Clinical Trials in Georgia

Showing 13221-13240 of 19,050 trials

Evaluation of Environmental Emissions From Electronic Cigarettes and Tobacco-Burning Cigarettes

NCT02185898

This study will assess environmental emissions of selected compounds in a test chamber after cigarette smoking or e-cigarette vaping.

Smoking

R.J. Reynolds Vapor Company71 participantsStarted May 2014

Stockbridge, Georgia, United States

COMPLETEDPhase 265 miles

Ofatumumab Subcutaneous Administration in Subjects With Relapsing-Remitting Multiple Sclerosis

NCT01457924

Ofatumumab is a novel Immunoglobulin 1ĸ ( IgG1ĸ) lytic monoclonal antibody (mAb) that specifically binds to the human Cluster of Differentiation 20 (CD20) antigen of which expression is restricted to B lymphocytes from the pre-B cell stage to the plasmacytoid immunoblast stage only. A recent trial with an anti-CD20 mAb (rituximab) demonstrated that targeting B-cells reduces the number of gadolinium-enhancing (GdE) T1 lesions and the relapse rate in relapsing-remitting multiple sclerosis (RRMS). Ofatumumab has been shown to be both well tolerated and efficacious in several indications, including a small, placebo-controlled trial in RRMS using an intravenous (IV) formulation. This double-blind, placebo-controlled, parallel-group study will investigate the safety and efficacy of a subcutaneous formulation of ofatumumab in the treatment of subjects with RRMS. The primary objective of the study is to investigate the efficacy as assessed by magnetic resonance imaging. Other objectives will include evaluation of tolerability/safety, dose-response relationship, pharmacokinetics, pharmacodynamics, exposure-response, as well as other clinical endpoints.

Multiple Sclerosis

GlaxoSmithKline232 participantsStarted Nov 2011

Cullman, Alabama, United States • Fullerton, California, United States • Fairfield, Connecticut, United States +58 more locations

Evaluation of Environmental Emissions From Electronic Cigarettes and Tobacco-Burning Cigarettes

Ofatumumab Subcutaneous Administration in Subjects With Relapsing-Remitting Multiple Sclerosis

Find Trials by Condition in Georgia

Bilateral Cochlear Implantation in Children With the MED-EL Cochlear Implant

Comparative Study of NXL104/Ceftazidime Versus Comparator in Adults With Complicated Urinary Tract Infections

A Study of PF-06438179 (Infliximab-Pfizer) and Infliximab in Combination With Methotrexate in Subjects With Active Rheumatoid Arthritis (REFLECTIONS B537-02).

Study to Evaluate the Efficacy and Safety of Saxagliptin Co-administered With Dapagliflozin in Combination With Metformin Compared to Sitagliptin in Combination With Metformin in Adult Patients With Type 2 Diabetes Who Have Inadequate Glycemic Control on Metformin Therapy Alone

A Phase 2 Study of Vapendavir in Asthmatic Adults With Symptomatic Human Rhinovirus Infection

ATLAS: Ambulatory Treatments for Leakage Associated With Stress

Outcomes Following Vaginal Prolapse Repair and Mid Urethral Sling Trial

Dose Escalation of OXi4503 as Single Agent and Combination With Cytarabine w/Subsequent Ph 2 Cohorts for AML and MDS

A Study for Safety and Effectiveness of IMC-A12 by Itself or Combined With Antiestrogens to Treat Breast Cancer

Safety and Efficacy of Combination Listeria/GVAX Pancreas Vaccine in the Pancreatic Cancer Setting

Thrombolysis in Pediatric Stroke (TIPS)

Scleroderma Treatment With Celution Processed Adipose Derived Regenerative Cells (STAR)

Study Comparing Treatment Effectiveness of Guideline Indicated APT for ACS in Patients With CKD

OLIF25™ /OLIF51™ Study

Regional and Seasonal Variations in the Incidence and Causative Organisms for Post-traumatic Wound Infections and Osteomyelitis After Open Fractures

Imatinib Mesylate in Treating Patients With HIV-Related Kaposi's Sarcoma

Alisertib (MLN8237) in Participants With Ovarian, Fallopian Tube or Peritoneal Cancer Preceded by Phase 1 Study of MLN8237 Plus Paclitaxel Treatment of Ovary or Breast Cancer

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