Clinical Trials in Minneapolis

Showing 5541-5560 of 14,456 trials

Ketamine Treatment for PTSD and MDD in TBI

NCT06228391

The goal of this clinical trial is to examine the use of sedative ketamine to treat depression and post-traumatic stress disorder (PTSD) in Veterans with mild to moderate traumatic brain injury (TBI). The main questions it aims to answer are: * Efficacy of ketamine to reduce symptoms of depression and/or PTSD * Safety of ketamine to treat depression and/or PTSD in TBI Participants will be randomly assigned to receive either ketamine or midazolam (active placebo) twice a week for 3 weeks. During participation, subjects will be interviewed, have lab tests, and complete rating scales, and questionnaires.

PTSD, Post Traumatic Stress DisorderMajor Depressive DisorderTraumatic Brain Injury

Minneapolis Veterans Affairs Medical Center40 participantsStarted Mar 2024

Minneapolis, Minnesota, United States

TERMINATED< 1 mile

Accelerated Contrast-Enhanced High Resolution Whole Heart Cardiac MRI

NCT02550366

Coronary artery disease (CAD) is the leading cause of death in the United States. Cardiac MRI is a non-invasive non-ionizing technique for a comprehensive cardiac exam, which can be used in the diagnosis of CAD. In this work, the investigators will develop and validate techniques for accelerated cardiac MRI, offering better volumetric coverage of the heart, improved contrast, and superior spatial and temporal resolutions.

Cardiac Disease

University of Minnesota44 participantsStarted Jan 2016

Minneapolis, Minnesota, United States

COMPLETEDPhase 18.7 miles

Renal Impairment Study of PF-06700841

NCT04260464

The purpose of this study is to characterize the effect of kidney impairment on the blood concentrations of PF-06700841 and its major metabolite. Findings from this study will be used to develop dosing recommendations so that the dose and/or dosing interval may be adjusted appropriately in the presence of kidney disease.

Healthy VolunteerRenal Impairment

Pfizer30 participantsStarted Jul 2020

Miami, Florida, United States • Miami, Florida, United States • Saint Paul, Minnesota, United States

Ketamine Treatment for PTSD and MDD in TBI

Accelerated Contrast-Enhanced High Resolution Whole Heart Cardiac MRI

Renal Impairment Study of PF-06700841

Find Trials by Condition in Minneapolis

Study to Assess the Efficacy and Safety of MEDI3506 in Adults With Uncontrolled Moderate-to-severe Asthma

Evaluation of Dupilumab in Patients With Atopic Keratoconjunctivitis (AKC)

Study to Evaluate the Iovera° Device for Temporary Relief From Knee Pain

Flotetuzumab in Primary Induction Failure (PIF) or Early Relapse (ER) Acute Myeloid Leukemia (AML)

Study to Evaluate the Efficacy and Safety of FX006 in Patients With Hip Osteoarthritis

A Study of CART-TnMUC1 in Patients With TnMUC1-Positive Advanced Cancers

Study to Evaluate the Effect of FX006 on Synovial Inflammation in Patients With OA of the Knee

The Metformin Active Surveillance Trial (MAST) Study

Early Diagnosis of Mortality Using Admission CT Perfusion in Severe Traumatic Brain Injury Patients (ACT-TBI Study)

Study of FX006 vs Normal Saline in Patients With Osteoarthritis of the Knee

Study of FX006 for the Treatment of Pain in Patients With Osteoarthritis of the Knee

A Study to Evaluate the Safety and Tolerability of Long-term Administration of Gantenerumab in Participants With Alzheimer's Disease (AD)

V160 2-Dose and 3-Dose Regimens in Healthy Cytomegalovirus (CMV) Seronegative Females (V160-002)

A Study of Melphalan Flufenamide (Melflufen)-Dex or Pomalidomide-dex for RRMM Patients Refractory to Lenalidomide

EPI-743 for Mitochondrial Respiratory Chain Diseases

WAVe Study - Weight Adjusted Dalteparin for Patients Over 90 kg With Acute Cancer Associated Venous Thromboembolism

RoBotic TCD Ultrasound BubbLe Study Compared to Transthoracic Echocardiography for Detection of Right to Left Shunt