Clinical Trials in Denver

Showing 8021-8040 of 18,161 trials

(EXPLORER) Study of BLU-285 in Patients With Advanced Systemic Mastocytosis (AdvSM) and Relapsed or Refractory Myeloid Malignancies

NCT02561988

This is a Phase 1, open-label, dose-escalation study designed to evaluate the safety, tolerability, pharmacokinetics (PK), pharmacodynamics (PD) and antineoplastic activity of avapritinib (also known as BLU-285), administered orally (PO), in adult patients with advanced systemic mastocytosis and other relapsed or refractory myeloid malignancies. The study consists of 2 parts:, dose-escalation (Part 1) and expansion (Part 2).

Aggressive Systemic MastocytosisSystemic Mastocytosis-associated Hematologic Non-mast Cell DiseaseMast Cell Leukemia+1 more

Blueprint Medicines Corporation86 participantsStarted Mar 2016

Stanford, California, United States • Denver, Colorado, United States • Atlanta, Georgia, United States +8 more locations

COMPLETED< 1 mile

Streamlining Trauma Research Evaluation With Advanced Measurement

NCT02079714

The STREAM Study is a prospective longitudinal observational outcomes study that will examine the reliability, validity and responsiveness of the PROMIS tools for clinical research following orthopaedic trauma.

Orthopaedic Trauma

Major Extremity Trauma Research Consortium1,065 participantsStarted Jan 2014

Birmingham, Alabama, United States • San Diego, California, United States • San Francisco, California, United States +41 more locations

(EXPLORER) Study of BLU-285 in Patients With Advanced Systemic Mastocytosis (AdvSM) and Relapsed or Refractory Myeloid Malignancies

Streamlining Trauma Research Evaluation With Advanced Measurement

Find Trials by Condition in Denver

A Study to Test if TEV-48574 is Effective in Relieving Asthma

A 24-Week Treatment Study to Compare Standard of Care Versus the eMDPI DS in Participants 13 Years or Older With Asthma

A Randomized, Controlled Trial of Ganaxolone in Adult Uncontrolled Partial-Onset Seizures

A Prospective Clinical Study of Phenylketonuria (PKU)

Evaluation of Performance of the LumiraDx Influenza A/B + RSV Test at POC Testing Sites

Research & Evaluation of LumiraDx SARS-CoV-2 (COVID-19) Point of Care Ab Test

A Safety and Efficacy Study of BBI-4000 in Subjects With Axillary Hyperhidrosis

Evaluation of QDOT MICRO™ Catheter for Pulmonary Vein Isolation in Subjects With Paroxysmal Atrial Fibrillation

Rituximab Plus Venetoclax in Combination With Zandelisib in Subjects With CLL

An Evaluation of the Effect of Low Level Laser Therapy on Diabetic Peripheral Neuropathy Pain

A Study Evaluating Bilastine Ophthalmic Solution 0.6% in the Conjunctival Allergen Challenge (Ora-CAC®) Model.

Assessment of Safety and Efficacy of Nerivio for the Migraine Prevention

Genetic Data Collection in Adult Participants to Identify Genetic Variants of Known Importance in Non-alcoholic Steatohepatitis (NASH)

An Open Label Study of NLS-2 (Mazindol Extended Release) in Subjects With Narcolepsy

Neoadjuvant Carboplatin and Vincristine and Standard Local Ophthalmic Therapy in Treating Patients With Intraocular Retinoblastoma

A Study Assessing the Safety, Efficacy, and Optimum Dosage of K-161 in Subjects With Moderate to Severe Dry Eye Disease

A Study of Atezolizumab (MPDL3280A) Compared With a Platinum Agent (Cisplatin or Carboplatin) + (Pemetrexed or Gemcitabine) in Participants With Stage IV Non-Squamous or Squamous Non-Small Cell Lung Cancer (NSCLC) [IMpower110]

FREEDOM COVID-19 Anticoagulation Strategy