Subjects will be assigned to treatment via nasal spray with either GLS-1200 or placebo in blinded manner in a 2:1 ratio. Treatment will commence 1 week post-operatively and continue for 7 weeks.
Age
18–any
Sex
ALL
Healthy volunteers
Not accepted
You may be eligible if
Age 18 years or older;
Able to provide informed consent
Able and willing to comply with study procedures
Elective FESS
Able and willing to utilize an approved form of pregnancy prevention for women of child bearing potential
You may not be if
Pregnancy or documentation of pregnancy by pre-operative pregnancy test
History of primary ciliary dyskinesia
Known allergy to quinine, quinidine or mefloquine
Know latex allergy
History of hematologic malignancy
History of bone marrow transplantation
Current or planned chemotherapy treatment for hematologic or solid tumor during study period
FESS performed non-electively and /or in preparation for decontamination of the sinuses related to cystic fibrosis or in preparation for chemotherapy, solid organ transplantation, or bone marrow transplantation
