Clinical Trials in Detroit

Showing 15761-15780 of 19,719 trials

Randomized Trial of Suicide Gene Therapy and Prostate Cancer

NCT00583492

This is a randomized, controlled trial that will test the hypothesis that replication-competent adenovirus-mediated suicide gene therapy in combination with 80 Gy intensity modulated radiotherapy (IRMT)will improve freedom from failure (FFF) relative to 80 Gy IMRT alone in patients with newly-diagnosed prostate cancer with an intermediate-risk profile.

Prostate Cancer

Henry Ford Health System44 participantsStarted Dec 2007

Baltimore, Maryland, United States • Detroit, Michigan, United States

COMPLETEDPhase 2/3< 1 mile

Atacicept Phase 2/3 in Generalized Systemic Lupus Erythematosus (APRIL-SLE)

NCT00624338

This study is to evaluate the efficacy and safety of atacicept compared to placebo in preventing new flares in subjects with systemic lupus erythematosus (SLE) and to confirm the optimal dose of atacicept for treatment of subjects with SLE and gain information on the effect of atacicept on markers specific to its mechanism of action (MoA) and their correlation to disease activity/progression. Study medication will be administered through subcutaneous (under the skin) injections, beginning with twice weekly injections for the first 4 weeks, followed by once weekly doses for 48 weeks. Following the last treatment, a safety follow-up period of 24 weeks will be conducted.

Lupus Erythematosus, Systemic

EMD Serono461 participantsStarted Jan 2008

Birmingham, Alabama, United States • Palo Alto, California, United States • San Diego, California, United States +110 more locations

Randomized Trial of Suicide Gene Therapy and Prostate Cancer

Atacicept Phase 2/3 in Generalized Systemic Lupus Erythematosus (APRIL-SLE)

Find Trials by Condition in Detroit

Safety and Efficacy of BKM120 in Patients With Metastatic Non-small Cell Lung Cancer

An Observational Study on Long-Term Persistence of Resistant Mutations And Durability of Sustained Virological Response in Patients With Chronic Hepatitis C Treated With Direct Acting Antiviral (DAA)- Containing Regimens

Ocriplasmin for Treatment for Symptomatic Vitreomacular Adhesion Including Macular Hole

A Study Evaluating INIPARIB in Combination With Chemotherapy to Treat Triple Negative Breast Cancer Brain Metastasis

Evaluation of the Efficacy and Safety of E2007 (Perampanel) Given as Adjunctive Therapy in Subjects With Refractory Partial Seizures

Safety and Efficacy of Eslicarbazepine Acetate Monotherapy in Subjects With Partial Epilepsy Not Well Controlled by Current Antiepileptic Drugs

Safety and Efficacy Study of Ramelteon (TAK-375) Tablets for Sublingual Administration (SL) in Adults With Bipolar 1 Disorder

Open Label Extension of Prior TERMS Study to Treat Relapsing Forms of Multiple Sclerosis

A Long-Term Safety and Efficacy Study of Eszopiclone in Elderly With Primary Chronic Insomnia

Post-Approval Study of MelaFind

Study Investigating the Safety and Efficacy of HP802-247 in the Treatment of Venous Leg Ulcers

Bosutinib For Autosomal Dominant Polycystic Kidney Disease

Efficacy, Safety And Tolerability Study Of RN6G In Subjects With Geographic Atrophy Secondary to Age-related Macular Degeneration

Phase II Trial of Weekly or Every 3-week Ixabepilone for Patients With Metastatic Breast Cancer

A Study To Investigate The Pharmacokinetics, Safety And Tolerability Of An Intravenous And Oral Form Of A Compound In Subjects With Varying Degrees Of Renal Impairment And Normal Renal Function

Lurasidone HCL - A 6-week Phase 3 Study of Patients With Acute Schizophrenia.

Elder Surgery - Functional Recovery Following Beta Blockade

Comparison of AZD6244 in Combination With Dacarbazine Versus (vs) Dacarbazine Alone in BRAF Mutation Positive Melanoma Patients