Clinical Trials in Philadelphia

Showing 12281-12300 of 20,904 trials

Renal AL Amyloid Involvement and NEOD001

NCT03168906

This is a multicenter, Phase 2b, randomized, double-blind, placebo-controlled, two-arm, parallel-group efficacy and safety study of NEOD001 as a single agent administered intravenously in adults with AL amyloidosis who have a maintained hematologic response to their most recent treatment for AL amyloidosis (e.g., chemotherapy, autologous stem cell transplant \[ASCT\]) and have persistent renal dysfunction.

Amyloidosis

Tufts Medical Center12 participantsStarted Jul 2017

Scottsdale, Arizona, United States • San Francisco, California, United States • Jacksonville, Florida, United States +6 more locations

TERMINATEDPhase 2< 1 mile

Cariprazine Effects on Brain and Behavior in Cocaine Use Disorder

NCT03430544

This is a phase II, randomized, single-blind, placebo-controlled study to examine whether cariprazine (1.5 or 3 mg/d) 1) alters brain and/or behavioral responses to probes of reward and inhibition and 2) decreases cocaine use in individuals with cocaine use disorder. Subjects will be tested as inpatients during fMRI sessions. After the 2-week inpatient/medication induction phase, study medication will continue for 8 outpatient weeks, during which time cocaine use will be tracked. Subjects will be monitored during a 4-wk followup phase thereafter.

Cocaine Use Disorder

Anna Rose Childress, Ph.D.14 participantsStarted Apr 2018

Philadelphia, Pennsylvania, United States

Renal AL Amyloid Involvement and NEOD001

Cariprazine Effects on Brain and Behavior in Cocaine Use Disorder

Find Trials by Condition in Philadelphia

A Study of Demcizumab Plus Paclitaxel in Subjects With Platinum Resistant Ovarian

The Effects of Online Single-Session Interventions on College Student Well-being

A Therapeutic Equivalence Study of Two Metronidazole Gel 1% Topical Treatments of Rosacea

Chemoradiation Therapy and Ipilimumab in Treating Patients With Stages IB2-IIB or IIIB-IVA Cervical Cancer

Bringing I-PASS to the Bedside: A Communication Bundle to Improve Patient Safety and Experience

Safety and Efficacy of Levomilnacipran ER in Adolescent Participants With Major Depressive Disorder

Bioequivalence of Generic Imiquimod Cream, 5% When Compared to Aldara™ (Imiquimod) Cream, 5% in the Treatment of Actinic Keratosis

ARMOR1: Study of TOK-001 to Treat Castration Resistant Prostate Cancer

Identification of Herpes Simplex Virus (HSV) Shedding in the Female Genital Tract of Pregnant and Nonpregnant Women by GeneXpert PCR, Routine PCR, and Culture

Phase 2 Trial of Seribantumab Plus Fulvestrant in Postmenopausal Women With Metastatic Breast Cancer

Randomized, Standard-Controlled, Study to Evaluate the Ohana IVF Sperm Preparation Kit, SPeRtility IVF Next Generation

Safety and Efficacy Study of Single Weekly Bortezomib in Newly Diagnosed Multiple Myeloma

A Study of Flortaucipir PET in Healthy Volunteers and Cognitively Impaired Subjects

18F-AV-1451 Autopsy Study

Use of Recombinant Adenovirus Therapy to Treat Localized Prostate Cancer

Defining the HER2 Positive (+) Breast Cancer Kinome Response to Trastuzumab, Pertuzumab, Combination Trastuzumab +Pertuzumab, or Combination Trastuzumab + Lapatinib

A Personal Cancer Vaccine (NEO-PV-01) and APX005M or Ipilimumab With Nivolumab in Patients With Advanced Melanoma

An Efficacy and Safety Trial of Intravenous Zoledronic Acid Twice Yearly in Osteoporotic Children Treated With Glucocorticoids