Clinical Trials in Detroit

Showing 15741-15760 of 19,719 trials

A Study Evaluating the Safety, Tolerability, and Pharmacokinetics of GDC-0973 in Combination With GDC-0068 When Administered in Participants With Locally Advanced or Metastatic Solid Tumors

NCT01562275

This open-label, multicenter, Phase Ib dose-escalation study will evaluate the safety, tolerability and pharmacokinetics of oral dosing of GDC-0973 and GDC-0068 administered in combination in patients with locally advanced or metastatic solid tumors. Cohorts of patients will receive multiple ascending doses of GDC-0973 and GDC-0068. Anticipated time on study treatment is until disease progression or unacceptable toxicity occurs.

Neoplasms

Genentech, Inc.67 participantsStarted Apr 2012

Boston, Massachusetts, United States • Detroit, Michigan, United States • Nashville, Tennessee, United States +2 more locations

TERMINATEDPhase 2/3< 1 mile

The Efficacy and Safety of Atacicept in Combination With Mycophenolate Mofetil Used to Treat Lupus Nephritis

NCT00573157

The purpose of this study is to learn whether atacicept treatment leads to improvement in kidney function in subjects with active lupus nephritis in combination with mycophenolate mofetil (MMF) and corticosteroids. The study was sponsored by Merck Serono International; operational oversight was provided by ZymoGenetics.

Lupus Nephritis

EMD Serono6 participantsStarted Dec 2007

New Orleans, Louisiana, United States • Shreveport, Louisiana, United States • Detroit, Michigan, United States +17 more locations

A Study Evaluating the Safety, Tolerability, and Pharmacokinetics of GDC-0973 in Combination With GDC-0068 When Administered in Participants With Locally Advanced or Metastatic Solid Tumors

The Efficacy and Safety of Atacicept in Combination With Mycophenolate Mofetil Used to Treat Lupus Nephritis

Find Trials by Condition in Detroit

Topotecan in Treating Patients With Recurrent Extensive-Stage Small Cell Lung Cancer

Evaluation of Weekly Idrabiotaparinux Sodium Versus Oral Adjusted-dose Warfarin to Prevent Stroke and Systemic Thromboembolic Events in Patients With Atrial Fibrillation

Randomized Trial of Suicide Gene Therapy and Prostate Cancer

Ragweed-SPIRE Follow-On Study

Study of Acute Peripheral Vascular Effects, Safety and Tolerability in Subjects With Raynaud's Phenomenon Secondary to Systemic Sclerosis

Care Partners: Web-based Support for Caregivers of Veterans Undergoing Chemotherapy

Study Intended to Evaluate the Safety and Effectiveness of a Johnson & Johnson Vision Care Inc, (JJVCI) Contact Lens for Use on an Extended-wear Basis for up to 7 Days (6 Nights).

Retrospective Multicenter Study to Determine 4-Year Clinical Outcomes in Subjects Previously Enrolled in the CTOT-05 Study

Chemotherapy With or Without Strontium-89 in Treating Patients With Prostate Cancer

Study of Intravenous NRX-1074 in Patients With Major Depressive Disorder

Clinical Outcomes and Safety: A Registry Study of Ilaris (Canakinumab) Patients

Long-term, Safety and Tolerability Study of AFQ056 in Adolescent Patients With Fragile X Syndrome (Open-label)

Efficacy and Safety of GLYX-13 in Subjects With Inadequate/Partial Response to Antidepressants

Safety and Efficacy of EVT 101 in Treatment-Resistant Depression

Lurasidone HCL - A 6-week Phase 3 Study of Patients With Acute Schizophrenia.

Clinical Study Assessing Idrabiotaparinux Sodium Injections Once-weekly in Pulmonary Embolism Therapeutic Approach

Bioequipotency Study of Idrabiotaparinux and Idraparinux in Patients With Deep Venous Thrombosis of the Lower Limbs

Bioequivalence Study of IG-001 Versus Nab-paclitaxel in Metastatic or Locally Recurrent Breast Cancer