Clinical Trials in Illinois

Showing 5941-5960 of 19,692 trials

Evaluation of Lasofoxifene Combined With Abemaciclib in Advanced or Metastatic ER+/HER2- Breast Cancer With an ESR1 Mutation

NCT04432454

This is an open-label, multicenter, single-arm safety study evaluating the safety and tolerability of the lasofoxifene and abemaciclib combination for the treatment of pre- and postmenopausal women with locally advanced or metastatic ER+/HER2- breast cancer who have disease progression on first and/or 2nd lines of hormonal treatment for metastatic disease and have an ESR1 mutation.

Metastatic Breast Cancer

Sermonix Pharmaceuticals Inc.29 participantsStarted Sep 2020

Birmingham, Alabama, United States • Yuma, Arizona, United States • Fountain Valley, California, United States +13 more locations

Active Not RecruitingPhase 251 miles

Radiation Therapy With or Without Chemotherapy in Treating Patients With High-Risk Malignant Salivary Gland Tumors That Have Been Removed By Surgery

NCT01220583

RATIONALE: Radiation therapy uses high-energy x-rays to kill tumor cells. Drugs used in chemotherapy, such as cisplatin, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing. It is not yet known whether radiation therapy is more effective when given together with chemotherapy or alone after surgery in treating salivary gland tumors. PURPOSE: This randomized phase II/III trial is studying radiation therapy with or without chemotherapy to see how well it works in treating patients with high-risk malignant salivary gland tumors that have been removed by surgery.

Head and Neck Cancer

Radiation Therapy Oncology Group252 participantsStarted Jan 2011

Birmingham, Alabama, United States • Birmingham, Alabama, United States • Gilbert, Arizona, United States +265 more locations

Evaluation of Lasofoxifene Combined With Abemaciclib in Advanced or Metastatic ER+/HER2- Breast Cancer With an ESR1 Mutation

Radiation Therapy With or Without Chemotherapy in Treating Patients With High-Risk Malignant Salivary Gland Tumors That Have Been Removed By Surgery

Find Trials by Condition in Illinois

Study Assessing the Efficacy and Safety of Alpelisib Plus Fulvestrant in Men and Postmenopausal Women With Advanced Breast Cancer Which Progressed on or After Aromatase Inhibitor Treatment.

Intracardiac CrYoablation for AtrioVentricular Nodal Reentrant Tachycardia

Mapping the Genotype, Phenotype, and Natural History of Phelan-McDermid Syndrome

A Study Evaluating Safety and Tolerability, and Pharmacokinetics of Navitoclax Monotherapy and in Combination With Ruxolitinib in Participants With Myeloproliferative Neoplasm

IO-202 as Monotherapy and IO-202 Plus Azacitidine ± Venetoclax in Patients in AML and CMML

Pulsed Field Ablation to Irreversibly Electroporate Tissue and Treat AF

Evaluate the Safety, Tolerability, Pharmacodynamics and Efficacy of CNP-106 in Subjects With Myasthenia Gravis

Trametinib in Treating Patients With Advanced Cancer With or Without Hepatic Dysfunction

Myeloma-Developing Regimens Using Genomics (MyDRUG)

INFINITY™Total Ankle Replacement Follow-up

Tamoxifen in Women With Breast Cancer and in Women at High-Risk of Breast Cancer Who Are Receiving Venlafaxine, Citalopram, Escitalopram, Gabapentin, or Sertraline

Alcoholic Hepatitis Network Observational Study

COVID-19 Vaccine Response in Sickle Cell Disease

TAC T-cells for the Treatment of Claudin 18.2 Positive Solid Tumors (TACTIC-3)

A Study of Lumasiran in Infants and Young Children With Primary Hyperoxaluria Type 1

Evaluation of Brimonidine Tartrate/Ketotifen Fumarate Combination for the Treatment of Allergic Conjunctivitis

Study of the Efficacy of Lurasidone in Cognitive Functioning in Bipolar Patients

MCT for the Harvard/UCSF ROBIN Center