Clinical Trials in Maryland

Showing 10081-10100 of 23,284 trials

Impact of Oxytocin on Obstructive Sleep Apnea Induced Changes in Sleep

NCT03148899

In human volunteers intranasal administration of oxytocin significantly increases parasympathetic and decreases sympathetic cardiac control. OSA is a very prevalent disease with high cardiovascular risk factors, yet this disease remains very poorly treated. This proposal, based on the current literature and new basic science results detailed above on the role of oxytocin in cardiovascular control, will test if oxytocin administration improves adverse cardiovascular events during the recurrent nocturnal apneas in patients with OSA. This project will lay the groundwork and provide preliminary data to obtain NIH funding to test this important hypotheses more thoroughly and in larger clinical trials. This study will explore if intranasal oxytocin has any positive cardiovascular benefits in patients with sleep apnea.

Sleep Apnea, Obstructive

George Washington University32 participantsStarted Jul 2016

Washington D.C., District of Columbia, United States

COMPLETEDPhase 317 miles

A Study of Atezolizumab in Combination With Bevacizumab Versus Sunitinib in Participants With Untreated Advanced Renal Cell Carcinoma (RCC)

NCT02420821

This multi-center, randomized, open-label study will evaluate the efficacy and safety of atezolizumab plus bevacizumab versus sunitinib in participants with inoperable, locally advanced, or metastatic RCC who have not received prior systemic active or experimental therapy, either in the adjuvant or metastatic setting.

Renal Cell Carcinoma

Hoffmann-La Roche915 participantsStarted May 2015

Tucson, Arizona, United States • Orange, California, United States • San Francisco, California, United States +151 more locations

Impact of Oxytocin on Obstructive Sleep Apnea Induced Changes in Sleep

A Study of Atezolizumab in Combination With Bevacizumab Versus Sunitinib in Participants With Untreated Advanced Renal Cell Carcinoma (RCC)

Find Trials by Condition in Maryland

Pembrolizumab, Belantamab and Dexamethasone in Refractory Multiple Myeloma.

Efficacy of EsoGuard Assay on Esophageal Surface Cells Collected With EsoCheck vs EGD for the Diagnosis of BE or EAC

Safety, Tolerability, and Efficacy of Anti-Spike (S) SARS-CoV-2 Monoclonal Antibodies for Hospitalized Adult Patients With COVID-19

Study Tests Whether a Standardized LVR Performed With the Blue Egg Device Improves Cardiopulmonary Exercise Capacity

Exercise Trial in Chronic Kidney Disease

Outcome pRognostication of Acute Brain Injury With the NeuroloGical Pupil indEx

Efficacy and Safety of Norketotifen in Uncomplicated Influenza-like Illness

A Phase 3 Study of NI-071 in Participants With Rheumatoid Arthritis (RADIANCE)

Effectiveness and Safety of BMS-986165 Compared to Placebo and Active Comparator in Participants With Psoriasis

Study to Evaluate the Safety and Preliminary Efficacy of IDCT, a Treatment for Symptomatic Lumbar Intervertebral Disc Degeneration

A Study of Baricitinib (LY3009104) in Participants With Systemic Lupus Erythematosus

Assessing the Efficacy and Safety of Brolucizumab Versus Aflibercept in Patients With Visual Impairment Due to Macular Edema Secondary to Branch Retinal Vein Occlusion

Safety Study of KPT-330 (Selinexor) in Patients With Advanced or Metastatic Solid Tumor Cancer

MAIN STUDY: SWITCH SUB-STUDY: SWITCH-JCV

Neuro RX Gamma - Pivotal Phase

A Study to Assess How Well Certolizumab Pegol Works in Patients With Moderate to Severe Plaque Psoriasis as Part of Routine Clinical Practice

Cholangioscopy in Primary Sclerosing Cholangitis (PSC)

Coronavirus Disease (COvid-)19 REgistry on THROMBOSIS Complications