Clinical Trials in Cleveland

Showing 4481-4500 of 19,775 trials

ABL103 in Combination With Pembrolizumab, With or Without Taxane in Advanced or Metastatic Solid Tumors

NCT07158918

This study is to assess the safety and antitumor activity of ABL103 plus pembrolizumab, with or without taxane, in advanced or metastatic solid tumors.

Solid Tumors

ABL Bio, Inc.65 participantsStarted Aug 2025

Cleveland, Ohio, United States • Frankston, Victoria, Australia • Seongnam, South Korea +3 more locations

Active Not RecruitingPhase 1< 1 mile

Ivosidenib + mFOLFIRINOX in Patients With Resectable Pancreatic Adenocarcinoma

NCT05209074

This study is a single-arm, phase I trial, up to 16 participants with resectable PDA. The study will examine the efficacy of the mutant IDH1 inhibitor ivosidenib, in conjunction with standard-of-care mFOLFIRINOX in the neoadjuvant setting.

Pancreatic Ductal AdenocarcinomaResectable Pancreatic Cancer

Case Comprehensive Cancer Center16 participantsStarted Sep 2022

Cleveland, Ohio, United States

Active Not RecruitingPhase 3< 1 mile

A Study to Assess the Effect of Dexpramipexole in Adolescents and Adults With Eosinophilic Asthma

NCT05748600

The purpose of this study is to evaluate dexpramipexole as an add-on oral therapy in participants with inadequately controlled eosinophilic asthma to evaluate improvements in lung function, asthma control, and quality of life. In addition, the study will further evaluate the safety and tolerability of dexpramipexole in participants with eosinophilic asthma.

Eosinophilic AsthmaAsthma; EosinophilicAsthma Attack

Areteia Therapeutics600 participantsStarted Jan 2023

Chandler, Arizona, United States • Peoria, Arizona, United States • Surprise, Arizona, United States +332 more locations

ABL103 in Combination With Pembrolizumab, With or Without Taxane in Advanced or Metastatic Solid Tumors

Ivosidenib + mFOLFIRINOX in Patients With Resectable Pancreatic Adenocarcinoma

A Study to Assess the Effect of Dexpramipexole in Adolescents and Adults With Eosinophilic Asthma

Find Trials by Condition in Cleveland

Collection of Peripheral Blood From Patients With Hematologic Malignancies With Thrombocytopenia

Efficacy, Safety, Tolerability, and Pharmacokinetics of NBI-827104 in Pediatric Subjects With Epileptic Encephalopathy With Continuous Spike-and-Wave During Sleep

The Combined Effect of Intravesical Botox Injections and HoLEP Surgery in Treating Benign Prostatic Hyperplasia and Overactive Bladder

Phase 2b Study of ALTO-100 in MDD

A Study Evaluating the Long-term Safety and Efficacy of VX-121 Combination Therapy

CREST-2 Long-term Observational Extension Study

A Double-blind Study to Evaluate the Safety of Glutamic Acid Decarboxylase Gene Transfer in Parkinson's Participants

A Study of Danicopan in Participants With Geographic Atrophy Secondary to Age-Related Macular Degeneration

Expanded Access Program for Revumenib

Study of a Pneumococcal Conjugate Vaccine When Administered Concomitantly With Routine Pediatric Vaccines in Healthy Toddlers and Infants

Cognitive Behavioural Therapy to Optimize Post-Operative Recovery Trial

Safety Study to Evaluate the Occurrence of EFAD in Pediatric Patients With PNAC Who Require More Than Eight Weeks of Omegaven Treatment

Maximal Use Study of Tapinarof Cream, 1% in Pediatric Subjects With Extensive Atopic Dermatitis

Velocity 2: An Anthrax Vaccine and Antibiotics Clinical Study

The PLATFORM Study: Prospective LongitudinAl Trial of FFRct: Outcome and Resource IMpacts)

A Study of Renal Microvessel Imaging for Chronic Kidney Disease

Skin Reactions Related to Thoracic Implantable Chamber Dressings