Clinical Trials in Ohio

Showing 16621-16640 of 20,938 trials

Pralatrexate and Docetaxel in Treating Patients With Stage IV Esophageal or Gastroesophageal Cancer Who Have Failed Platinum-Based Therapy

NCT01129206

RATIONALE: Pralatrexate may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth. Drugs used in chemotherapy, such as docetaxel, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing. Giving pralatrexate together with docetaxel may kill more tumor cells. PURPOSE: This phase II trial is studying how well giving pralatrexate together with docetaxel works in treating patients with stage IV esophageal or gastroesophageal cancer who have failed platinum-based therapy.

Adenocarcinoma of the EsophagusAdenocarcinomas of the Gastroesophageal JunctionRecurrent Esophageal Cancer+2 more

Ohio State University Comprehensive Cancer Center6 participantsStarted Jul 2010

Columbus, Ohio, United States

TERMINATED32 miles

Cardiac Output Measurement at the Conclusion of Cardiopulmonary Bypass

NCT01103908

Cardiac output, the amount of blood pumped by the heart in one minute, will be measured in pediatric patients undergoing surgery involving cardiopulmonary bypass (CPB). Cardiac output will be measured after cardiopulmonary bypass using a device that employs ultrasound dilution technology. At times, cardiac output will be measured during a procedure called modified ultrafiltration (MUF). The ultrasound dilution cardiac output measurements will be validated or compared with cardiac output measurements made using other FDA approved techniques and devices.

Cardiac Output

Transonic Systems Inc.3 participantsStarted Apr 2010

Columbus, Ohio, United States

COMPLETEDNA32 miles

Vistakon Investigational Contact Lenses Worn for Daily Wear

NCT00717249

This study compares the performance of an investigational contact lens to a currently marketed lens.

Myopia

Johnson & Johnson Vision Care, Inc.529 participantsStarted Aug 2007

Fresno, California, United States • Mission Viejo, California, United States • Louisville, Colorado, United States +17 more locations

Pralatrexate and Docetaxel in Treating Patients With Stage IV Esophageal or Gastroesophageal Cancer Who Have Failed Platinum-Based Therapy

Cardiac Output Measurement at the Conclusion of Cardiopulmonary Bypass

Vistakon Investigational Contact Lenses Worn for Daily Wear

Find Trials by Condition in Ohio

Comparison of TAK-875 to Placebo as an Add-on to Glimepiride in Patients With Type 2 Diabetes

Efficacy and Safety Study of DiaPep277 in Newly Diagnosed Type 1 Diabetes Adults

Risedronate to Prevent Skeletal Related Events in Patients With Metastatic Prostate Cancer Commencing Hormonal Therapy

A Phase 2 Study of Atacicept in Subjects With Relapsing Multiple Sclerosis (ATAMS)

Study to Evaluate the Efficacy and Safety of Armodafinil Treatment (150 mg/Day) as Adjunctive Therapy in Adults With Major Depression Associated With Bipolar I Disorder

Dose Ranging Study of Celivarone With Amiodarone as Calibrator for the Prevention of Implantable Cardioverter Defibrillator (ICD) Interventions or Death

Open-Label Extension Study to Evaluate Long Term Safety and Treatment Effect of DiaPep277®

Study of Intravitreal Aflibercept Injection (IAI; EYLEA®; BAY86-5321) in Patients With Diabetic Macular Edema

An Observational Study of OZURDEX® in Diabetic Macular Edema (DME)

Randomized Trial of Fulvestrant With or Without Dasatinib in Men and Postmenopausal Women Who Have Hormone Receptor-positive Advanced Breast Cancer Previously Treated With an Aromatase Inhibitor

Observe the Effectiveness and Safety of Ranibizumab in Real Life Setting

A Study to Identify and Characterize LAL-D Patients in High-risk Populations

RSV F Dose-Ranging Study in Women

Phase III Study of Florbetaben (BAY94-9172) PET Imaging for Detection/Exclusion of Cerebral β-amyloid Compared to Histopathology

Efficacy an Safety of Volinanserin on Sleep Maintenance Insomnia With a Sub-study on Stable Type II Diabetes Mellitus

An Eight-week Study of Saredutant and Escitalopram as Combination Treatment for Major Depressive Disorder

A Multicentre, Randomized Phase III Study of Rituximab as Maintenance Treatment Versus Observation in Patients With Aggressive B-cell Lymphoma: NHL-13