Clinical Trials in Ohio

Showing 8141-8160 of 20,938 trials

Epicardial Delivery of XC001 Gene Therapy for Refractory Angina Coronary Treatment (The EXACT Trial)

NCT04125732

The primary purpose of this trial is to determine the safety of XC001 (AdVEGFXC1) in patients who suffer from angina caused by coronary artery disease and have no other treatment options. Subjects in this study will receive one of four intramyocardial doses of XC001 that expresses human vascular endothelial growth factor (VEGF) which induces therapeutic angiogenesis (revascularization).

Coronary Artery DiseaseIschemiaAngina Refractory+2 more

XyloCor Therapeutics, Inc.41 participantsStarted Jan 2020

Stanford, California, United States • Washington D.C., District of Columbia, United States • Daytona Beach, Florida, United States +13 more locations

COMPLETED32 miles

Precision Crohn's Disease Management Utilizing Predictive Protein Panels (ENvISION)

NCT04131504

Crohn's disease and ulcerative colitis affect about 1.6 to 3 million people in the United States with many of those being young children and adolescents. Physicians need better ways to inform decisions on therapy selection and recognize ongoing intestinal injury while on treatment. The main reason for this research study is to see if a blood test or stool test, which measures specific proteins, taken just before starting a new treatment for Crohn's disease can predict a patient's ability to achieve complete intestinal healing. The investigators also want to see if the intensity of gut inflammation can be detected by measuring a separate set of proteins in the blood.

Crohn's DiseaseIBD

Children's Hospital Medical Center, Cincinnati239 participantsStarted Oct 2019

Hartford, Connecticut, United States • Cincinnati, Ohio, United States • Columbus, Ohio, United States +1 more locations

Epicardial Delivery of XC001 Gene Therapy for Refractory Angina Coronary Treatment (The EXACT Trial)

Precision Crohn's Disease Management Utilizing Predictive Protein Panels (ENvISION)

Find Trials by Condition in Ohio

PRT1419 as Monotherapy or in Combination With Azacitidine or Venetoclax in R/R Myeloid or B-cell Malignancies

The Acute Burn ResUscitation Multicenter Prospective Trial

Flotetuzumab in Primary Induction Failure (PIF) or Early Relapse (ER) Acute Myeloid Leukemia (AML)

Study to Assess the Efficacy and Safety of MEDI3506 in Adults With Uncontrolled Moderate-to-severe Asthma

Adavosertib and Local Radiation Therapy in Treating Children With Newly Diagnosed Diffuse Intrinsic Pontine Gliomas

Study of FX006 for the Treatment of Pain in Patients With Osteoarthritis of the Knee

BIO 300 Non-Small Cell Lung Cancer Study

Optimizing Video Communication Assessment for Teaching Error Disclosure Skills

Evaluation of Dupilumab in Patients With Atopic Keratoconjunctivitis (AKC)

STAT: Standard Therapy Plus Active Therapy

A Study of Melphalan Flufenamide (Melflufen)-Dex or Pomalidomide-dex for RRMM Patients Refractory to Lenalidomide

Study to Evaluate the Iovera° Device for Temporary Relief From Knee Pain

Robotic Mechanical Coring for the Treatment of Moderate to Severe Facial Wrinkles

A Phase 1/2, First-in-Human, Open Label, Dose Escalation Study Of A CSP Targeting Functional Antibody in Solid Tumors

Nu-3 Topical Gel for Treatment of Diabetic Foot Ulcer

Study of SNX281 in Subjects With Advanced Solid Tumors and Lymphoma

Study to Evaluate a Procedure for Intra-articular Injection of FX006 in Patients With Osteoarthritis of the Hip

Study on Efficacy and Safety of LNP023 in C3 Glomerulopathy Patients Transplanted and Not Transplanted