Clinical Trials in Illinois

Showing 5961-5980 of 19,692 trials

Evaluation of Lasofoxifene Combined With Abemaciclib in Advanced or Metastatic ER+/HER2- Breast Cancer With an ESR1 Mutation

NCT04432454

This is an open-label, multicenter, single-arm safety study evaluating the safety and tolerability of the lasofoxifene and abemaciclib combination for the treatment of pre- and postmenopausal women with locally advanced or metastatic ER+/HER2- breast cancer who have disease progression on first and/or 2nd lines of hormonal treatment for metastatic disease and have an ESR1 mutation.

Metastatic Breast Cancer

Sermonix Pharmaceuticals Inc.29 participantsStarted Sep 2020

Birmingham, Alabama, United States • Yuma, Arizona, United States • Fountain Valley, California, United States +13 more locations

RECRUITINGPhase 1/2125 miles

Evaluate the Safety, Tolerability, Pharmacodynamics and Efficacy of CNP-106 in Subjects With Myasthenia Gravis

NCT06106672

Phase 1b/2a First-in-Human (FIH) clinical trial to assess the safety, tolerability, pharmacodynamics (PD), and efficacy of multiple ascending doses of CNP-106.

Myasthenia GravisGeneralized MyastheniaAChR Myasthenia Gravis+1 more

COUR Pharmaceutical Development Company, Inc.54 participantsStarted May 2024

Phoenix, Arizona, United States • Phoenix, Arizona, United States • Brea, California, United States +14 more locations

Evaluation of Lasofoxifene Combined With Abemaciclib in Advanced or Metastatic ER+/HER2- Breast Cancer With an ESR1 Mutation

Evaluate the Safety, Tolerability, Pharmacodynamics and Efficacy of CNP-106 in Subjects With Myasthenia Gravis

Find Trials by Condition in Illinois

Evaluation of the Phased Radio Frequency Ablation System

Pulsed Field Ablation to Irreversibly Electroporate Tissue and Treat AF

ATHN 7: Hemophilia Natural History Study

A Pivotal Study of Safety and Effectiveness of NanoKnife IRE for Stage 3 Pancreatic Cancer

A Study of AK117 in Combination With Azacitidine in Patients With Myelodysplastic Syndromes

A Study of ERAS-007 in Patients With Advanced Gastrointestinal Malignancies

Selumetinib and Cyclosporine in Treating Patients With Advanced Solid Tumors or Advanced or Metastatic Colorectal Cancer

LYT-200 Alone and in Combination With Chemotherapy or Tislelizumab in Patients With Locally Advanced or Metastatic Solid Tumors

At-Risk for Type 1 Diabetes Extension Study (TN-10 Extension)

Rising Tide - Amniotic Tissue(s) Treatments for Chronic Diabetic Foot Ulcers

A Study of Participants with Β-Thalassemia Treated with Betibeglogene Autotemcel

TK216 in Patients With Relapsed or Refractory Ewing Sarcoma

Non-comparative Study of IFX-1 Alone or IFX-1+Pembrolizumab in Patients With Locally Advanced or Metastatic cSCC.

Artoss Prospective Spine Registry Outcomes

Psychological Response and Readiness Associated With OCD of the Knee

A Food Additive Removal Diet for Pediatric Eosinophilic Esophagitis

Study of ExoFlo for the Treatment of Medically Refractory Crohn's Disease

An International Multicenter Study on Transcatheter Device Closure of Perimembranous Ventricular Septal Defects