Clinical Trials in Illinois

Showing 7481-7500 of 19,692 trials

Dose-finding Study of SPK-8016 Gene Therapy in Patients With Hemophilia A to Support Evaluation in Individuals With FVIII Inhibitors

NCT03734588

SPK-8016 is in development for the treatment of patients with inhibitors to FVIII. This Phase 1/2, open-label, non-randomized, dose-finding study to evaluate the safety, efficacy, and tolerability of SPK-8016 in adult males with severe hemophilia A and no measurable inhibitor against FVIII.

Adeno-Associated Virus (AAV)Blood Coagulation DisorderBlood Coagulation Disorders, Inherited+14 more

Spark Therapeutics, Inc.4 participantsStarted Jan 2019

Los Angeles, California, United States • Peoria, Illinois, United States • Ann Arbor, Michigan, United States +8 more locations

RECRUITINGNA51 miles

Reducing Opioid Mortality in Illinois

NCT04925427

Reducing Opioid Mortality in Illinois (ROMI) is 5-year research study led by the University of Chicago in partnership with the University of Illinois at Chicago's (UIC) Community Outreach Intervention Projects (COIP), the Illinois Criminal Justice Information Authority (ICJIA) and the American Institutes for Research (AIR). ROMI aims to understand and test strategies for linking individuals with a history of opioid use disorder who are released from Illinois jails and prisons to substance use treatment. ROMI is one of twelve grants awarded by the National Institutes of Health (NIH) as part of the Justice Community Opioid Innovation Network (JCOIN) to support research on quality addiction treatment for opioid use disorder in criminal justice settings nationwide.

Opioid UseOpioid-use Disorder

University of Chicago1,500 participantsStarted Aug 2021

Chicago, Illinois, United States • Murphysboro, Illinois, United States • Ottawa, Illinois, United States +2 more locations

Dose-finding Study of SPK-8016 Gene Therapy in Patients With Hemophilia A to Support Evaluation in Individuals With FVIII Inhibitors

Reducing Opioid Mortality in Illinois

Find Trials by Condition in Illinois

Prevalence of PD-L1 Expression in Patients With Advanced Urothelial Carcinoma

Pilot Immunotherapy Study With Letetresgene Autoleucel (Lete-cel, GSK3377794)T-cells in New York Esophageal Squamous Cell Carcinoma-1 (NY-ESO-1)/ LAGE-1a-positive Advanced Non-small Cell Lung Cancer (NSCLC) Either Alone or in Combination With Pembrolizumab

Afimoxifene in Reducing the Risk of Breast Cancer in Women With Mammographically Dense Breast

Efficacy & Safety Evaluation of Enobosarm in Combo With Abemaciclib in Treatment of ER+HER2- Metastatic Breast Cancer

Development and Testing of a Pediatric Cervical Spine Injury Risk Assessment Tool

Study to Evaluate the Efficacy and Safety of Oral Difelikefalin as Adjunct Therapy to a Topical Corticosteroid for Moderate to Severe Pruritus in Subjects With Atopic Dermatitis

Diabetes Study of Linagliptin and Empagliflozin in Children and Adolescents (DINAMO)TM

Safety and Efficacy Comparison of Docetaxel and Ixabepilone in Non Metastatic Poor Prognosis Breast Cancer

Electrically Evoked Compound Action Potentials Human Observation Medtronic Algorithm Comparison Study

A Comparative Study Between PF-06410293 and Humira® in Combination With Methotrexate in Participants With Active Rheumatoid Arthritis

Gene Therapy With hLB-001 in Pediatric Patients With Severe Methylmalonic Acidemia

Observational Registry to Assess the Durability of Effect of CXL in Patients With Corneal Ectasia After Refractive Surgery

Pilot Prospective Study: Long-term Health of Living Kidney Donors

Evaluating Two Multifocal Daily Disposable Contact Lenses

This Study is to Evaluate Safe and Effective Treatment Dose of OBI-888 in Patients With Locally Advanced or Metastatic Solid Tumors.

Nivolumab Ipilimumab in Patients With hyperMutated Cancers Detected in Blood (NIMBLe)

COMbination of Bipolar Androgen Therapy and Nivolumab

The RECSUR-study: Resection Versus Best Oncological Treatment for Recurrent Glioblastoma (ENCRAM 2302)