Clinical Trials in Chicago

Showing 10381-10400 of 20,493 trials

Sleep Quality, Heart Rate Variability and Anxiety Following Brain Injury

NCT04652895

The investigators predict that decreased heart rate variability and poor sleep quality will be significantly correlated with higher self-reported anxiety following brain injury.

Traumatic Brain InjuryAnxiety

Shirley Ryan AbilityLab14 participantsStarted Dec 2020

Chicago, Illinois, United States

COMPLETEDPhase 12.2 miles

Avelumab in Metastatic or Locally Advanced Solid Tumors (JAVELIN Solid Tumor)

NCT01772004

This is a Phase 1, open-label, dose-escalation trial of avelumab \[antibody targeting programmed death ligand 1 (anti PD-L1)\] with consecutive parallel group expansion in participants with selected tumor indications. New recruitment is open for all active cohorts. Active cohorts: Escalation revised dosing regimen cohort. Closed cohorts: Non-small cell lung cancer (NSCLC, first line), NSCLC (post-platinum), metastatic breast cancer (MBC), colorectal cancer (CRC), urothelial carcinoma (secondary), mesothelioma, gastric/GEJ cancer (first line switch maintenance and second line), and ovarian cancer (secondary and platinum refractory + liposomal doxorubicin), renal cell carcinoma (second line) melanoma and head, neck squamous cell carcinoma (HNSCC), castrate-resistant prostate cancer (CRPC), adrenocortical carcinoma (ACC) urothelial carcinoma (efficacy), gastric/gastroesophageal junction (GEJ) cancer (third line), renal cell carcinoma (RCC, first line) and escalation phase .

Solid Tumors

EMD Serono Research & Development Institute, Inc.1,756 participantsStarted Jan 2013

Goodyear, Arizona, United States • Scottsdale, Arizona, United States • Scottsdale, Arizona, United States +71 more locations

Sleep Quality, Heart Rate Variability and Anxiety Following Brain Injury

Avelumab in Metastatic or Locally Advanced Solid Tumors (JAVELIN Solid Tumor)

Find Trials by Condition in Chicago

Study to Evaluate the Safety, Tolerability, and Efficacy of Armodafinil as Treatment for Patients With Excessive Sleepiness Associated With Mild or Moderate Closed Traumatic Brain Injury

Enhanced Recovery Pathway for Endoscopy

Phase 2 Efficacy, Safety, and Tolerability Study of Natalizumab in Focal Epilepsy

Intraoperative Methadone for Postoperative Pain Control After Thoracic Surgery

Restore EF Observational Study

Study of the Intradermal Injection of rHuPH20 or Placebo in Participants With Nickel Allergic Contact Dermatitis

T-Guard as Treatment for Steroid Refractory Acute GVHD (BMT CTN 1802)

Randomized Endo-Vein Graft Prospective

A Study of Gantenerumab in Participants With Prodromal Alzheimer's Disease

Evaluation of the Efficacy and Safety of BLU-5937 in Adults With Refractory Chronic Cough

Deep Phenotyping in Patients With ALS

A Study of Luspatercept (ACE-536) to Treat Anemia Due to Very Low, Low, or Intermediate Risk Myelodysplastic Syndromes

Study of BTK Inhibitor, Ibrutinib in Combination With Carfilzomib in Subjects With Relapsed and Refractory Multiple Myeloma

Clinical Trial to Evaluate the Efficacy of OC-02 Nasal Spray on Signs and Symptoms of Dry Eye Disease (The PEARL Study)

Study to Evaluate Safety and Preliminary Efficacy of Tafasitamab With Idelalisib or Venetoclax in R/R CLL/SLL Patients Pretreated With BTKi

Open-Label Extension Trial to Characterize the Long-term Safety and Tolerability of Elamipretide in Subjects With Genetically Confirmed Primary Mitochondrial Myopathy (PMM)

Participant Reported Outcomes With Use of Trifarotene 50 μg/g Cream in the Treatment of Moderate Facial and Truncal Acne Vulgaris

PREMOD2 With Near Infrared Spectroscopy Sub-study