Clinical Trials in Illinois

Showing 5421-5440 of 19,692 trials

A Study of PF-07260437 in Advanced or Metastatic Solid Tumors

NCT05067972

A study to evaluate the safety, tolerability, pharmacokinetics (PK), pharmacodynamics (PD), and antitumor activity of PF-07260437, a B7-H4 x CD3 bispecific mAb, in participants aged ≥18 years of age with advanced or metastatic breast cancer, ovarian cancer or endometrial cancer. Adult participants with other advanced or metastatic high B7-H4 expressing tumors may be considered after discussion with and approval from sponsor.

Ovarian NeoplasmsEndometrial NeoplasmsBreast Neoplasms

Pfizer30 participantsStarted Oct 2021

Duarte, California, United States • Tampa, Florida, United States • Tampa, Florida, United States +12 more locations

TERMINATEDPhase 1/2121 miles

A Study to Evaluate Safety, Tolerability, Dosimetry, and Preliminary Efficacy of the HER2 Directed Radioligand CAM-H2 in Patients With Advanced/Metastatic HER2-Positive Breast, Gastric, and Gastro-Esophageal Junction (GEJ) Cancer

NCT04467515

This is a Phase 1/2 multi-center, open label, dose escalation and dose expansion study to evaluate safety, tolerability, dosimetry, pharmacodynamics (PD), and efficacy of the targeted radionuclide therapeutic CAM-H2 in patients with progressive, advanced/metastatic HER2-positive breast, gastric, and GEJ cancer with disease progression following anti-HER2 standard of care treatment.

Advanced/Metastatic HER2-positive Breast, Gastric, Gastroesophageal Junction Cancer With Disease Progression Following Anti-HER2 Standard of Care Treatment

Precirix13 participantsStarted Sep 2021

Duarte, California, United States • Stanford, California, United States • Washington D.C., District of Columbia, United States +9 more locations

A Study of PF-07260437 in Advanced or Metastatic Solid Tumors

A Study to Evaluate Safety, Tolerability, Dosimetry, and Preliminary Efficacy of the HER2 Directed Radioligand CAM-H2 in Patients With Advanced/Metastatic HER2-Positive Breast, Gastric, and Gastro-Esophageal Junction (GEJ) Cancer

Find Trials by Condition in Illinois

A Study to Determine the Safety and Efficacy of the RSV F Vaccine to Protect Infants Via Maternal Immunization

KIR Favorable Mismatched Haplo Transplant and KIR Polymorphism in ALL/AML/MDS Allo-HCT Children

CMV CTLs in Neonates With CMV Infection

T1D Pregnancy & Me

Afrezza® INHALE-1 Study in Pediatrics

Examining the Effectiveness of Cognitive Training

Safe and Timely Antithrombotic Removal - Direct Oral Anticoagulants Apixaban & Rivaroxaban (STAR-D)

Log2Lose: Incenting Weight Loss and Dietary Self-monitoring in Real-time to Improve Weight Management Among Adults With Obesity

Changes in Biomarker of Exposure in Adults Who Smoke Cigarettes Switching From Cigarettes to Heated Tobacco Products

Safety, Tolerability, PK/PD & Preliminary Efficacy of SKL27969 in Advanced Solid Tumors Patients

Study of BOTOX Injections to Assess Change in Disease Activity and Adverse Events in Adult Female Participants With Interstitial Cystitis/Bladder Pain Syndrome (IC/BPS)

A Phase II, Cross-over Clinical Trial Evaluating the Efficacy and Safety of KVD900 (Sebetralstat) in the On-demand Treatment of Angioedema Attacks in Adult Subjects With Hereditary Angioedema Type I or II

The OBSERVE Protocol

HOPE-B: Trial of AMT-061 in Severe or Moderately Severe Hemophilia B Patients

Trial of Dichloroacetate in Pyruvate Dehydrogenase Complex Deficiency:

Imaging to Improve Brain Stimulation

Repurposing Nucleoside Reverse Transcriptase Inhibitors for Treatment of AD

A Study of Copanlisib Combined With Rucaparib in Patients With Metastatic Castration-resistant Prostate Cancer