Clinical Trials in Ohio

Showing 7801-7820 of 20,938 trials

Biofilm Modified Macrophage Phenotype and Function in Diabetic Wound Healing

NCT03271580

The purpose of this study is to learn more about biofilm and to see how it affects diabetic wounds. A biofilm can occur if a chronic infection causes bacteria to grow in a slime enclosed group. This grouping of bacteria is called a biofilm.

WoundBacterial InfectionsDiabetes Mellitus+1 more

Indiana University31 participantsStarted Feb 2020

Indianapolis, Indiana, United States • Columbus, Ohio, United States • Columbus, Ohio, United States +2 more locations

COMPLETED32 miles

miR-200b & miR-21 in Diabetic Wounds

NCT02581098

This study aims to determine if elevated wound-edge endothelial miR-200b is a barrier to wound healing in diabetic patients and also to determine if ex vivo supplementation of miR-21 mimic and recombinant MFG-E8 resolve inflammation in wound macrophages isolated from NPWT sponges from diabetic wounds. This study will enroll 124 (60 in the miR-200b arm and 64 in the miR21 arm) Diabetic Wound patients who have wound tissue oxygenation adequate to support wound healing and will be in the study for 14 weeks that includes 4 study visits.

Diabetes MellitusFoot UlcerUlcer+3 more

Indiana University98 participantsStarted Aug 2015

Indianapolis, Indiana, United States • Columbus, Ohio, United States • Columbus, Ohio, United States +1 more locations

Biofilm Modified Macrophage Phenotype and Function in Diabetic Wound Healing

miR-200b & miR-21 in Diabetic Wounds

Find Trials by Condition in Ohio

Treatment of Impulsive Aggression (IA) in Adolescent With ADHD in Conjunction With Standard ADHD Treatment

Post Market Study of Parietene™ DS Composite Mesh in Ventral Hernia Repair

Recent-Onset Type 1 Diabetes Trial Evaluating Efficacy and Safety of Teplizumab

Long Term Study of Istradefylline in Subjects With Moderate to Severe Parkinson's Disease

The TESLA Trial: Thrombectomy for Emergent Salvage of Large Anterior Circulation Ischemic Stroke

The Effect of Intrawound Vancomycin Powder in Spine Surgery

Mogamulizumab Q4week Dosing in Participants With R/R CTCL

A Study of Intraperitoneally Administered AVB-001 in Patients With Serous Adenocarcinoma of the Ovary

Safety, Tolerability, and Efficacy Study in Subjects With Advanced or Metastatic Breast Cancer

A Study to Investigate the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics and Efficacy of Risdiplam (RO7034067) in Type 2 and 3 Spinal Muscular Atrophy (SMA) Participants

Efficacy and Safety of S95011 in Primary Sjögren's Syndrome Patients

PH 1 Biomarker Study of Nivolumab and Ipilimumab and Nivolumab in Combination With Ipilimumab in Advanced Melanoma

Efficacy and Safety of Circadin® in the Treatment of Sleep Disturbances in Children With Neurodevelopment Disabilities

Study of Mogamulizumab + MEDI4736 (Durvalumab) and Mogamulizumab + Tremelimumab in Subjects w/ Advanced Solid Tumors

Safety Study to Evaluate Monoclonal Antibody KW-0761 in Subjects With Peripheral T-cell Lymphoma

Expanded Access Protocol: Repeated Administration of Nurown® (Autologous MSC-NTF Cells) for the Treatment of ALS

KHK2455 Alone and in Combination With Mogamulizumab in Subjects With Locally Advanced or Metastatic Solid Tumors

A Study Of PF-04449913 In Select Hematologic Malignancies