Pilot Prospective Study: Long-term Health of Living Kidney Donors

Exclusion Criteria

• •1. A medical condition (such as cardiovascular disease, pulmonary disease, active cancer) or psychological condition (such as major affective disorder, personality disorder, a history of chemical dependence) which the local transplant centre deems unfit for donation. Blood group and immunological incompatibility (such as positive cross-match, poor HLA matches) are not reasons for exclusion
• •2. Evidence of a financial incentive for donation
• •3. A contraindication to general anaesthesia or surgery
• •4. A past medical history of hypertension
• •5. Use of antihypertensive class medications for any reason.(ACE-Is, ARBs, diuretics, beta-blockers, calcium channel blockers)
• •6. A past history of permanent proteinuria
• •7. The eligible non-donor is planning to donate their kidney within the next year
• •8. Unable to give informed consent
• •9. Unwilling to participate in the follow-up assessments at one, two, three, four and five years, or unwilling or unable to conduct home blood pressure or laboratory measurements
• •10. The living donor or eligible non-donor is currently pregnant
• •11. Despite being planned the donor nephrectomy does not take place
• •12. Enrolled in another clinical study which interferes with the conduct or outcomes of this study