Clinical Trials in Ohio

Showing 8721-8740 of 20,938 trials

Low-Dose Atropine for Treatment of Myopia

NCT03334253

Study Objectives The objectives for this randomized trial are: 1. To determine the efficacy of daily low-dose atropine (0.01%) for slowing myopia progression over a two-year treatment period in children aged 5 to less than 13 years (Primary Outcome On-Treatment). 2. To determine the efficacy of atropine treatment on myopia progression 6 months following cessation of low-dose atropine treatment (Secondary Outcome Off-Treatment). Synopsis of Study Design The current study is designed as an efficacy study, making effort to maximize adherence to treatment group assignments. After a run-in phase during which all participants are treated with daily artificial tear eyedrops for 2-4 weeks (and glasses are updated if required) to assess their ability to adhere to daily eye drops, participants are randomly assigned to daily atropine or placebo for 24 months, followed by 6 months off treatment.

Myopia

Jaeb Center for Health Research200 participantsStarted Jun 2018

Birmingham, Alabama, United States • Atlanta, Georgia, United States • Boise, Idaho, United States +10 more locations

Active Not Recruiting32 miles

Diagnostic Study of Patients With Acute Lymphoblastic Leukemia or Acute Promyelocytic Leukemia

NCT00003861

This research trial studies molecular genetic features in blood and tissue samples from patients with newly diagnosed acute lymphoblastic leukemia or acute promyelocytic leukemia. Studying samples of blood and tissue from patients with acute lymphoblastic leukemia or acute promyelocytic leukemia in the laboratory may help doctors identify and learn more about biomarkers related to cancer.

LeukemiaAcute Lymphoblastic LeukemiaAcute Promyelocytic Leukemia

Alliance for Clinical Trials in Oncology840 participantsStarted Apr 1999

San Diego, California, United States • San Francisco, California, United States • Lewes, Delaware, United States +48 more locations

Low-Dose Atropine for Treatment of Myopia

Diagnostic Study of Patients With Acute Lymphoblastic Leukemia or Acute Promyelocytic Leukemia

Find Trials by Condition in Ohio

Patiromer Utility as an Adjunct Treatment in Patients Needing Urgent Hyperkalemia Management

Studying Tissue and Blood Samples From Patients With Acute Myeloid Leukemia

Study of Heart Failure Hospitalizations After Aquapheresis Therapy Compared to Intravenous (IV) Diuretic Treatment

Clinical Validation of An Optimized Multi-Target Stool DNA (Mt-sDNA 2.0) Test, for Colorectal Cancer Screening "BLUE-C"

Safety and Efficacy of Nyxol (0.75% Phentolamine Ophthalmic Solution) to Reverse Pharmacologically-Induced Mydriasis (MIRA-3)

Study to Assess the Efficacy and Safety of Rilonacept Treatment in Participants With Recurrent Pericarditis

Pharmacokinetics of Understudied Drugs Administered to Children Per Standard of Care

Intermittent Hypoxia and Caffeine in Infants Born Preterm

DE-117 Spectrum 5 Study

Efficacy and Safety Study of the Use of Benralizumab for Patients With Moderate to Severe Atopic Dermatitis

KD025 in Subjects With Diffuse Cutaneous Systemic Sclerosis

Technology Enabled And Molecular Monitoring of the Allograft and Transplant rEcipient

Assessment of the Safety and Efficacy Study of RGN-259 Ophthalmic Solutions for Neurotrophic Keratopathy : SEER-1

Safety and Efficacy of Pilocarpine Ophthalmic Topical Cream for the Treatment of Presbyopia

Elvucitabine/Efavirenz/Tenofovir Versus Lamivudine/Efavirenz/Tenofovir in Human Immunodeficiency Virus (HIV)-1 Infected, Treatment-naive Participants

Evidence-based Stimulation Trial With Human rFSH in Europe and Rest of World 2

Investigation to Minimize Prolapse Recurrence of the Vagina Using Estrogen

Study of Emerfetamab (AMG 673) in Adults With Relapsed/Refractory Acute Myeloid Leukemia (AML)