Study Tests Whether a Standardized LVR Performed With the Blue Egg Device Improves Cardiopulmonary Exercise Capacity

Exclusion Criteria

• •Have had a myocardial infarction within 90 days of consent
• •Be inotrope or intra-aortic balloon pump (IABP) dependent
• •Require, in the judgment of the Principal Investigator, cardiac surgery that cannot be deferred for 6 months, such as subjects with:
• •* left main coronary artery disease
• •* intractable ventricular arrhythmias
• •* Canadian Cardiovascular Society Angina Class III or IV symptoms
• •* aortic stenosis or insufficiency requiring replacement
• •* 3+ or 4+ mitral regurgitation
• •Have any comorbid medical condition that is a contraindication to cardiac surgery (e.g., renal failure, coagulopathy, severe chronic obstructive pulmonary disease \[COPD\], cerebrovascular accident \[CVA\], prior stroke, known malignancy etc.)
• •Have congestive heart failure (CHF) due to a cause other than ischemic cardiomyopathy
• •Have a history of radiation therapy to the chest or mediastinum
• •Have exercise tolerance limited by a condition other than heart failure
• •Be unable to perform cardiopulmonary stress test
• •Have a history of alcohol abuse, drug addiction, or other psychosocial condition that would preclude successful participation or realization of benefit from the trial in the opinion of the Principal Investigator.
• •Be a female of child-bearing age who is pregnant or does not agree to use standard methods of birth control.
• •Carry a diagnosis of an illness other than CHF with life expectancy less than 12 months.
• •Participating in another trial (other than non-therapeutic or interventional observation) within the last 30 days or less than 60 days after completion of a heart failure drug trial.
• •Biventricular pacemaker implantation and/or activation within the past 60 days
• •Percutaneous coronary intervention (PCI) with coronary revascularization within the last 60 days.
• •More than one prior sternotomy