Clinical Trials in Philadelphia

Showing 3881-3900 of 20,904 trials

Educational Video for Genetic Testing

NCT05472714

Develop and evaluate the acceptability, feasibility, and preliminary efficacy of an informational video on paired tumor/normal testing for children and adolescents with a new diagnosis of cancer, tumors or other diagnosis.

Genetic DiseaseCancer

Children's Hospital of Philadelphia355 participantsStarted Sep 2021

Philadelphia, Pennsylvania, United States

Active Not RecruitingPhase 2< 1 mile

Testing Crizotinib as a Potential Targeted Treatment in Cancers With ALK Genetic Changes (MATCH-Subprotocol F)

NCT04439266

This phase II MATCH treatment trial identifies the effects of crizotinib in patients whose cancer has a genetic change called ALK rearrangement. Crizotinib may stop the growth of cancer cells by blocking the ALK protein which may be needed for cell growth. Researchers hope to learn if crizotinib will shrink this type of cancer or stop its growth.

Advanced LymphomaAdvanced Malignant Solid NeoplasmHematopoietic and Lymphoid Cell Neoplasm+3 more

National Cancer Institute (NCI)5 participantsStarted Aug 2015

Philadelphia, Pennsylvania, United States

Active Not Recruiting< 1 mile

Natural History Study Protocol in PMM2-CDG (CDG-Ia)

NCT03173300

Clinical and Basic Investigations into Phosphomannomutase deficiency (PMM2-CDG) This is a natural history (observational) protocol designed to collect clinical and biological information in patients with PMM2-CDG (CDG-Ia).

Phosphomannomutase 2 Deficiency

Glycomine, Inc.120 participantsStarted Jan 2018

Rochester, Minnesota, United States • Philadelphia, Pennsylvania, United States • Seattle, Washington, United States +8 more locations

Educational Video for Genetic Testing

Testing Crizotinib as a Potential Targeted Treatment in Cancers With ALK Genetic Changes (MATCH-Subprotocol F)

Natural History Study Protocol in PMM2-CDG (CDG-Ia)

Find Trials by Condition in Philadelphia

Safety, Reactogenicity and Immunogenicity of HB-502 and HB-501 Versus Placebo in People With HIV on Suppressive ART

Beta-blocker Administration for Cardiomyocyte Division

Study to Assess the Effect of Long-term Treatment With Voxelotor in Participants Who Have Completed Treatment in Study GBT440-031

A Study of BMS-986249 Alone and in Combination With Nivolumab in Advanced Solid Tumors

Darbepoetin Trial to Improve Red Cell Mass and Neuroprotection in Preterm Infants

AI-informed Colorectal Cancer (CRC) Screening Navigation vs. Standard of Care Among Screening-naive Penn Medicine Patients 45-49 Years Old to Increase CRC Screening Uptake

Supporting Self-Management of Healthy Behaviors in Chronic Kidney Disease

Propensity-Matched Study of Cardiac Contractility Modulation Therapy in Heart Failure

Establishment of ProNephro AKI (NGAL) Cut Off Value for Risk Assessment of Moderate to Severe Acute Kidney Injury in Adults

A Study to Evaluate the Efficacy and Safety of Pemigatinib (INCB054828) in Subjects With Myeloid/Lymphoid Neoplasms With FGFR1 Rearrangement - (FIGHT-203)

Study of TNG260 and an Anti-PD Antibody in STK11 Mutated Solid Tumors

A Study to Evaluate the Pharmacokinetics, Safety, and Tolerability of a New Formulation of Cabotegravir Long-Acting Administered Intramuscularly in a 4-month Dosing Interval (Q4M)

MARGetuximab Or Trastuzumab (MARGOT)

A Switch to Doravirine/Islatravir (DOR/ISL) in Participants With Human Immunodeficiency Virus Type 1 (HIV-1) Who Are Virologically Suppressed on Bictegravir/Emtricitabine/Tenofovir Alafenamide (BIC/FTC/TAF) (MK-8591A-052)

Study of SRP-4045 (Casimersen) and SRP-4053 (Golodirsen) in Participants With Duchenne Muscular Dystrophy (DMD)

Efanesoctocog Alfa Prophylaxis in Patients With Hemophilia A With Synovial Hypertrophy

Clinical Trial of SOT102 Antibody Drug Conjugate in Patients With Advanced Gastric and Pancreatic Adenocarcinoma