Clinical Trials in Chicago

Showing 4421-4440 of 20,493 trials

Improving Scientific Rigor of Renal Clinical Endpoints for Sickle Cell Anemia

NCT04380610

The investigators will attempt to develop a more accurate equation to estimate eGFR in pediatric and adult sickle cell patients

Sickle Cell DiseaseRenal DiseaseGlomerular Disease

University of Alabama at Birmingham120 participantsStarted May 2021

Birmingham, Alabama, United States • Chicago, Illinois, United States • Memphis, Tennessee, United States +1 more locations

COMPLETEDPhase 2/32.2 miles

Study of Recombinant Protein Vaccines With Adjuvant as a Primary Series and as a Booster Dose Against COVID-19 in Adults 18 Years of Age and Older

NCT04762680

The primary objectives of the study are: To assess the safety profile of the study vaccines in each study intervention group. To assess the neutralizing antibody profile after primary series vaccination in SARS-CoV-2-naïve adults. To demonstrate that a booster dose of monovalent or bivalent SARS-CoV-2 vaccine given to adults previously vaccinated with an authorized/approved COVID-19 vaccine induces an immune response that is non-inferior to the response induced by a twodose priming series with the monovalent vaccine, and superior to that observed immediately before booster. The secondary objectives of the study are: To assess the neutralizing and binding antibody profiles after primary series vaccination at pre-defined time points during the study. To assess the neutralizing and binding antibody responses of booster vaccination. To describe the occurrences of laboratory-confirmed symptomatic COVID19 after primary series and booster vaccination. To describe the occurrences of serologically-confirmed SARS-CoV-2 infection after primary series vaccination.

COVID-19

Sanofi Pasteur, a Sanofi Company3,159 participantsStarted Feb 2021

Birmingham, Alabama, United States • Chandler, Arizona, United States • Glendale, Arizona, United States +63 more locations

Improving Scientific Rigor of Renal Clinical Endpoints for Sickle Cell Anemia

Study of Recombinant Protein Vaccines With Adjuvant as a Primary Series and as a Booster Dose Against COVID-19 in Adults 18 Years of Age and Older

Find Trials by Condition in Chicago

An Extension Study of Oral Ozanimod for Moderately to Severely Active Crohn's Disease

Study of LN-145, Autologous Tumor Infiltrating Lymphocytes in the Treatment of Patients With Cervical Carcinoma

Novartis - Closing the Gap in Cardiovascular Risk: Engage, Empower, Evaluate

Study of RiMO-301 and Radiotherapy With PD-1 Inhibitor for the Treatment of Head-Neck Cancer

Compare the Diuretic Effect With Furosemide vs Furosemide and Albumin Combined in Cirrhotic Patients

A Study of Danavorexton in People With Obstructive Sleep Apnea After General Anesthesia for Abdominal Surgery

Efficacy and Safety of Obefazimod in Subjects With Moderately to Severely Active Crohn's Disease

Omnipod 5 System Compared to Pump Therapy

The Use of Mentoring to Promote Well-being for Female SMART Members

Dexmedetomidine in the Treatment of Agitation Associated With Schizophrenia and Bipolar Disorder (SERENITY III)

Cobimetinib in Refractory Langerhans Cell Histiocytosis (LCH), and Other Histiocytic Disorders

BSB-1001 in Patients Undergoing HLA-Matched Allogenic Hematopoietic Stem Cell Transplant for AML, ALL or MDS

EASE: The Materna Prep Pivotal Study

Safety, Pharmacokinetics, and Preliminary Efficacy of Isatuximab in Patients Awaiting Kidney Transplantation

ACT-GLOBAL THROMBOLYSIS (ACT-WHEN-001) Domain Within the ACT-GLOBAL Adaptive Platform Trial-NCT06352632

Assessing the Time Demands of Cancer

Study of FIH of STX-241 in Locally Advanced or Metastatic NSCLC Resistant to EGFR TKIs

Dupilumab Skin Barrier Function Study in Atopic Dermatitis