthma Multicenter Outcomes Study

AG-013736 In Combination With Gemcitabine Versus Gemcitabine Alone For Patients With Metastatic Pancreatic Cancer

Clinical Study to Evaluate the Safety and Tolerability of Macitentan in Subjects With Combined Pre- and Post-capillary Pulmonary Hypertension (CpcPH) Due to Left Ventricular Dysfunction

A Study for Patients With Acute Leukemia

Risperidone Long-acting Versus Oral Risperidone in Patients With Schizophrenia and Alcohol Use Disorder

BENEFIT 15 Long-term Follow-up Study of the BENEFIT and BENEFIT Follow-up Studies